PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

WALNUT_00005611-RA

Organism

Juglans regia

Taxonomic ID

51240

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans

Family

GRAS

Protein Properties

Length: 513aa MW: 57978.1 Da PI: 6.8203

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
WALNUT_00005611-RA	genome	JHU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	351.3	1.6e-107	152	507	1	374
GRAS 1 lvelLlecAeavssgdlelaqalLarlselaspdg.dpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPi 90 l+++LlecA a+s ++l +a+++L +l ++ sp+g + +R++ayf+ A+++r+ +s+ ++++ l ++ a+++f++vsP+ WALNUT_00005611-RA 152 LITQLLECAVAISVDNLGEAHRMLLELTQTGSPYGiSCAERVVAYFAMAMSSRVINSWLGTCSPLVNYKS-------IHGAFQVFNNVSPF 235 5789*****************************999**************99999977655444.......46799***** PP GRAS 91 lkfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvl 181 +kf+h+t NqaIlea+++ +rvHi+D+di+qGlQWpaL++ La+R egpp++R+Tg+g+ s e+l etg++La+fA++lg++fef++ WALNUT_00005611-RA 236 IKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPHVRMTGMGK----SMEMLLETGKQLANFAKRLGMSFEFHP- 321 *******************************************************....***********************. PP GRAS 182 vakrledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsle 272 +a+++ +++ ++ +v++gE+laV++ h+l+d +++ + +++l+k+lsP + ++veq+++h ++sFl+rf+ +l+yys+lfdsl WALNUT_00005611-RA 322 IARKFGEIDASMVQVRRGETLAVHWLQ--HSLYDATGPDWK----TMRLLKELSPSITTLVEQDISH-GGSFLDRFVGSLHYYSTLFDSLG 405 7*********************9..999999999888....******************.789**************** PP GRAS 273 aklpreseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvk.sdgyrveeesgslvlgW 362 a+lp ++ +r+ vE+ ll+rei n+ a g +r + ++++W++ l + F ++p+s + ++qa+l+l++++ +gy++ e +g+l lgW WALNUT_00005611-RA 406 ANLPIDDPNRHRVEHCLLHREINNIMAIGGPARSGED-KFRHWKMELARNCFVQMPMSGNSMAQAQLILNMFPpAHGYSLVEGDGTLRLGW 495 ****************************77665.5************************************************ PP GRAS 363 kdrpLvsvSaWr 374 kd +L+++SaW+ WALNUT_00005611-RA 496 KDTSLYTASAWT 507 *********6 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50985	51.398	126	486	IPR005202	Transcription factor GRAS
Pfam	PF03514	5.4E-105	152	507	IPR005202	Transcription factor GRAS

Sequence ? help Back to Top
Protein Sequence Length: 513 aa Download sequence Send to blast
MKAGFEVVQG ALDMIQPHEP WDIYQPAAVG FPTPTSFNPF LVKPIIENRC LNMERNELSD 60 WVEQITRQLI EDLPEATGSD HHHHVLHSET KSQDNNIVAS FSGEFRPRKA PKRSHFDTIG 120 NELQWSNVEP HHVYDHGMNK GLNRVDEHGL TLITQLLECA VAISVDNLGE AHRMLLELTQ 180 TGSPYGISCA ERVVAYFAMA MSSRVINSWL GTCSPLVNYK SIHGAFQVFN NVSPFIKFAH 240 FTSNQAILEA FHRRDRVHIL DLDIMQGLQW PALFHILATR MEGPPHVRMT GMGKSMEMLL 300 ETGKQLANFA KRLGMSFEFH PIARKFGEID ASMVQVRRGE TLAVHWLQHS LYDATGPDWK 360 TMRLLKELSP SITTLVEQDI SHGGSFLDRF VGSLHYYSTL FDSLGANLPI DDPNRHRVEH 420 CLLHREINNI MAIGGPARSG EDKFRHWKME LARNCFVQMP MSGNSMAQAQ LILNMFPPAH 480 GYSLVEGDGT LRLGWKDTSL YTASAWTFNA SSR

Sequence ? help Back to Top

Protein Sequence Length: 513 aa Download sequence Send to blast

MKAGFEVVQG ALDMIQPHEP WDIYQPAAVG FPTPTSFNPF LVKPIIENRC LNMERNELSD  60
WVEQITRQLI EDLPEATGSD HHHHVLHSET KSQDNNIVAS FSGEFRPRKA PKRSHFDTIG  120
NELQWSNVEP HHVYDHGMNK GLNRVDEHGL TLITQLLECA VAISVDNLGE AHRMLLELTQ  180
TGSPYGISCA ERVVAYFAMA MSSRVINSWL GTCSPLVNYK SIHGAFQVFN NVSPFIKFAH  240
FTSNQAILEA FHRRDRVHIL DLDIMQGLQW PALFHILATR MEGPPHVRMT GMGKSMEMLL  300
ETGKQLANFA KRLGMSFEFH PIARKFGEID ASMVQVRRGE TLAVHWLQHS LYDATGPDWK  360
TMRLLKELSP SITTLVEQDI SHGGSFLDRF VGSLHYYSTL FDSLGANLPI DDPNRHRVEH  420
CLLHREINNI MAIGGPARSG EDKFRHWKME LARNCFVQMP MSGNSMAQAQ LILNMFPPAH  480
GYSLVEGDGT LRLGWKDTSL YTASAWTFNA SSR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_A	1e-144	143	507	9	378	Protein SCARECROW
5b3h_D	1e-144	143	507	9	378	Protein SCARECROW
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for cell division but not differentiation of the ground tissue. Also required for normal shoot gravitropism. Regulates the radial organization of the shoot axial organs. Binds to the promoter of MGP, NUC, RLK and SCL3. Restricts SHR movment and sequesters it into the nucleus of the endodermis. {ECO:0000269\|PubMed:10631180, ECO:0000269\|PubMed:12569126, ECO:0000269\|PubMed:15142972, ECO:0000269\|PubMed:15314023, ECO:0000269\|PubMed:16640459, ECO:0000269\|PubMed:17446396, ECO:0000269\|PubMed:22921914, ECO:0000269\|PubMed:24302889, ECO:0000269\|PubMed:8819871, ECO:0000269\|PubMed:9375406, ECO:0000269\|PubMed:9670559}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by SHR and by itself. {ECO:0000269\|PubMed:10850497, ECO:0000269\|PubMed:11565032, ECO:0000269\|PubMed:15314023}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018827159.1	0.0	PREDICTED: protein SCARECROW-like
Swissprot	Q9M384	1e-140	SCR_ARATH; Protein SCARECROW
TrEMBL	A0A2I4F682	0.0	A0A2I4F682_JUGRE; protein SCARECROW-like
STRING	POPTR_0005s24850.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF11787	31	38

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G54220.1	1e-143	GRAS family protein

Publications ? help Back to Top
Liu YG, et al. Complementation of plant mutants with large genomic DNA fragments by a transformation-competent artificial chromosome vector accelerates positional cloning. Proc. Natl. Acad. Sci. U.S.A., 1999. 96(11): p. 6535-40 [PMID:10339623] Ticconi CA, et al. ER-resident proteins PDR2 and LPR1 mediate the developmental response of root meristems to phosphate availability. Proc. Natl. Acad. Sci. U.S.A., 2009. 106(33): p. 14174-9 [PMID:19666499] Moubayidin L, et al. Spatial coordination between stem cell activity and cell differentiation in the root meristem. Dev. Cell, 2013. 26(4): p. 405-15 [PMID:23987513] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Reyes-Hernández BJ, et al. The root indeterminacy-to-determinacy developmental switch is operated through a folate-dependent pathway in Arabidopsis thaliana. New Phytol., 2014. 202(4): p. 1223-36 [PMID:24635769] Gao X,Wang C,Cui H Identification of bundle sheath cell fate factors provides new tools for C3-to-C4 engineering. Plant Signal Behav, 2018. [PMID:24819776] Ron M, et al. Hairy root transformation using Agrobacterium rhizogenes as a tool for exploring cell type-specific gene expression and function using tomato as a model. Plant Physiol., 2014. 166(2): p. 455-69 [PMID:24868032] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Gong X, et al. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol., 2016. 170(3): p. 1675-83 [PMID:26818732] Moubayidin L, et al. A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis. Planta, 2016. 243(5): p. 1159-68 [PMID:26848984] Madmon O, et al. Expression of MAX2 under SCARECROW promoter enhances the strigolactone/MAX2 dependent response of Arabidopsis roots to low-phosphate conditions. Planta, 2016. 243(6): p. 1419-27 [PMID:26919985] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Benfey PN Defining the Path from Stem Cells to Differentiated Tissue. Curr. Top. Dev. Biol., 2016. 116: p. 35-43 [PMID:26970612] Li Q,Zhao Y,Yue M,Xue Y,Bao S The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage. J Genet Genomics, 2016. 43(4): p. 187-97 [PMID:27090604] Clark NM, et al. Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. Elife, 2017. [PMID:27288545] Choi JW,Lim J Control of Asymmetric Cell Divisions during Root Ground Tissue Maturation. Mol. Cells, 2016. 39(7): p. 524-9 [PMID:27306644] Yoon EK, et al. Conservation and Diversification of the SHR-SCR-SCL23 Regulatory Network in the Development of the Functional Endodermis in Arabidopsis Shoots. Mol Plant, 2016. 9(8): p. 1197-1209 [PMID:27353361] Waszczak C, et al. SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions. Plant Cell, 2016. 28(8): p. 1844-59 [PMID:27432873] Goh T, et al. Quiescent center initiation in the Arabidopsis lateral root primordia is dependent on the SCARECROW transcription factor. Development, 2016. 143(18): p. 3363-71 [PMID:27510971] Yu Q, et al. A P-Loop NTPase Regulates Quiescent Center Cell Division and Distal Stem Cell Identity through the Regulation of ROS Homeostasis in Arabidopsis Root. PLoS Genet., 2016. 12(9): p. e1006175 [PMID:27583367] Sparks EE, et al. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Dev. Cell, 2016. 39(5): p. 585-596 [PMID:27923776] Hirano Y, et al. Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD. Nat Plants, 2017. 3: p. 17010 [PMID:28211915] Kobayashi A,Miura S,Kozaki A INDETERMINATE DOMAIN PROTEIN binding sequences in the 5'-untranslated region and promoter of the SCARECROW gene play crucial and distinct roles in regulating SCARECROW expression in roots and leaves. Plant Mol. Biol., 2017. 94(1-2): p. 1-13 [PMID:28324206] Díaz-Triviño S,Long Y,Scheres B,Blilou I Analysis of a Plant Transcriptional Regulatory Network Using Transient Expression Systems. Methods Mol. Biol., 2017. 1629: p. 83-103 [PMID:28623581] Long Y, et al. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 2017. 548(7665): p. 97-102 [PMID:28746306] Bruno L, et al. In Arabidopsis thaliana Cadmium Impact on the Growth of Primary Root by Altering SCR Expression and Auxin-Cytokinin Cross-Talk. Front Plant Sci, 2017. 8: p. 1323 [PMID:28798767] Mira MM, et al. Expression of Arabidopsis class 1 phytoglobin (AtPgb1) delays death and degradation of the root apical meristem during severe PEG-induced water deficit. J. Exp. Bot., 2017. 68(20): p. 5653-5668 [PMID:29059380] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938] Ercoli MF, et al. GIF Transcriptional Coregulators Control Root Meristem Homeostasis. Plant Cell, 2018. 30(2): p. 347-359 [PMID:29352064] Shimotohno A,Heidstra R,Blilou I,Scheres B Root stem cell niche organizer specification by molecular convergence of PLETHORA and SCARECROW transcription factor modules. Genes Dev., 2018. 32(15-16): p. 1085-1100 [PMID:30018102]