PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_004507106.1

Organism

Cicer arietinum

Taxonomic ID

3827

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer

Family

AP2

Protein Properties

Length: 567aa MW: 63345.1 Da PI: 6.3297

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_004507106.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	42.7	1.4e-13	167	226	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV+ ++++gr++A+++d + g ++ ++++lg ++ +e+Aa+ ++ a++k++g XP_004507106.1 167 SIYRGVTKHRWTGRYEAHLWDnSCRrEGqsRKgRQVYLGGYDKEEKAARSYDLAALKYWG 226 57*****************666664477446***********************98 PP
2	AP2	47	6.2e-15	271	320	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GV+++++ grW A+I + +k +lg+f t+eeAa+a++ a+ k++g XP_004507106.1 271 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTEEEAAEAYDIAAIKFRG 320 9*************988532...5**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	4.85E-22	167	236	No hit	No description
SuperFamily	SSF54171	4.77E-16	167	236	IPR016177	DNA-binding domain
Pfam	PF00847	1.6E-10	167	226	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	18.755	168	234	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.1E-14	168	235	IPR001471	AP2/ERF domain
SMART	SM00380	1.7E-29	168	240	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-6	169	180	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	5.62E-18	269	330	IPR016177	DNA-binding domain
CDD	cd00018	1.36E-24	269	330	No hit	No description
Gene3D	G3DSA:3.30.730.10	3.2E-18	270	329	IPR001471	AP2/ERF domain
SMART	SM00380	8.6E-33	270	334	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.375	270	328	IPR001471	AP2/ERF domain
Pfam	PF00847	1.5E-9	271	320	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-6	310	330	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000723	Biological Process	telomere maintenance
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0007389	Biological Process	pattern specification process
GO:0010073	Biological Process	meristem maintenance
GO:0010449	Biological Process	root meristem growth
GO:0019827	Biological Process	stem cell population maintenance
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 567 aa Download sequence Send to blast
MNNNWLSFPL SPSHSSLPPN DLQATQYHHF PLGLVNQNIE NPFQNHDWNL MNAQSSNEVP 60 KVADFLGVCK SENQTDLATP NEIQSNDSDN YLFTNNNLML MQNQVVTTTT NEYDQEKGNN 120 NNLQSLTLSM GSGKDSTCET SGDNSTNSAV EVAVPKRTSE TFGQRTSIYR GVTKHRWTGR 180 YEAHLWDNSC RREGQSRKGR QVYLGGYDKE EKAARSYDLA ALKYWGTSTT TNFPVSNYEK 240 EIDEMKHMTR QEFVASIRRK SSGFSRGASM YRGVTRHHQH GRWQARIGRV AGNKDLYLGT 300 FSTEEEAAEA YDIAAIKFRG LNAVTNFDMS RYDVKAILES NTLPIGGGAA KRLKEAQALE 360 SSRKREEMIA LNSSTFQYGT SSSSTSRLQP YPLMQHHHHQ YEQVQPLLTL QNHENSISQL 420 QNGYFQTQLE LHQQSGGSSS YVHQTSQNNN NSNNNNNNNN GLFYNGYFQN HIPGLYQGMM 480 NNMESSSSSS VIGNSNVGGG GSSGIYNNSG GLIGNNAAVE EFVPVKVDYD MPADGGYGGW 540 TAAAENMQTS NTADLFTMWN DYETREN

Sequence ? help Back to Top

Protein Sequence Length: 567 aa Download sequence Send to blast

MNNNWLSFPL SPSHSSLPPN DLQATQYHHF PLGLVNQNIE NPFQNHDWNL MNAQSSNEVP  60
KVADFLGVCK SENQTDLATP NEIQSNDSDN YLFTNNNLML MQNQVVTTTT NEYDQEKGNN  120
NNLQSLTLSM GSGKDSTCET SGDNSTNSAV EVAVPKRTSE TFGQRTSIYR GVTKHRWTGR  180
YEAHLWDNSC RREGQSRKGR QVYLGGYDKE EKAARSYDLA ALKYWGTSTT TNFPVSNYEK  240
EIDEMKHMTR QEFVASIRRK SSGFSRGASM YRGVTRHHQH GRWQARIGRV AGNKDLYLGT  300
FSTEEEAAEA YDIAAIKFRG LNAVTNFDMS RYDVKAILES NTLPIGGGAA KRLKEAQALE  360
SSRKREEMIA LNSSTFQYGT SSSSTSRLQP YPLMQHHHHQ YEQVQPLLTL QNHENSISQL  420
QNGYFQTQLE LHQQSGGSSS YVHQTSQNNN NSNNNNNNNN GLFYNGYFQN HIPGLYQGMM  480
NNMESSSSSS VIGNSNVGGG GSSGIYNNSG GLIGNNAAVE EFVPVKVDYD MPADGGYGGW  540
TAAAENMQTS NTADLFTMWN DYETREN

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269\|PubMed:15454085, ECO:0000269\|PubMed:15635403, ECO:0000269\|PubMed:16424342, ECO:0000269\|PubMed:20190735}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_004507106.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin accumulation. {ECO:0000269\|PubMed:15454085}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004507106.1	0.0	AP2-like ethylene-responsive transcription factor PLT2
Swissprot	Q5YGP7	0.0	PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2
TrEMBL	A0A1S2YMS5	0.0	A0A1S2YMS5_CICAR; AP2-like ethylene-responsive transcription factor PLT2
STRING	XP_004507106.1	0.0	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4942	31	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G51190.1	0.0	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Lee DK,Sieburth LE The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants. Plant Signal Behav, 2012. 7(6): p. 698-700 [PMID:22580686] Hong LW,Yan DW,Liu WC,Chen HG,Lu YT TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis. J. Exp. Bot., 2014. 65(1): p. 275-86 [PMID:24277277] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Zhao Q, et al. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche. J Integr Plant Biol, 2014. 56(12): p. 1151-63 [PMID:24831283] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Yang S, et al. The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance. Plant Cell, 2015. 27(6): p. 1670-80 [PMID:25991732] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Shinohara H,Mori A,Yasue N,Sumida K,Matsubayashi Y Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(14): p. 3897-902 [PMID:27001831] Ou Y, et al. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res., 2016. 26(6): p. 686-98 [PMID:27229312] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis . J Integr Plant Biol, 2017. 59(1): p. 30-43 [PMID:28074634] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]