PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009589507.1
Organism
Nicotiana tomentosiformis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 1432aa    MW: 159783 Da    PI: 7.0121
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009589507.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.0004713411364223
                      EET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2    2 kCp..dCgksFsrksnLkrHirtH 23  
                      +Cp   Cgk F+++ +  +H+r+H
  XP_009589507.1 1341 RCPieGCGKKFTSHKYALVHQRVH 1364
                      69999*****************99 PP
2zf-C2H210.80.001614001426123
                      EEET..TTTEEESSHHHHHHHHHH..T CS
         zf-C2H2    1 ykCp..dCgksFsrksnLkrHirt..H 23  
                      ykC+   Cg +F+  s++ rH r+  H
  XP_009589507.1 1400 YKCKveGCGLTFRFVSDYSRHRRKtgH 1426
                      99*********************9777 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005451.5E-141757IPR003349JmjN domain
PROSITE profilePS5118313.731859IPR003349JmjN domain
PfamPF023752.2E-141952IPR003349JmjN domain
SMARTSM005583.9E-46287456IPR003347JmjC domain
SuperFamilySSF511974.39E-27288453No hitNo description
PROSITE profilePS5118434.323290456IPR003347JmjC domain
PfamPF023732.4E-36320439IPR003347JmjC domain
SMARTSM003551313171339IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.17513401369IPR007087Zinc finger, C2H2
SMARTSM003550.02413401364IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.05E-513401377No hitNo description
Gene3DG3DSA:3.30.160.601.9E-513411368IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028013421364IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.3E-913691394IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.53113701399IPR007087Zinc finger, C2H2
SMARTSM003550.002813701394IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028013721394IPR007087Zinc finger, C2H2
SuperFamilySSF576672.94E-1013801422No hitNo description
Gene3DG3DSA:3.30.160.601.4E-1013951423IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.2814001426IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.70214001431IPR007087Zinc finger, C2H2
PROSITE patternPS00028014021426IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009741Biological Processresponse to brassinosteroid
GO:0009826Biological Processunidimensional cell growth
GO:0033169Biological Processhistone H3-K9 demethylation
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0048579Biological Processnegative regulation of long-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 1432 aa     Download sequence    Send to blast
MVMKCVDIPE WLKGLPLAPE FRPTDTEFAD PIAYISKIEK EASAFGICKV IPPLPKPSKK  60
YVVHNLNKSL TKCPELGLNA NRGTSSTTSG EDEENVDGGE FRAVFTTRHQ ELGHSEKKKI  120
KREFGFHPLG AQKQVWQSGE VYTLEQFEAK SKNFARSQLG VVKEISPLVV EAMFWKRASE  180
DPIYVEYAND VPGSAFGEPE GLFHYFRRRR RRRKRTIPDR NSRRNSGYKN DEVGTSSSSA  240
DKSPRHSVET LSASLLTPPS KKITNSSLFR PKDCSNAGAM EGSAGWNLSN SPWNLQVIAR  300
SPGSLTRFMP DDIPGVTSPM VYIGMLFSWF AWHVEDHELH SLNFLHTGSP KTWYAVPGDY  360
AFSFEEVIRH HAYGGNTDRL AALTLLGEKT TLLSPEVVVA SGIPCCRLVQ NPGEFVVTFP  420
RAYHIGFSHG FNCGEAANFG TPQWLTVAKE AAVRRAAMNY LPMLSHQQLL YLLTMSFVSS  480
VPRSLLPGVR TSRLRDRQKE EKELLVKKAF LEDIEKENDL VKVLLQKSFS DNAVLWDVDI  540
LPSSGKEYEL HKHASVDASR GNDQSDSIDS QDLLDQMSLY MDNYSDFYVD DDVSCDFEID  600
SGTLPCIACG ILGFPFMTLV QPSKKAAEHL FPEDFQNKQD SGAVKHVESD CHSDLRGMIE  660
DYNRVDRMER NGGHYLNHDE VSLSSQPSES AVTPHEGQTS QSHNPSHTDN AALTSKIELQ  720
KEWDFCTSSV RPRIFCLEHA IQTEELLHTK GGANVLVICH SDFQKIRSHA TIVAEEIGTS  780
FKYNEISLAN ASQGHLSLID LAIVDEEQDK CTEDWTLKLN INLRHCVKVQ KNCPLKKLKH  840
ALTLGGLFSD STLSSESSSL KWQSRKVRSK RKSNNSTESP AFANVQIEKV LDSGSIVGRQ  900
NTRKGNITIR YSRKKYKSKA CSCAEVTRAF VDPFNGLTEE VLLTDAKTFG SSTLIRDENA  960
GTASSGERFF AAPEGKPGLH HEHEMLLVNR DQNGNLLVSQ EADLLVTSSI MVEFNEAQAE  1020
ICTTEKFSME EKTCHTNSNN RHAEHKTTAP EISGDTEVAH VNTPACTTIP VVRSTANNEN  1080
LREDQDMIES GIRNKSAHPT EADFEIDHHG EADKAIMTRS PVPVNSSGSC TDGPSRSCDE  1140
QIEDQSPEQS GSGSEASDNE ISDNSVEQKI QIDNADQGIA VSDHVTPVEE ASASAGSLKV  1200
TRETSSPKHS QSGDNISERH KKESNDDTSP IVSRPIAKSG GKRRRELELL TYDGCSIGGF  1260
VKSPCEGLRP RARKNVLGSR VDTKEPLEDK PMGKKVKTSL PSSITHKDKK EQRKGTHRCD  1320
LEGCRMSFQT KVELQLHKRN RCPIEGCGKK FTSHKYALVH QRVHENDRPL RCPWKGCTMT  1380
FKWAWARTEH LRVHTGERPY KCKVEGCGLT FRFVSDYSRH RRKTGHYVEA AN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ip0_A2e-55276470148346Transcription factor jumonji (Jmj) family protein
6ip4_A2e-55276470148346Arabidopsis JMJ13
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1206212RRRRRRR
2206214RRRRRRRKR
3207214RRRRRRKR
4208214RRRRRKR
Functional Description ? help Back to Top
Source Description
UniProtActs probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19946624}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009589507.10.0PREDICTED: probable lysine-specific demethylase ELF6
SwissprotQ6BDA00.0ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBLA0A1S3ZCI20.0A0A1S3ZCI2_TOBAC; lysine-specific demethylase SE14
STRINGXP_009589507.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA48351721
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G04240.10.0C2H2 family protein
Publications ? help Back to Top
  1. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Crevillén P, et al.
    Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.
    Nature, 2014. 515(7528): p. 587-90
    [PMID:25219852]
  4. Yang H,Howard M,Dean C
    Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74
    [PMID:27482092]