PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Traes_5AL_7FFD17EDE.2
Organism
Triticum aestivum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
Family E2F/DP
Protein Properties Length: 372aa    MW: 40967.2 Da    PI: 4.3011
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Traes_5AL_7FFD17EDE.2genomeIWGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.41.8e-2659124171
                E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                            r+++sL+llt+kfl+ll+ ++ g+v+ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  Traes_5AL_7FFD17EDE.2  59 RYDSSLGLLTKKFLNLLKGAPGGMVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 124
                            6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.9E-2857125IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-3459124IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.35E-1659122IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.5E-2361124IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.00E-49135241No hitNo description
SuperFamilySSF1440743.14E-33136241No hitNo description
PfamPF164211.5E-33140239IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 372 aa     Download sequence    Send to blast
MMSPGYANAA NSPIPTLPSG KGSKMSAKPK AAKGQKSCPQ TPLFSGSPGN PATPVGGCRY  60
DSSLGLLTKK FLNLLKGAPG GMVDLNNAAE TLEVQKRRIY DITNVLEGIG LIEKKLKNNI  120
RWKGIDDSRP GEVSDDMSIL QGDIEALTLQ EHSLDGQISE MRDKLRELTE DENNQKWLYV  180
TEDDIKSLPC FQNQTLIAIK APHGTTLEVP DPDEVNDYPQ RRYRIVLRST MGPIDVYLVS  240
QFEEMSGMET PPRPAQTISM DYLENPRTPL ATGSNKDVEM ENVQQGLIMP PDAPTTQDIG  300
GMMKIVPSEL DTDADYWLLS DTGVSITDMW KTAPDVEWEG IDINAEDFLE VGTPRQQDQP  360
PSEMVDHPSC IS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-2351125274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020177970.10.0transcription factor E2FA-like
SwissprotQ9FNY01e-114E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A3B6KDY00.0A0A3B6KDY0_WHEAT; Uncharacterized protein
TrEMBLA0A3B6KFF50.0A0A3B6KFF5_WHEAT; Uncharacterized protein
STRINGTraes_5AL_7FFD17EDE.20.0(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-107E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]
  2. Brenchley R, et al.
    Analysis of the bread wheat genome using whole-genome shotgun sequencing.
    Nature, 2012. 491(7426): p. 705-10
    [PMID:23192148]