PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009765922.1
Organism
Nicotiana sylvestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 1423aa    MW: 158601 Da    PI: 6.8774
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009765922.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.0004713301353223
                      EET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2    2 kCp..dCgksFsrksnLkrHirtH 23  
                      +Cp   Cgk F+++ +  +H+r+H
  XP_009765922.1 1330 RCPieGCGKKFTSHKYALVHQRVH 1353
                      69999*****************99 PP
2zf-C2H210.80.001513891415123
                      EEET..TTTEEESSHHHHHHHHHH..T CS
         zf-C2H2    1 ykCp..dCgksFsrksnLkrHirt..H 23  
                      ykC+   Cg +F+  s++ rH r+  H
  XP_009765922.1 1389 YKCKveGCGLTFRFVSDYSRHRRKtgH 1415
                      99*********************9777 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005451.5E-141757IPR003349JmjN domain
PROSITE profilePS5118313.731859IPR003349JmjN domain
PfamPF023752.1E-141952IPR003349JmjN domain
SMARTSM005583.1E-46287456IPR003347JmjC domain
SuperFamilySSF511975.49E-28288453No hitNo description
PROSITE profilePS5118434.695290456IPR003347JmjC domain
PfamPF023734.4E-36320439IPR003347JmjC domain
SMARTSM003551313061328IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.05E-513291366No hitNo description
PROSITE profilePS5015712.17513291358IPR007087Zinc finger, C2H2
SMARTSM003550.02413291353IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.9E-513301357IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028013311353IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.3E-913581383IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.53113591388IPR007087Zinc finger, C2H2
SMARTSM003550.002813591383IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028013611383IPR007087Zinc finger, C2H2
SuperFamilySSF576672.1E-1013691411No hitNo description
Gene3DG3DSA:3.30.160.601.1E-1013841412IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.70213891420IPR007087Zinc finger, C2H2
SMARTSM003550.2813891415IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028013911415IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009741Biological Processresponse to brassinosteroid
GO:0009826Biological Processunidimensional cell growth
GO:0033169Biological Processhistone H3-K9 demethylation
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0048579Biological Processnegative regulation of long-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 1423 aa     Download sequence    Send to blast
MVMKCVDIPE WLKRLPLAPE FRPTDTEFAD PIAYISKIEK EASAFGICKV IPPLPKPSKK  60
YVVHNLNKSL SKCPELGLNA NRDTSSTTSG EDEGNVDGGE FRAVFTTRHQ ELGRSEKKKI  120
KREFGFQILG AQKQVWQSGE VYTLEQFEAK SKNFARSQLG VVKELSPLVV EAMFWKRASE  180
DPIYVEYAND VPGSAFGDPE GHFHYFRRRR RRGKRTIPDR NRRRNSSYKN DGVGTSGNSA  240
DKSPCHSVET RSASLLTPPS KKITNSSLFR PKDCSNAGAM EGSAGWNLSN SPWNLQVIAR  300
SPGSLTRFMP DDIPGVTSPM VYIGMLFSWF AWHVEDHELH SLNFLHTGSP KTWYAVPGDY  360
AFNFEEVIRH HAYGGNTDRL AALTLLGEKT TLLSPEVVVA SGIPCCRLVQ NPGEFVVTFP  420
RAYHIGFSHG FNCGEAANFG TPQWLTVAKE AAVRRAAMNY LPMLSHQQLL YLLTMSFVSS  480
VPRSLLPGVR TSRLRDRQKE EKELLVKKAF LEDIEKENDL VKVLLQKSFS DNAVLWDVDM  540
LPSSGKESEL HKHASVDASR GNDQSDNIDS QDLLDQMSLY MDNYSDFYVD DDVSCDFEVD  600
SGTLPCIACG ILGFPFMALV QPSKKAAEHL FPEDFQNKQD SGAVKHVESD CHSDLRGMIE  660
DYNRVDRMER NGGHFLNHDE VSLSSQPSES VVTPHEGQTS QSHNPSHTDN AALTSKVELE  720
KEWDFCRSFV RPRIFCLEHA IQTEELLHAK GGANVLVICH SDFQKISSHA TIVAEEIGTT  780
FKYNEITLAN ASQGHLSLID LAIVDEEQDK CTEDWTLKLN INLRHCVKVQ KNCPLKKLKH  840
ALTLGGLFSD STLSSESLSL KWQSRKVRSK KKSNNSTESP PFANVQIEKV LDSGSIVGRQ  900
STRKGNITIQ YSRKKYKSKA CSCAEVTSAF VDPFNALTEE VLLTDAKTLG SSTLIRDENA  960
GTASSGESCF AASEGKPGLH HEHEMLLVNR DQNGNLLESQ EADLLVTSSV MVEFSEAQAE  1020
MCTTEKFSME EKTCHTNSNN CHAEHKTTAP EISGETEVAH VNTPACTTIP VVQSTANNEN  1080
LRENQDTTES GIRNKSAHLT EADFERDHHG EADKTIMTRS PVPVNSSGSC TDGPSRSCDE  1140
QIEDQSPEQS GSGDEASDNE TSDNSVEQKI QIDNADQGIA VSDHVTPIEE ASTSAGSLKV  1200
TRETSSPKHS QSGDNISERH KKESNDDTSP IVSRPIAKSG GKRRRELELL TYDGCSIGGF  1260
VKSPCEGLRP RARKNVLGSR VDTKEPLEDK SMGKKVKTSL QRKGTHRCDL EGCRMSFQTK  1320
VELQLHKRNR CPIEGCGKKF TSHKYALVHQ RVHENDRPLR CPWKGCTMTF KWAWARTEHL  1380
RVHTGERPYK CKVEGCGLTF RFVSDYSRHR RKTGHYVEAA NRC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ip0_A2e-55276470148346Transcription factor jumonji (Jmj) family protein
6ip4_A2e-55276470148346Arabidopsis JMJ13
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1206214RRRRRRGKR
2207223RRRRRGKRTIPDRNRRR
Functional Description ? help Back to Top
Source Description
UniProtActs probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19946624}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009765922.10.0PREDICTED: lysine-specific demethylase SE14
SwissprotQ6BDA00.0ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBLA0A1U7VCW50.0A0A1U7VCW5_NICSY; lysine-specific demethylase SE14
STRINGXP_009765922.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA48351721
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G04240.10.0C2H2 family protein
Publications ? help Back to Top
  1. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Crevillén P, et al.
    Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.
    Nature, 2014. 515(7528): p. 587-90
    [PMID:25219852]
  4. Yang H,Howard M,Dean C
    Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74
    [PMID:27482092]