PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010093589.1
Organism
Morus notabilis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family MYB
Protein Properties Length: 425aa    MW: 47034.3 Da    PI: 6.939
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010093589.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding506.6e-161461148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g+WT+eEd++lvd+++ +  g W++ +++ g+ R++k+c++rw +yl
   XP_010093589.1 14 KGAWTEEEDKKLVDYIANHSEGGWRSLPQKAGLLRCGKSCRLRWANYL 61
                     79******************************99************97 PP
2Myb_DNA-binding59.11e-1867110146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      rg +++eE+e +++++ +lG++ W+tIa++++ +Rt++++k++w++
   XP_010093589.1  67 RGEFSPEEEETIIKLHSELGNK-WSTIAKHLP-RRTDNEIKNHWNT 110
                      899*******************.*********.***********97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129413.017961IPR017930Myb domain
SuperFamilySSF466891.65E-2811108IPR009057Homeodomain-like
SMARTSM007171.6E-101363IPR001005SANT/Myb domain
PfamPF002496.5E-141461IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.8E-211568IPR009057Homeodomain-like
CDDcd001675.27E-81661No hitNo description
PROSITE profilePS5129427.7462116IPR017930Myb domain
SMARTSM007172.5E-1766114IPR001005SANT/Myb domain
PfamPF002498.4E-1767110IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.2E-2669115IPR009057Homeodomain-like
CDDcd001672.21E-1269112No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 425 aa     Download sequence    Send to blast
MGRTSCCSIE GLKKGAWTEE EDKKLVDYIA NHSEGGWRSL PQKAGLLRCG KSCRLRWANY  60
LRPGIKRGEF SPEEEETIIK LHSELGNKWS TIAKHLPRRT DNEIKNHWNT RLKRRAAETR  120
IDRNFARNPE PPEGGNNNTE AETSARKEEL KDSGKFIGPI STSSKLLNKA AAKLRLSGSL  180
ASFLSQQIGK SKSLEGSSVP STSSAHLLNK MATNLSSSSP RSHSLGAIKA IFSKSLDDNN  240
AAISTITTNN NSPSENIGIG KCNSLVESPD QSENATQVSS PTRTYSASAR LLNRMATKFA  300
LTHHRPHLVL GDWKTVSCNS PDQESTRTES LVSVPSLWMV DSPQEMSHFD ETTQISYRDM  360
AVEADQDQAF LMEIADDHHQ KERDCDSYDG CSTPVEAIVG DLEAANNWNI DCFYIDDLFN  420
SAKSQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-2491152107B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtMajor regulator of short-chained aliphatic glucosinolates (GLSs) biosynthesis. Together with MYB29/HAG3 and MYB76/HAG2, promotes aliphatic glucosinolate biosynthesis but represses indolic glucosinolate biosynthesis. Prevents insect performance (e.g. lepidopteran insect Mamestra brassicae and Spodoptera exigua) by promoting glucosinolates. {ECO:0000269|PubMed:17420480, ECO:0000269|PubMed:17521412, ECO:0000269|PubMed:18042203, ECO:0000269|PubMed:18446225, ECO:0000269|PubMed:20348214, ECO:0000269|PubMed:23580754, ECO:0000269|PubMed:23792303, ECO:0000269|PubMed:23943862}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010093589.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by glucose, gibberellic acid (GA), jasmonic acid (JA) and salicylic acid (SA). Transiently induced in inflorescence by mechanical stimuli such as touch or wounding, including herbivory-wounding. Up-regulated by sulfur-deficient stress. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17521412, ECO:0000269|PubMed:23115560, ECO:0000269|PubMed:23792303}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010093589.10.0transcription factor MYB34
SwissprotQ9SPG23e-61MYB28_ARATH; Transcription factor MYB28
TrEMBLW9QTW60.0W9QTW6_9ROSA; Transcription factor
STRINGXP_010093589.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF2559633
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G61420.25e-62myb domain protein 28
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Kim K,Jiang K,Teng SL,Feldman LJ,Huang H
    Using biologically interrelated experiments to identify pathway genes in Arabidopsis.
    Bioinformatics, 2012. 28(6): p. 815-22
    [PMID:22271267]
  3. Augustine R,Majee M,Gershenzon J,Bisht NC
    Four genes encoding MYB28, a major transcriptional regulator of the aliphatic glucosinolate pathway, are differentially expressed in the allopolyploid Brassica juncea.
    J. Exp. Bot., 2013. 64(16): p. 4907-21
    [PMID:24043856]
  4. Guo R, et al.
    Jasmonic acid and glucose synergistically modulate the accumulation of glucosinolates in Arabidopsis thaliana.
    J. Exp. Bot., 2013. 64(18): p. 5707-19
    [PMID:24151308]
  5. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  6. Li F, et al.
    Genome-wide association study dissects the genetic architecture of seed weight and seed quality in rapeseed (Brassica napus L.).
    DNA Res., 2014. 21(4): p. 355-67
    [PMID:24510440]
  7. Frerigmann H,Gigolashvili T
    Update on the role of R2R3-MYBs in the regulation of glucosinolates upon sulfur deficiency.
    Front Plant Sci, 2014. 5: p. 626
    [PMID:25426131]
  8. Burow M, et al.
    The Glucosinolate Biosynthetic Gene AOP2 Mediates Feed-back Regulation of Jasmonic Acid Signaling in Arabidopsis.
    Mol Plant, 2015. 8(8): p. 1201-12
    [PMID:25758208]
  9. Martínez-Ballesta M, et al.
    The impact of the absence of aliphatic glucosinolates on water transport under salt stress in Arabidopsis thaliana.
    Front Plant Sci, 2015. 6: p. 524
    [PMID:26236322]
  10. Seo MS, et al.
    Functional analysis of three BrMYB28 transcription factors controlling the biosynthesis of glucosinolates in Brassica rapa.
    Plant Mol. Biol., 2016. 90(4-5): p. 503-16
    [PMID:26820138]
  11. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  12. Mostafa I, et al.
    New nodes and edges in the glucosinolate molecular network revealed by proteomics and metabolomics of Arabidopsis myb28/29 and cyp79B2/B3 glucosinolate mutants.
    J Proteomics, 2016. 138: p. 1-19
    [PMID:26915584]
  13. Smith JD,Woldemariam MG,Mescher MC,Jander G,De Moraes CM
    Glucosinolates from Host Plants Influence Growth of the Parasitic Plant Cuscuta gronovii and Its Susceptibility to Aphid Feeding.
    Plant Physiol., 2016. 172(1): p. 181-97
    [PMID:27482077]
  14. Aarabi F, et al.
    Sulfur deficiency-induced repressor proteins optimize glucosinolate biosynthesis in plants.
    Sci Adv, 2016. 2(10): p. e1601087
    [PMID:27730214]
  15. Mostafa I, et al.
    Membrane Proteomics of Arabidopsis Glucosinolate Mutants cyp79B2/B3 and myb28/29.
    Front Plant Sci, 2017. 8: p. 534
    [PMID:28443122]
  16. Simon MK,Skinner DJ,Gallagher TL,Gasser CS
    Integument Development in Arabidopsis Depends on Interaction of YABBY Protein INNER NO OUTER with Coactivators and Corepressors.
    Genetics, 2017. 207(4): p. 1489-1500
    [PMID:28971961]
  17. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]