PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010111484.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family E2F/DP
Protein Properties Length: 352aa    MW: 39274.1 Da    PI: 10.0392
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010111484.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.41.2e-23134214371
         E2F_TDP   3 eksLrlltqkflklleksee.givtlnevakeLvse...............dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     + +Lr+++ +   +++k e+ g++t++eva+e++se               d+kn+rRR+YD+lNVL+al++i++ +k+ei+wkg
  XP_010111484.1 134 GGGLRQFSVM---VCKKLESkGRTTYSEVADEIISElngmrndttvsldefDEKNIRRRVYDALNVLMALEIITR-DKKEIQWKG 214
                     6799999999...****9999******************************************************.*******98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-37129218IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.6E-28132214IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.3E-21135214IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.94E-18135215IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF1440747.32E-21221341No hitNo description
SMARTSM011382.7E-9221340IPR014889Transcription factor DP, C-terminal
PfamPF087812.1E-10222284IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
MAHKGAFMIP IQYFVIAASG KLRNSLTLFW NHIDLIFRHP LLVKILLGNL KITAKDSNWS  60
IMGEEYLKES FNGLGEKHST AESSLTLLFD SGNLSTACEN EKTPKHKASR DNADSAVVES  120
SNAAKKKRAS RINGGGLRQF SVMVCKKLES KGRTTYSEVA DEIISELNGM RNDTTVSLDE  180
FDEKNIRRRV YDALNVLMAL EIITRDKKEI QWKGLPSTDI KELEELKAVR VKLVNMIRKK  240
AAYLNDLEEQ IAGLQCLISR NKQLLNCGNS PVEGFSLPFL LVQSPNVVLG NGSTPFSLHD  300
DAYILKLLRR HQLPVIRPVS RSSSSALSSS SSGIVSRATK PFSWNSEKHA QR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B8e-28133217891PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding and the transactivation activities of E2F proteins after heterodimerization. The complex DPA/E2FA promotes cell division and acts as a regulator of the endocycle. Positively regulates the activity of S phase-specific genes. {ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010111484.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor ERF114. {ECO:0000269|PubMed:23616605}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024031258.10.0transcription factor-like protein DPA isoform X1
SwissprotQ9FNY22e-65DPB_ARATH; Transcription factor-like protein DPB
SwissprotQ9FNY31e-65DPA_ARATH; Transcription factor-like protein DPA
TrEMBLW9SWI60.0W9SWI6_9ROSA; Transcription factor-like protein DPB
STRINGXP_010111484.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02470.39e-68Transcription factor DP