PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009586687.1

Organism

Nicotiana tomentosiformis

Taxonomic ID

4098

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

GRF

Protein Properties

Length: 248aa MW: 27813.2 Da PI: 9.7989

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009586687.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	81.9	5.7e-26	147	190	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr+v++g+k+CErH+hrgrsrsrk++e XP_009586687.1 147 DPEPGRCRRTDGKKWRCSRDVVAGQKYCERHVHRGRSRSRKPVE 190 79***************************************987 PP
2	QLQ	46.3	1.3e-16	74	109	1	36
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiq 36 s+F+ Q+q+L+ Q+l+y++++a++PvPpeLl ++ XP_009586687.1 74 SYFSLGQWQELELQALIYRHFIAGAPVPPELLHLVK 109 789****************************98776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	9.4E-8	74	110	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	17.675	75	110	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	5.3E-11	76	108	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.141	147	191	IPR014977	WRC domain
Pfam	PF08879	6.5E-22	148	190	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 248 aa Download sequence Send to blast
MDFNLKQWRN QQHESEEQET PTSSAKIPRL HLDFDSVSAS DSDSALPLFV SEPTTKLSDS 60 TTTTPTKFPK MGSSYFSLGQ WQELELQALI YRHFIAGAPV PPELLHLVKK SIITSPSSYY 120 FSHPFQQYPH YQQTLMQSGY WGRAAMDPEP GRCRRTDGKK WRCSRDVVAG QKYCERHVHR 180 GRSRSRKPVE IPTPAINGGK LNTSTTVSHQ NLAKMAGHSA AAAAATHFSI SGPSPSIQTL 240 HLNQRYIS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:22419826}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:22419826}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009586687.1	0.0	PREDICTED: growth-regulating factor 3-like
Swissprot	Q9SJR5	3e-65	GRF3_ARATH; Growth-regulating factor 3
TrEMBL	A0A1S4ANY4	0.0	A0A1S4ANY4_TOBAC; growth-regulating factor 3-like isoform X1
STRING	XP_009586687.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3283	21	38

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36400.1	7e-60	growth-regulating factor 3

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Vercruyssen L, et al. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell, 2014. 26(1): p. 210-29 [PMID:24443518] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]