PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_004497179.1
Organism
Cicer arietinum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer
Family bHLH
Protein Properties Length: 539aa    MW: 61562 Da    PI: 4.8129
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_004497179.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.16.6e-13345388755
                     HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                      +Er+RR+++N+++ +Lr+l+P  +      Kl+ a+iL  A+eY+k+Lq
  XP_004497179.1 345 VAERKRRKKLNDRLYNLRSLVPRiS------KLDRASILGDAIEYVKDLQ 388
                     68*********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.1E-1913161IPR025610Transcription factor MYC/MYB N-terminal
CDDcd000833.95E-13337392No hitNo description
PROSITE profilePS5088815.866338387IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.75E-17341402IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.2E-17344401IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.8E-16344393IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.0E-10345388IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516718.65449520IPR002912ACT domain
CDDcd048731.12E-4450514No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0009555Biological Processpollen development
GO:0048658Biological Processanther wall tapetum development
GO:0005634Cellular Componentnucleus
GO:0000978Molecular FunctionRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 539 aa     Download sequence    Send to blast
MNNNNFMMQN ITERLRPLVG LNGWDYCVSW KLSEDQRYLE WLGCCCGGSE SNQNGGEQHI  60
FLVSSSSSSS CRDTMFSHSR TKACDLLSQL NTSISTDSGI HAQTLLANQP NWLNYPNTLD  120
PNTLQETING THVLIPVPGG LVELFVTKQV GEDQQVLDFI TSQCIVLVDQ EGMNNSIGFN  180
SMSNMQSNQV VCDENDGNNK TNNHFHPSDS LSLPPHDHIS VMNFMQQFNY NYNYNQQNNR  240
MRNDETFSEE YQGSFFHDHE NSNNNLVKPN TEEEHEHKSL MTEEQYVFVN PLDSKKNQEE  300
EEKDLMKHVV GRSDSMSDCS DQNEEEEDGK YRRRNGKGNQ SKNLVAERKR RKKLNDRLYN  360
LRSLVPRISK LDRASILGDA IEYVKDLQKQ VKELQDDLDE NSDTATESNC VINNQYVNGY  420
HVVGNGNEKQ TQQMEAQVEV AQIDGNEYFV KVFCEHRAGG FVKLMEALNS LGMDVLHATV  480
TSHKGLVSNV FKVEKKESEI VEAEDVRESL IELLTRNRWN SDEKKMAHND QLLHIAASY
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1331352RRRNGKGNQSKNLVAERKRRKK
2346353ERKRRKKL
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269|PubMed:12535353, ECO:0000269|PubMed:24804694}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_004497179.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004497179.10.0transcription factor ABORTED MICROSPORES
RefseqXP_027189254.10.0transcription factor ABORTED MICROSPORES
SwissprotQ9ZVX21e-135AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBLA0A1S2XZY90.0A0A1S2XZY9_CICAR; transcription factor ABORTED MICROSPORES
STRINGXP_004497179.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF42253247
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16910.11e-132bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Jiang J,Zhang Z,Cao J
    Pollen wall development: the associated enzymes and metabolic pathways.
    Plant Biol (Stuttg), 2013. 15(2): p. 249-63
    [PMID:23252839]
  3. Xu J, et al.
    ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis.
    Plant Cell, 2014. 26(4): p. 1544-1556
    [PMID:24781116]
  4. Qian H, et al.
    Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis.
    Ecotoxicology, 2015. 24(1): p. 163-71
    [PMID:25348600]
  5. Xiong SX, et al.
    The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana.
    Plant J., 2016. 88(6): p. 936-946
    [PMID:27460657]
  6. Ferguson AC, et al.
    Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis.
    New Phytol., 2017. 213(2): p. 778-790
    [PMID:27787905]
  7. Lou Y, et al.
    Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana.
    New Phytol., 2018. 217(1): p. 378-391
    [PMID:28940573]
  8. Bi H,Fan W,Zhang P
    C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1689
    [PMID:29021807]