PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Vun001309
Organism
Vigna unguiculata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna
Family E2F/DP
Protein Properties Length: 380aa    MW: 42882.8 Da    PI: 9.4846
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Vun#S45958818PU_unrefUnigeneView CDS
PUT-167a-Vigna_unguiculata-13321PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP75.84.2e-241580171
    E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
               rk+ksL+ll+++fl+l+++ +   + l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Vun001309 15 RKQKSLGLLCTNFLSLYNRDTVHLIGLDDAATRL---GV--ERRRIYDIVNVLESIGVLSRKAKNQYTWKG 80
               79*****************999************...**..****************************98 PP
2E2F_TDP75.26.6e-24151231171
    E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                r+eksL lltq+f+kl+ +s+ + ++l+e+ak L+ +      +++k+RR+YDi+NVL+++ liek     ++k+++rw g
  Vun001309 151 RREKSLALLTQNFVKLFVCSNVELISLDEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMSLIEKthtsdTRKPAFRWLG 231
                689**************************************999**************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.9E-261181IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.04E-161478IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-281580IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.0E-201680IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.9E-23148233IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.4E-31151231IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.4E-19153231IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.21E-13153232IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 380 aa     Download sequence    Send to blast
XSSDPISSKH YTYNRKQKSL GLLCTNFLSL YNRDTVHLIG LDDAATRLGV ERRRIYDIVN  60
VLESIGVLSR KAKNQYTWKG FAAIPLTLRE LKEDGLRENS SSLRGSTNDD MDKVSDDEDD  120
EETQSNAATG SQNDKLNPKS TQPRSLKNEN RREKSLALLT QNFVKLFVCS NVELISLDEA  180
AKLLLGDAHN TSIMRTKVRR LYDIANVLSS MSLIEKTHTS DTRKPAFRWL GPEGKTWNES  240
LHKSNQNESR KRAFGSDITN ISFERNKVEL FTNGDLNSNP KKLKVENDRG PGQADENDLK  300
QGNKQTPKSY QFGPFAPACV PGVGASGNNN VKQVHDWNGL VTAHSPQYQN EALRDLFSHY  360
MEAWKSWYSE IAAKRPLKIL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A7e-40142233228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027917841.10.0E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-126E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A4D6KXP20.0A0A4D6KXP2_VIGUN; E2F transcription factor 7/8
STRINGXP_007155383.10.0(Phaseolus vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-128DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]