PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_010530031.1

Organism

Tarenaya hassleriana

Taxonomic ID

28532

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

bHLH

Protein Properties

Length: 653aa MW: 70654.9 Da PI: 4.9943

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010530031.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	39.3	1.2e-12	477	522	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L XP_010530031.1 477 NHVEAERQRREKLNQRFYSLRAVVPNV-----SKMDKASLLGDAISYINEL 522 799*********************6.....5*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	8.4E-53	72	262	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.282	473	522	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.99E-15	476	527	No hit	No description
SuperFamily	SSF47459	1.27E-18	476	544	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.1E-18	477	543	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.4E-10	477	522	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.4E-17	479	528	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 653 aa Download sequence Send to blast
MTDYRLNRST NGTTASINLW TADDDASVME AFVSSDHSAL WPPAPPAEQL SAGGDHPQQP 60 AAAQSRLNED TLQQRLQALI EGARETWTYA IYWQLSYDSI AGGGDGEGTA FLGWGDGYYK 120 GEEDKGKSKK RCSSVNAVEQ EHRKRVIREL NALISGGAVA GAADDAGDEE VTDTEWFFLV 180 SMTQSFLNGT GLPGQAFLHC RTIWLSGSGA LAGSGCERAQ QGQIYGLRTL VCIPSDNGVV 240 ELGSTDVIQQ SSDLMEKVNT LFNFNNGGGE AGSWTFNLNP DEGENDPTLW ITEPTTRIDS 300 GHVIPTAAIN NGNSNSNSNS HQFPKPGHFE NGSSVENPGQ NPQSSSLDRN LNLSSSGLNQ 360 NGNFSDGSRP KSGEILNFCG NKNGNGTGFS GQTSFAAAEN NKKRSPVSKG SNNDEGMLSF 420 TCGVVLPSSA AKSGDSDHSD VEASVAKEAD SSRIVEPEKK PRKRGRKPAN GREEPLNHVE 480 AERQRREKLN QRFYSLRAVV PNVSKMDKAS LLGDAISYIN ELKSKLQEAE SDKEDLQKQL 540 NELNKEGSGK DSRPQSSKDR KGLNQDSGPA MEMEIDVKII GWDVMIRIQC SKKNHPGAKF 600 MEALKELDLE VNHASLSVVN DLMIQQATVK MGNRFLTQDQ LKVALMAKVG ESS

Sequence ? help Back to Top

Protein Sequence Length: 653 aa Download sequence Send to blast

MTDYRLNRST NGTTASINLW TADDDASVME AFVSSDHSAL WPPAPPAEQL SAGGDHPQQP  60
AAAQSRLNED TLQQRLQALI EGARETWTYA IYWQLSYDSI AGGGDGEGTA FLGWGDGYYK  120
GEEDKGKSKK RCSSVNAVEQ EHRKRVIREL NALISGGAVA GAADDAGDEE VTDTEWFFLV  180
SMTQSFLNGT GLPGQAFLHC RTIWLSGSGA LAGSGCERAQ QGQIYGLRTL VCIPSDNGVV  240
ELGSTDVIQQ SSDLMEKVNT LFNFNNGGGE AGSWTFNLNP DEGENDPTLW ITEPTTRIDS  300
GHVIPTAAIN NGNSNSNSNS HQFPKPGHFE NGSSVENPGQ NPQSSSLDRN LNLSSSGLNQ  360
NGNFSDGSRP KSGEILNFCG NKNGNGTGFS GQTSFAAAEN NKKRSPVSKG SNNDEGMLSF  420
TCGVVLPSSA AKSGDSDHSD VEASVAKEAD SSRIVEPEKK PRKRGRKPAN GREEPLNHVE  480
AERQRREKLN QRFYSLRAVV PNVSKMDKAS LLGDAISYIN ELKSKLQEAE SDKEDLQKQL  540
NELNKEGSGK DSRPQSSKDR KGLNQDSGPA MEMEIDVKII GWDVMIRIQC SKKNHPGAKF  600
MEALKELDLE VNHASLSVVN DLMIQQATVK MGNRFLTQDQ LKVALMAKVG ESS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	5e-89	64	265	1	195	Transcription factor MYC3
4rqw_B	5e-89	64	265	1	195	Transcription factor MYC3
4rru_A	7e-89	14	258	1	227	Transcription factor MYC3
4rs9_A	5e-89	64	265	1	195	Transcription factor MYC3
4ywc_A	7e-89	14	258	1	227	Transcription factor MYC3
4ywc_B	7e-89	14	258	1	227	Transcription factor MYC3
4yz6_A	5e-89	64	265	1	195	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	458	466	KKPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. {ECO:0000269\|PubMed:21321051, ECO:0000269\|PubMed:21335373, ECO:0000269\|PubMed:23943862}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010530031.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV treatment. Not induced by jasmonic acid. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:21335373}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010530031.1	0.0	PREDICTED: transcription factor MYC4
Swissprot	O49687	0.0	MYC4_ARATH; Transcription factor MYC4
TrEMBL	E4MW10	0.0	E4MW10_EUTHA; mRNA, clone: RTFL01-05-E20
TrEMBL	V4L837	0.0	V4L837_EUTSA; Uncharacterized protein
STRING	XP_010530031.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1265	28	96

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17880.1	0.0	bHLH family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chico JM, et al. Repression of Jasmonate-Dependent Defenses by Shade Involves Differential Regulation of Protein Stability of MYC Transcription Factors and Their JAZ Repressors in Arabidopsis. Plant Cell, 2014. 26(5): p. 1967-1980 [PMID:24824488] Gasperini D, et al. Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth. PLoS Genet., 2015. 11(6): p. e1005300 [PMID:26070206] Qi T, et al. Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis. Plant Cell, 2015. 27(6): p. 1634-49 [PMID:26071420] de Torres Zabala M, et al. Novel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection. New Phytol., 2016. 209(3): p. 1120-34 [PMID:26428397] Yu J, et al. JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. J. Exp. Bot., 2016. 67(3): p. 751-62 [PMID:26547795] Chen X,Huang H,Qi T,Liu B,Song S New perspective of the bHLH-MYB complex in jasmonate-regulated plant fertility in arabidopsis. Plant Signal Behav, 2016. 11(2): p. e1135280 [PMID:26829586] Schmiesing A,Emonet A,Gouhier-Darimont C,Reymond P Arabidopsis MYC Transcription Factors Are the Target of Hormonal Salicylic Acid/Jasmonic Acid Cross Talk in Response to Pieris brassicae Egg Extract. Plant Physiol., 2016. 170(4): p. 2432-43 [PMID:26884488] Thatcher LF, et al. Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum. J. Exp. Bot., 2016. 67(8): p. 2367-86 [PMID:26896849] Gao C, et al. MYC2, MYC3, and MYC4 function redundantly in seed storage protein accumulation in Arabidopsis. Plant Physiol. Biochem., 2016. 108: p. 63-70 [PMID:27415132] Gimenez-Ibanez S, et al. JAZ2 controls stomata dynamics during bacterial invasion. New Phytol., 2017. 213(3): p. 1378-1392 [PMID:28005270] Lian TF,Xu YP,Li LF,Su XD Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA. Cell Rep, 2017. 19(7): p. 1334-1342 [PMID:28514654] Wang H, et al. The bHLH Transcription Factors MYC2, MYC3, and MYC4 Are Required for Jasmonate-Mediated Inhibition of Flowering in Arabidopsis. Mol Plant, 2017. 10(11): p. 1461-1464 [PMID:28827172] Song S, et al. MYC5 is Involved in Jasmonate-Regulated Plant Growth, Leaf Senescence and Defense Responses. Plant Cell Physiol., 2017. 58(10): p. 1752-1763 [PMID:29017003] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884]