PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID WALNUT_00008048-RA
Organism
Juglans regia
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans
Family ARF
Protein Properties Length: 849aa    MW: 95196.9 Da    PI: 6.3679
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
WALNUT_00008048-RAgenomeJHUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.62.3e-23140241199
                         EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
                  B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                         f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F  
  WALNUT_00008048-RA 140 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDVEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFI- 227
                         99*****************************8544444..48************************************************. PP

                         -SSSEE..EEEEE-S CS
                  B3  85 dgrsefelvvkvfrk 99 
                          ++++ +l+++++r+
  WALNUT_00008048-RA 228 -WNEKNQLLLGIRRA 241
                         .8899999****997 PP
2Auxin_resp1171.6e-38266349183
          Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                         aahaa+t+s F+++YnPras+seFvv+++k++k++  ++vsvGmRf+m fete+ss rr++Gt++g+sdld+vrWpnS+Wrs+k
  WALNUT_00008048-RA 266 AAHAAATHSCFTIFYNPRASPSEFVVPLSKYVKTVFhTRVSVGMRFRMLFETEESSVRRYMGTITGISDLDSVRWPNSHWRSVK 349
                         79******************************9986599******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.62E-49124269IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.1E-41133255IPR015300DNA-binding pseudobarrel domain
CDDcd100172.62E-21139240No hitNo description
PfamPF023621.4E-21140241IPR003340B3 DNA binding domain
SMARTSM010191.1E-23140242IPR003340B3 DNA binding domain
PROSITE profilePS5086312.337140242IPR003340B3 DNA binding domain
PfamPF065071.5E-33266349IPR010525Auxin response factor
SuperFamilySSF542773.73E-6730804No hitNo description
PROSITE profilePS5174519.817734814IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009908Biological Processflower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 849 aa     Download sequence    Send to blast
MKLSTSGLSQ LDHEGGTGEK KCLNSELWHA CAGPLVSLPT PGTRVVYFPQ GHSEQVASLF  60
YSLPLVAATT NKEVDGHIPN YPSLSPQLIC QLHNVTMHAD VETDEVYAQM TLQPLTLEEQ  120
KDTFLPMELG IPSKQPANYF CKTLTASDTS THGGFSVPRR AAEKVFPPLD FSQQPPAQEL  180
IARDLHDVEW KFRHIFRGQP KRHLLTTGWS VFVSAKRLVA GDSVLFIWNE KNQLLLGIRR  240
ATRPQTVMPS SVLSSDSMHI GLLAAAAHAA ATHSCFTIFY NPRASPSEFV VPLSKYVKTV  300
FHTRVSVGMR FRMLFETEES SVRRYMGTIT GISDLDSVRW PNSHWRSVKV GWDESTAGER  360
QPRVSLWEIE PLTTFPMYPS LFPLRLKRPW HPGVSSLHDS RDEGTNNGLM WLRGGTGEHG  420
VNSLNFQGVG LFPWMQQRLD PTLFGNDHNQ QYQAMLAAGM QNLGSGDLLR QQIMQFQQPF  480
QYFQQRESHT SLLQQQQQQQ QQEAFTQTLP RNILQAQTQV LTENIPQHLI QQPLNNQQEE  540
QARQQQHTFQ NMVHIRSDQL HQRLQSNVPS SSFAKADFMD PGTKFSPSIT PRQNMVSSFC  600
PEGSSNFLNF SRVGQSMLAE QLPQQSWVSK YTHSQANTYA NSMSHTPYPG KDANEEPENC  660
NSDSQNPTLF GVNIDSSGLL LPTTLPTFAT SVDADVTSMP LGDSGFQSSL YGSVQDSSEL  720
LRSAGQVDPP TPSRTFVKVY KSGSVGRSLD ISRFSSYNEL REELAQMFGI EGMLEDPLRS  780
GWQLVFVDRE NDALLLGDDP WEYFHLRNVH KMGEQAVESF SPHVAQRLNN GGEVQDLVPG  840
LPSPGMLEY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1521137040388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00033PBMTransfer from AT5G37020Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018834144.10.0PREDICTED: LOW QUALITY PROTEIN: auxin response factor 8-like
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A2I4FR660.0A0A2I4FR66_JUGRE; Auxin response factor
STRINGXP_008343153.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]