PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009799136.1

Organism

Nicotiana sylvestris

Taxonomic ID

4096

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

AP2

Protein Properties

Length: 575aa MW: 64384.7 Da PI: 6.9968

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009799136.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	44	5.7e-14	208	267	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + g ++ ++++lg ++ +e+Aa+ ++ a++k++g XP_009799136.1 208 SIYRGVTRHRWTGRYEAHLWDnSCRrEGqsRKgRQVYLGGYDKEEKAARSYDLAALKYWG 267 57*****************666664477446***********************98 PP
2	AP2	50.7	4.4e-16	312	361	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GV+++++ grW A+I + +k +lg+fgt+eeAa+a++ a+ k++g XP_009799136.1 312 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTEEEAAEAYDVAAIKFRG 361 9*************988532...5**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	3.07E-16	208	277	IPR016177	DNA-binding domain
Pfam	PF00847	5.1E-11	208	267	IPR001471	AP2/ERF domain
CDD	cd00018	1.72E-21	208	277	No hit	No description
PROSITE profile	PS51032	18.953	209	275	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	9.6E-15	209	275	IPR001471	AP2/ERF domain
SMART	SM00380	7.4E-29	209	281	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.6E-5	210	221	IPR001471	AP2/ERF domain
CDD	cd00018	1.64E-23	310	369	No hit	No description
SuperFamily	SSF54171	9.81E-18	310	370	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	1.7E-17	311	369	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	18.979	311	369	IPR001471	AP2/ERF domain
SMART	SM00380	8.1E-31	311	375	IPR001471	AP2/ERF domain
Pfam	PF00847	2.9E-11	312	361	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.6E-5	351	371	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 575 aa Download sequence Send to blast
MKEWDKLRDS QTEGRKHVQE LIHLAQKFKA QHIVKEICKN IMGSMNSNNW LSFHLSPHLQ 60 TTESHSLGSV AETIDNPFQN QEWNFTDTQG GNEVPKVADF FGVSKSGHES ELVSYSKIQA 120 NDNSDYPFPN TNLMPMQNVT YDLQENAWNM QSLTLSMGSG KSSTSETSAS PNANATARAS 180 STSGENSNTS IVEAAPRRTS DTFGQRTSIY RGVTRHRWTG RYEAHLWDNS CRREGQSRKG 240 RQVYLGGYDK EEKAARSYDL AALKYWGTST TTNFPINNYE KEVEEMKHMT RQESIASIRR 300 KSTGFSRGAS MYRGVTRHHQ HGRWQARIGR VAGNKDLYLG TFGTEEEAAE AYDVAAIKFR 360 GLCAVTNFEM NRYDVKAILE SNTLPIGGGA AKRLKEAQAF ESSRKRDQEM ISLNSTTTFH 420 QYENSNNSGV AFQTYPLMQQ QPLLSTLQNQ DFSSQFHHSY IQTQLQLHHQ QSHQMYNDYF 480 QSNNPVFLHG LMNNMGSSSS VMNNNGGSSS GSYSNGGYLD NTTGIGMTSN SPSGGGSAHE 540 EIAMVKVDYD MPYTGWSGES SVQESNPGAF TMWND

Sequence ? help Back to Top

Protein Sequence Length: 575 aa Download sequence Send to blast

MKEWDKLRDS QTEGRKHVQE LIHLAQKFKA QHIVKEICKN IMGSMNSNNW LSFHLSPHLQ  60
TTESHSLGSV AETIDNPFQN QEWNFTDTQG GNEVPKVADF FGVSKSGHES ELVSYSKIQA  120
NDNSDYPFPN TNLMPMQNVT YDLQENAWNM QSLTLSMGSG KSSTSETSAS PNANATARAS  180
STSGENSNTS IVEAAPRRTS DTFGQRTSIY RGVTRHRWTG RYEAHLWDNS CRREGQSRKG  240
RQVYLGGYDK EEKAARSYDL AALKYWGTST TTNFPINNYE KEVEEMKHMT RQESIASIRR  300
KSTGFSRGAS MYRGVTRHHQ HGRWQARIGR VAGNKDLYLG TFGTEEEAAE AYDVAAIKFR  360
GLCAVTNFEM NRYDVKAILE SNTLPIGGGA AKRLKEAQAF ESSRKRDQEM ISLNSTTTFH  420
QYENSNNSGV AFQTYPLMQQ QPLLSTLQNQ DFSSQFHHSY IQTQLQLHHQ QSHQMYNDYF  480
QSNNPVFLHG LMNNMGSSSS VMNNNGGSSS GSYSNGGYLD NTTGIGMTSN SPSGGGSAHE  540
EIAMVKVDYD MPYTGWSGES SVQESNPGAF TMWND

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269\|PubMed:15454085, ECO:0000269\|PubMed:15635403, ECO:0000269\|PubMed:16424342, ECO:0000269\|PubMed:20190735}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin accumulation. {ECO:0000269\|PubMed:15454085}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009799136.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor PLT2 isoform X2
Swissprot	Q5YGP7	0.0	PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2
TrEMBL	A0A1U7YB09	0.0	A0A1U7YB09_NICSY; AP2-like ethylene-responsive transcription factor PLT2 isoform X2
STRING	XP_009799135.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G51190.1	0.0	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Lee DK,Sieburth LE The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants. Plant Signal Behav, 2012. 7(6): p. 698-700 [PMID:22580686] Hong LW,Yan DW,Liu WC,Chen HG,Lu YT TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis. J. Exp. Bot., 2014. 65(1): p. 275-86 [PMID:24277277] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Zhao Q, et al. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche. J Integr Plant Biol, 2014. 56(12): p. 1151-63 [PMID:24831283] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Yang S, et al. The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance. Plant Cell, 2015. 27(6): p. 1670-80 [PMID:25991732] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Shinohara H,Mori A,Yasue N,Sumida K,Matsubayashi Y Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(14): p. 3897-902 [PMID:27001831] Ou Y, et al. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res., 2016. 26(6): p. 686-98 [PMID:27229312] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis . J Integr Plant Biol, 2017. 59(1): p. 30-43 [PMID:28074634] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]