PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Traes_6BL_01A973403.1
Organism
Triticum aestivum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
Family E2F/DP
Protein Properties Length: 72aa    MW: 8017.44 Da    PI: 11.4542
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Traes_6BL_01A973403.1genomeIWGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP42.98.2e-141373971
                E2F_TDP 39 vknkrRRiYDilNVLealnliek....kekneirwkg 71
                           +++k+RR+YDi+NVL++l+liek    ++k+++rw g
  Traes_6BL_01A973403.1  1 MRTKVRRLYDIANVLSSLKLIEKtqvdTRKPAFRWLG 37
                           689**********************999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF023191.8E-11137IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.58E-8238IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.108.9E-13338IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 72 aa     Download sequence    Send to blast
MRTKVRRLYD IANVLSSLKL IEKTQVDTRK PAFRWLGMAG KPKAENGVTI VASPASKTLS  60
NKRVFGTELT NI
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020187635.12e-41E2F transcription factor-like E2FE isoform X1
RefseqXP_020187636.12e-41E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ43e-19E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A453PLA89e-43A0A453PLA8_AEGTS; Uncharacterized protein
TrEMBLA0A453PLF71e-41A0A453PLF7_AEGTS; Uncharacterized protein
TrEMBLA0A453PLG21e-41A0A453PLG2_AEGTS; Uncharacterized protein
STRINGTraes_6BL_01A973403.11e-45(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.11e-21DP-E2F-like 1
Publications ? help Back to Top
  1. Brenchley R, et al.
    Analysis of the bread wheat genome using whole-genome shotgun sequencing.
    Nature, 2012. 491(7426): p. 705-10
    [PMID:23192148]
  2. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  3. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  4. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]