PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Vang05g02900.1
Organism
Vigna angularis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna
Family E2F/DP
Protein Properties Length: 388aa    MW: 44393.7 Da    PI: 5.3314
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Vang05g02900.1genomeSNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.11.1e-26106171171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++ +++g+++ln+ a+ L   +v  ++RRiYDi+NVLe+++liek++kn+i+wkg
  Vang05g02900.1 106 RYDSSLGLLTKKFVSLIQDARDGTLDLNKTAEIL---EV--QKRRIYDITNVLEGVGLIEKTSKNHIQWKG 171
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.5E-29103172IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-34106171IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.72E-17106169IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.8E-25108171IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146604.11E-34182290No hitNo description
SuperFamilySSF1440741.36E-25183290No hitNo description
PfamPF164213.7E-24187287IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 388 aa     Download sequence    Send to blast
LLMSTSGQDH HQSHDPSHPS QFKFHLLHSP SHISPLPHYL FPNFFPSQRY ENSHRSNLEV  60
VPPPVQTQST ERGKQNGKSK LSRNTKSGTH RPSADSPNLT AVNNCRYDSS LGLLTKKFVS  120
LIQDARDGTL DLNKTAEILE VQKRRIYDIT NVLEGVGLIE KTSKNHIQWK GCDGLGPREL  180
ENQINGLKAE VESLYARECE LDDCIRKKQE LLRNLEESES SQKYLFLTKE EILSLPCFQN  240
QEIIAIKAPK ASFIEVPDPD EVESVFRQRQ YKMIVRSATG PIYLYLLSKD DCKYEDDSVK  300
RVKLMDPSWN SEQCIKRGVG LLESHDDKQN TSESFNFHES QASGIQEITP TDFEMEDDYW  360
FQSDPGVRLT QLWENEPILP IDELPDY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A7e-25105172674PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapVang05g02900.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017435127.10.0PREDICTED: transcription factor E2FC-like isoform X1
SwissprotQ9FV702e-87E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A0S3RB490.0A0A0S3RB49_PHAAN; Uncharacterized protein
STRINGXP_007136084.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF118852529
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.23e-87E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]