PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Traes_2DL_362A1F535.1

Organism

Triticum aestivum

Taxonomic ID

4565

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum

Family

WRKY

Protein Properties

Length: 70aa MW: 8363.38 Da PI: 9.6785

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Traes_2DL_362A1F535.1	genome	IWGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	57.1	3.6e-18	24	70	2	45
--SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSST CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedp 45 +Dg +WrKYGqKe+++s+++++Y+rCt++ +C+++++ +r+++dp Traes_2DL_362A1F535.1 24 EDGQTWRKYGQKEIQNSKHSKAYFRCTHKydqQCMARRQAQRCDDDP 70 8*************************99999*********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.3E-17	14	70	IPR003657	WRKY domain
SuperFamily	SSF118290	4.84E-18	17	70	IPR003657	WRKY domain
PROSITE profile	PS50811	15.916	18	70	IPR003657	WRKY domain
SMART	SM00774	8.7E-16	23	70	IPR003657	WRKY domain
Pfam	PF03106	5.1E-15	24	69	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 70 aa Download sequence Send to blast
NIFFLGRCRT QDSSVVTKNM KSLEDGQTWR KYGQKEIQNS KHSKAYFRCT HKYDQQCMAR 60 RQAQRCDDDP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6ir8_A	2e-27	13	70	1	55	OsWRKY45
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the regulation of osmotic stress responses and stomatal movement (PubMed:24773321). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). {ECO:0000250, ECO:0000269\|PubMed:22316300, ECO:0000269\|PubMed:22325892, ECO:0000269\|PubMed:24773321, ECO:0000269\|PubMed:28576847}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by drought, salt and hydrogen peroxide treatments (PubMed:24773321). Induced by salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Up-regulated by E.amylovora (PubMed:22316300). Triggered by P.syringae (PubMed:22325892). {ECO:0000269\|PubMed:22268143, ECO:0000269\|PubMed:22316300, ECO:0000269\|PubMed:22325892, ECO:0000269\|PubMed:24773321}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EF397613	3e-92	EF397613.1 Triticum aestivum cultivar Nongda 3338 WRKY45 transcription factor (WRKY45) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020165252.1	1e-39	probable WRKY transcription factor 70
Swissprot	Q9SKD9	2e-15	WRK46_ARATH; Probable WRKY transcription factor 46
TrEMBL	A0A191XX45	6e-39	A0A191XX45_WHEAT; WRKY transcription factor (Fragment)
TrEMBL	F8WPI9	8e-39	F8WPI9_WHEAT; WRKY45-like transcription factor
STRING	Traes_2DL_362A1F535.1	2e-46	(Triticum aestivum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP7656	35	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G46400.1	7e-12	WRKY DNA-binding protein 46

Publications ? help Back to Top
Brenchley R, et al. Analysis of the bread wheat genome using whole-genome shotgun sequencing. Nature, 2012. 491(7426): p. 705-10 [PMID:23192148] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sheikh AH, et al. Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana. Front Plant Sci, 2016. 7: p. 61 [PMID:26870073] Yan JY, et al. A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency. Plant Physiol., 2016. 171(3): p. 2017-27 [PMID:27208259] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. Plant Cell, 2017. 29(6): p. 1425-1439 [PMID:28576847] Ma J, et al. Overexpression of TaWRKY146 Increases Drought Tolerance through Inducing Stomatal Closure in Arabidopsis thaliana. Front Plant Sci, 2017. 8: p. 2036 [PMID:29225611]