PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Vang06g25180.1
Organism
Vigna angularis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna
Family E2F/DP
Protein Properties Length: 492aa    MW: 54398.1 Da    PI: 5.291
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Vang06g25180.1genomeSNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.77e-27182247171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Vang06g25180.1 182 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 247
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.2E-29179249IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-34182247IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.21E-17182245IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.9E-24184247IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440743.92E-27260377No hitNo description
CDDcd146601.11E-44260377No hitNo description
PfamPF164213.4E-29263375IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 492 aa     Download sequence    Send to blast
MSTAAGPPDR RASPPRGTAG TTIRPALKRH LAFVTKPPFA PPDDYHSFSS IDSRRLADEA  60
VVVRSPVSTS VSSARSQIHL RGSRIWNVLF CVECDYMKRK GGMNDSEGES HTQKWSNSPG  120
YTNVSNITNS PFKTPVSAKG GRTQKAKASK EGRSCPPTPI SNADSFSDSG SPSPLTPASS  180
CRYDSSLGLL TKKFINLVKH AEDGILDLNK AAETLEVQKR RIYDITNVLE GIGLIEKKLK  240
NRIHWKGIES STSGEVDGDI SVLKEEVEKL SLEEQGLDDQ IREMQERLRK LSENENNRKC  300
LFVTEDDIKS LPCFQVFLLL ILAYSCKQNE TLIAIKAPHG TTLEVPDPEE AVDYPQRRYR  360
IILRSTMGPI DVYLISQFEE KFEEINGAEL PMIPLASSSE SNEQVMTEMV PAECSGKEFE  420
PQTQLSSHND ADYWLLSDAD VSITDMWRTD STVDWNGVDM LNPDFGIISR PQTPSSGFVE  480
VPTPGANSNH K*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-25177248274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapVang06g25180.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0150411e-157AP015041.1 Vigna angularis var. angularis DNA, chromosome 8, almost complete sequence, cultivar: Shumari.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017407031.10.0PREDICTED: transcription factor E2FA
SwissprotQ9FNY01e-132E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0L9T8L30.0A0A0L9T8L3_PHAAN; Uncharacterized protein
STRINGXP_007145806.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-123E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]