PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp57577_TGAC_v2_mRNA38681
Organism
Trifolium pratense
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
Family ARF
Protein Properties Length: 849aa    MW: 94028.6 Da    PI: 6.2094
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp57577_TGAC_v2_mRNA38681genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B372.64.7e-23131232199
                                EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT CS
                         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkeg 77 
                                f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +g
  Tp57577_TGAC_v2_mRNA38681 131 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDVEWKFRHIFRGQPKRHLLTTGWSIFVSAKRLVAG 212
                                99*****************************8544444..48****************************************** PP

                                -EEEEEE-SSSEE..EEEEE-S CS
                         B3  78 DfvvFkldgrsefelvvkvfrk 99 
                                D+v+F   ++++ +l+++++r+
  Tp57577_TGAC_v2_mRNA38681 213 DSVLFI--WNEKNQLLLGIRRA 232
                                ******..8899999****997 PP
2Auxin_resp1187.8e-39257340183
                 Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                                aahaa+t+s F+v+YnPras+seFv++++k+ ka++ +++svGmRf+m fete+ss rr++Gt++g+sdld vrWpnS+Wrs+k
  Tp57577_TGAC_v2_mRNA38681 257 AAHAAATNSCFTVFYNPRASPSEFVIPLSKYIKAVYhTRISVGMRFRMLFETEESSVRRYMGTITGISDLDAVRWPNSHWRSVK 340
                                79*********************************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019363.14E-49115260IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.104.6E-41124246IPR015300DNA-binding pseudobarrel domain
CDDcd100172.12E-21130231No hitNo description
PfamPF023622.5E-21131232IPR003340B3 DNA binding domain
PROSITE profilePS5086312.308131233IPR003340B3 DNA binding domain
SMARTSM010196.4E-24131233IPR003340B3 DNA binding domain
PfamPF065072.2E-34257340IPR010525Auxin response factor
PfamPF023091.4E-8711806IPR033389AUX/IAA domain
SuperFamilySSF542776.47E-7720796No hitNo description
PROSITE profilePS5174524.655722806IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 849 aa     Download sequence    Send to blast
MKLSTSGLGQ QGQHEGGGGE KKCLNSELWH ACAGPLVSLP TAGTRVVYFP QGHSEQVSAT  60
TNREIDGHIP NYPSLPPQLV CQLHNVTMHA DVETDEVYAQ MTLQPLTPEE QKDTFLPMEL  120
GIPSKQPSNY FCKTLTASDT STHGGFSVPR RAAEKVFPPL DFSQQPPAQE LIARDLHDVE  180
WKFRHIFRGQ PKRHLLTTGW SIFVSAKRLV AGDSVLFIWN EKNQLLLGIR RANRPQTVMP  240
SSVLSSDSMH IGLLAAAAHA AATNSCFTVF YNPRASPSEF VIPLSKYIKA VYHTRISVGM  300
RFRMLFETEE SSVRRYMGTI TGISDLDAVR WPNSHWRSVK VGWDESTAGE RQPRVSLWEI  360
EPLTTFPMYP SLFPLRLKRP WHPGTSSLLD GRDEANGLMW MRGGPADQGL NSLNFQGASG  420
LLPWMQQRLD PTLLGSDQSQ QYQAMLAAGL QNMGSGGYLM RPQMMNFQQQ PINYLQSGNN  480
NSSLQLQQPQ IIQQTVNMMP QPQAQVLTEN LSQLLQKPNN NQEVQAQQQQ HSYQDTLLIQ  540
NDQLHQRQQS NLPSPSYSKP DFLESNIKFS ASVPSGQNML GSLCPEGTGN LLNLSTLSRS  600
GQSLMTEQLP QQSWTPKYGN MQVNVFGSSM SHAQYSGKES GMVSSHCDSD AQNHTLSGVN  660
IDSSGLLLPT TVPGYTTSSA DTSASTMQLG ESGFQGSLYA CIQDSSSFLQ NAEQNDPQNQ  720
NPTFVKVYKS GSVGRSLDIS RFNSYRELRE ELGQMFGIEG KLEDPLRSGW QLVFVDREND  780
VLLLGDDPWE SFVNNVWYIK ILSPEDIQKM GEQAVETLAL GSVQRLNGSG ESHHIVSGQP  840
PSIGSLEY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1601836145388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp57577_TGAC_v2_mRNA38681
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1515290.0AC151529.20 Medicago truncatula clone mth2-7n23, complete sequence.
GenBankCU4682440.0CU468244.3 M.truncatula DNA sequence from clone MTH2-16M9 on chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012571326.10.0auxin response factor 8
RefseqXP_012571327.10.0auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A1S3E6850.0A0A1S3E685_CICAR; Auxin response factor
STRINGXP_004500428.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]