PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009763883.1

Organism

Nicotiana sylvestris

Taxonomic ID

4096

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

CAMTA

Protein Properties

Length: 1102aa MW: 123588 Da PI: 6.0816

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009763883.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	182.4	5.2e-57	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqr 96 l+ ++rwl++ ei++iL+n++k++++ e+++rp+sgsl+L++rk++ryfrkDG+sw+kkkdgktv+E+he+LK g+++vl+cyYah+een++fqr XP_009763883.1 20 LEAQHRWLRPAEICEILKNYQKFRIAPEPPNRPPSGSLFLFDRKVLRYFRKDGHSWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEENENFQR 114 5679***************************************************************************************** PP CG-1 97 rcywlLeeelekivlvhylevk 118 r+yw+Leee+++ivlvhy+evk XP_009763883.1 115 RSYWMLEEEMSHIVLVHYREVK 136 *****************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	83.558	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	1.9E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	3.7E-50	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	5.3E-4	516	599	IPR013783	Immunoglobulin-like fold
SuperFamily	SSF81296	9.57E-16	517	601	IPR014756	Immunoglobulin E-set
Pfam	PF01833	4.6E-4	517	593	IPR002909	IPT domain
CDD	cd00204	4.75E-12	699	808	No hit	No description
PROSITE profile	PS50297	17.582	699	821	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	1.8E-17	700	813	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	1.48E-16	704	811	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	6.8E-8	721	812	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	8.576	749	782	IPR002110	Ankyrin repeat
SMART	SM00248	1.9	749	779	IPR002110	Ankyrin repeat
SMART	SM00248	120	789	818	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	3.45E-7	918	975	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	50	924	946	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.346	926	954	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.18	927	945	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0042	947	969	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.285	948	972	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	5.0E-4	950	969	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1102 aa Download sequence Send to blast
MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF 60 DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML 120 EEEMSHIVLV HYREVKGNRT NFSRTREPQE ATPRFQETDE DVHSSEVDSS ASTKFYPNGY 180 QVNSQVTDAT SLSSAQASEY EDAESAYNQH PTSGFHSFLD AQPSMMQKAG ESLPVPYHPI 240 PFSNDHQVQF AGSSDMDFFS SAPGNKSRNT ANTYIPSRNL DFPSWETISV NNPAAYQSYH 300 FQPSSQSGAN NMTHEQGSTT MGQVFLNDFK KQGQNRIDSL GDWQTSEGDA AFISKWSMDQ 360 KLNPNLASDH TIRSSAAYNV ELHNSLEASH ILPSHQDKHP MQNELPSQLS DANVGGSLNA 420 ELDHNLSIGV RTDHSSLKQP LLDGVLREGL KKLDSFDRWM SKELEDVSEP HMQSNSSSYW 480 DNVGDDDGVD NSTIASQVQL DTYMLSPSLS QDQFFSIIDF SPSWAFAGSE IKVLITGKFL 540 KSQPEVEKWA CMFGELEVPA EVIADGVLRC HTPNQKVGRV PFYITCSNRL ACSEVREFEF 600 RVSESQDVDV ANSCSSSESL LHMRFGKLLS LESTVSLSSP PRSEDDVSNV CSKINSLLKE 660 DDNEWEEMLN LTYENNFMAE KVKDQLLQKL LKEKLRVWLL QKVAEGGKGP NVLDEGGQGV 720 LHFAAALGYD WAIPPTIAAG VSVNFRDVNG WTALHWAASY GRERTVGFLI ISLGAAPGAL 780 TDPTPKHPSG RTPADLASSN GHKGIAGYLA ESSLSSHLSS LELKEMKQGE TVQPFGEAVQ 840 TVSERSATPA WDGDWPHGVS LKDSLAAVRN ATQAAARIHQ VFRVQSFQRK QLKEHGGSEF 900 GLSDEHALSL LALKTNKAGQ HDEPVHTAAV RIQNKFRSWK GRRDYLLIRQ RIIKIQAHVR 960 GHQVRNKYKN IIWSVGILEK VILRWRRKGS GLRGFKPEAT LTEGSNMQDR PVQEDDYDFL 1020 KEGRKQTEQR LQKALARVKS MVQYPEARDQ YRRLLNVVSD MKDTTTTSDG APSNSGEAAD 1080 FGDDLIDLDD LLDDDTFMST AP

Sequence ? help Back to Top

Protein Sequence Length: 1102 aa Download sequence Send to blast

MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF  60
DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML  120
EEEMSHIVLV HYREVKGNRT NFSRTREPQE ATPRFQETDE DVHSSEVDSS ASTKFYPNGY  180
QVNSQVTDAT SLSSAQASEY EDAESAYNQH PTSGFHSFLD AQPSMMQKAG ESLPVPYHPI  240
PFSNDHQVQF AGSSDMDFFS SAPGNKSRNT ANTYIPSRNL DFPSWETISV NNPAAYQSYH  300
FQPSSQSGAN NMTHEQGSTT MGQVFLNDFK KQGQNRIDSL GDWQTSEGDA AFISKWSMDQ  360
KLNPNLASDH TIRSSAAYNV ELHNSLEASH ILPSHQDKHP MQNELPSQLS DANVGGSLNA  420
ELDHNLSIGV RTDHSSLKQP LLDGVLREGL KKLDSFDRWM SKELEDVSEP HMQSNSSSYW  480
DNVGDDDGVD NSTIASQVQL DTYMLSPSLS QDQFFSIIDF SPSWAFAGSE IKVLITGKFL  540
KSQPEVEKWA CMFGELEVPA EVIADGVLRC HTPNQKVGRV PFYITCSNRL ACSEVREFEF  600
RVSESQDVDV ANSCSSSESL LHMRFGKLLS LESTVSLSSP PRSEDDVSNV CSKINSLLKE  660
DDNEWEEMLN LTYENNFMAE KVKDQLLQKL LKEKLRVWLL QKVAEGGKGP NVLDEGGQGV  720
LHFAAALGYD WAIPPTIAAG VSVNFRDVNG WTALHWAASY GRERTVGFLI ISLGAAPGAL  780
TDPTPKHPSG RTPADLASSN GHKGIAGYLA ESSLSSHLSS LELKEMKQGE TVQPFGEAVQ  840
TVSERSATPA WDGDWPHGVS LKDSLAAVRN ATQAAARIHQ VFRVQSFQRK QLKEHGGSEF  900
GLSDEHALSL LALKTNKAGQ HDEPVHTAAV RIQNKFRSWK GRRDYLLIRQ RIIKIQAHVR  960
GHQVRNKYKN IIWSVGILEK VILRWRRKGS GLRGFKPEAT LTEGSNMQDR PVQEDDYDFL  1020
KEGRKQTEQR LQKALARVKS MVQYPEARDQ YRRLLNVVSD MKDTTTTSDG APSNSGEAAD  1080
FGDDLIDLDD LLDDDTFMST AP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF253511	0.0	AF253511.1 Nicotiana tabacum anther ethylene-upregulated protein ER1 (ER1) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009763883.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like isoform X2
Refseq	XP_016478077.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like isoform X2
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A1S4AMX5	0.0	A0A1S4AMX5_TOBAC; calmodulin-binding transcription activator 3-like isoform X2
TrEMBL	A0A1U7VBZ1	0.0	A0A1U7VBZ1_NICSY; calmodulin-binding transcription activator 3-like isoform X2
STRING	XP_009763882.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]