PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp6g29080
Organism
Thellungiella parvula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassicaceae incertae sedis; Schrenkiella
Family E2F/DP
Protein Properties Length: 352aa    MW: 39947.5 Da    PI: 9.1112
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp6g29080genomethellungiellaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP71.59.3e-231176171
    E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
               rk+ksL++l ++flkl+++++ + + l+++a +L    v  +rRRiYD++N+Le+++l++++ kn+++wkg
  Tp6g29080 11 RKDKSLGVLVSNFLKLYNREDVDLIGLDDAAGKL---GV--ERRRIYDVVNILESIGLVARRGKNQYSWKG 76
               79*****************999************...**..****************************98 PP
2E2F_TDP76.92e-24136216171
    E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                +keksL++l+q+f+kl+ +s+++ +tl+ ++k+L++      ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  Tp6g29080 136 KKEKSLWVLAQNFVKLFLCSDDNLITLDGATKALLNVsqdpmNMRTKVRRLYDIANVFSSMNLIEKtnipeTRKPAYRWLG 216
                69********************************887999***************************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.3E-24777IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467857.76E-161074IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.6E-261176IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.0E-191276IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.0E-21134218IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.7E-28136216IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.5E-19137216IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-11138217IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
MEPLGRQSYS RKDKSLGVLV SNFLKLYNRE DVDLIGLDDA AGKLGVERRR IYDVVNILES  60
IGLVARRGKN QYSWKGFGEV PRVLSELKEE GMREKFGIIP CVTNSEMVLY DEVREEPLKL  120
SPDDQENTTS PKLDSKKEKS LWVLAQNFVK LFLCSDDNLI TLDGATKALL NVSQDPMNMR  180
TKVRRLYDIA NVFSSMNLIE KTNIPETRKP AYRWLGAKAI SEDRFLAGPA SRCDRNEPKK  240
RVFGTEITNF NTKRAKTDCS KDLKHYGNQN TCSVIKQEQC DSKPDVKSFV GPLSPADTSK  300
KTNVGKNNNQ SIEVLETLAS THKLQYCNPE LIGLLGHYSE TWKSWHAEFG RK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-32102083228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00511DAPTransfer from AT5G14960Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp6g29080
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006400017.10.0E2F transcription factor-like E2FD
RefseqXP_009126020.10.0PREDICTED: E2F transcription factor-like E2FD
SwissprotQ9LFQ91e-173E2FD_ARATH; E2F transcription factor-like E2FD
TrEMBLA0A398A7J60.0A0A398A7J6_BRACM; Uncharacterized protein
STRINGXP_006400017.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G14960.11e-175DP-E2F-like 2