PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_004515249.1
Organism
Cicer arietinum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer
Family HD-ZIP
Protein Properties Length: 722aa    MW: 80172.3 Da    PI: 6.4664
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_004515249.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.94e-192883156
                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                    +++ +++t++q+++Le++F+++++p++++r +L+++l L  rq+k+WFqNrR+++k
  XP_004515249.1 28 KKRYHRHTANQIQRLEAMFKECPHPDEKQRLQLSRELALAPRQIKFWFQNRRTQMK 83
                    678899***********************************************998 PP
2START183.71e-572274502206
                     HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetl 82 
                     +a  a++elv++ + ++p+W ks     + +n + + ++f+++++       ++ea+r+sgvv+m++ +lve ++d + +W e ++     a t+
  XP_004515249.1 227 IATNAMDELVRLLQTNDPLWIKSNtdgkDVLNLEAYERIFPKTNNrlknpnLRIEASRDSGVVIMNSLTLVEMFMDPN-KWMELFPtivtMARTI 320
                     56789********************999999**********9999*********************************.999999999999**** PP

                     EEECTT.....EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE CS
           START  83 evissg.....galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvd 171
                     evissg     g lqlm+ elq+lsplvp R+f+f+Ry+ q ++g w+ivdvS + + +++   +  R+++lpSg+ i++++ng+skvtw+ehv+
  XP_004515249.1 321 EVISSGimghsGSLQLMYEELQVLSPLVPiREFYFLRYCHQIEQGLWAIVDVSYEFPHDNQ-FTPQFRCHRLPSGCFIQDMPNGYSKVTWIEHVE 414
                     ************************************************************9.79999**************************** PP

                     --SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
           START 172 lkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                      +++ p h l+r ++ sg+a+ga +w+ tlqr ce+
  XP_004515249.1 415 IEDKNPiHRLYRNVIYSGVAFGAERWLTTLQRMCER 450
                     **********************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466894.6E-20485IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.0E-211387IPR009057Homeodomain-like
PROSITE profilePS5007117.6862585IPR001356Homeobox domain
SMARTSM003892.8E-172689IPR001356Homeobox domain
CDDcd000861.40E-172786No hitNo description
PfamPF000469.8E-172883IPR001356Homeobox domain
PROSITE patternPS0002706083IPR017970Homeobox, conserved site
PROSITE profilePS5084852.072217453IPR002913START domain
SuperFamilySSF559611.26E-39218451No hitNo description
CDDcd088753.18E-118221449No hitNo description
SMARTSM002341.8E-42226450IPR002913START domain
PfamPF018521.0E-49227450IPR002913START domain
Gene3DG3DSA:3.30.530.201.3E-7263416IPR023393START-like domain
SuperFamilySSF559613.97E-20483647No hitNo description
SuperFamilySSF559613.97E-20674711No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 722 aa     Download sequence    Send to blast
MEYHSGGSGS PGDHHHHHDG SSDSQRRKKR YHRHTANQIQ RLEAMFKECP HPDEKQRLQL  60
SRELALAPRQ IKFWFQNRRT QMKAQHERAD NCALRAENDK IRCENIAIRE ALKNVICPSC  120
GGPPINDDCY FDEQKLRIEN AQLKEELDRV SSIAAKYIGR PISQLPPVQP IHISSLDLSM  180
SSYGGQGLGG PSLDLDLLPG SSSSAMQNVP YQPACLSDME KSLMSDIATN AMDELVRLLQ  240
TNDPLWIKSN TDGKDVLNLE AYERIFPKTN NRLKNPNLRI EASRDSGVVI MNSLTLVEMF  300
MDPNKWMELF PTIVTMARTI EVISSGIMGH SGSLQLMYEE LQVLSPLVPI REFYFLRYCH  360
QIEQGLWAIV DVSYEFPHDN QFTPQFRCHR LPSGCFIQDM PNGYSKVTWI EHVEIEDKNP  420
IHRLYRNVIY SGVAFGAERW LTTLQRMCER LACLMVSGNS TRDLGGVIPS PEGXXXXXXX  480
XXXMVTNFCA SISASASHRW TTLSALNEIG VRVTVRKSTD PGQPNGVVLS AATTIWLPLP  540
PQTVFNFFKD ERKRSQWDVL SNGNAVQEVA HIANGSHPGN CISVLRAFNT SQNNMLILQE  600
SCVDSSGSLV VYCPVDLPAI NIAMSGEDPS YIPLLPSGFT ITSDGNQNDN NNNNNNNNVG  660
DGASTSSNTN LGGGSLITVA FQIMVSSLPS AKLNMESVAT VNGLIGETVQ HIKAALNCPS  720
SG
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_004515249.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004515249.10.0homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A1S2Z5450.0A0A1S2Z545_CICAR; homeobox-leucine zipper protein HDG11
STRINGXP_004515249.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]