PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_010538501.1

Organism

Tarenaya hassleriana

Taxonomic ID

28532

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

bHLH

Protein Properties

Length: 646aa MW: 69885 Da PI: 5.0546

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010538501.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.2	1.1e-11	470	515	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ A+ YI++L XP_010538501.1 470 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLIGDAISYISEL 515 799*********************6.....5**************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	8.8E-53	71	257	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	16.806	466	515	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	8.77E-18	469	533	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.82E-14	469	520	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.8E-17	470	535	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.3E-9	470	515	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.2E-15	472	521	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006952	Biological Process	defense response
GO:0009718	Biological Process	anthocyanin-containing compound biosynthetic process
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043425	Molecular Function	bHLH transcription factor binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 646 aa Download sequence Send to blast
MADYRQNQPT KGTTASINQW TTDDDASVME AFMGSDHSAL WPPATPHQQL SGGAHPQQPA 60 AAQSQFNEDT LQQRLQSLIE GAREPWTYAI FWQLSYDFPG GDGTALLGWG DGYYKGEEDK 120 GKSRKKCSSA SAAEQEHRKR VIRELNALIS GGEAVGAADD AGDEEVTDTE GFFLVSMTQS 180 FLNGTGLPGQ ASLNSRTIWL AGSGVLAGSG CERARQGQIY GLQTLVCIPS ENGVVELGST 240 EVIQQSSDLM EKVNTLFHFN DGGGEAGSWA FSLNPDEGEN DPALWISEPT TGIESGHVAP 300 TEAINNGNSN SNSNSNSHLF PKPGHFDNGG SSVENPGQNP QSDLNLSSSG LNQNGNYPDG 360 SRPKSGEILT SSEKRNGNGT GYSGQTSFMA GDSNKKRSPV SKGSNNEEGM LSFTCGVVIP 420 SAAAKSGDSD HSDVEASVAK EADSGRTVEP EKRPRKRGRK PANGREEPLN HVEAERQRRE 480 KLNQRFYALR AVVPNVSKMD KASLIGDAIS YISELKSKLQ TAESDKEELR QQLNKEESGK 540 DSRPQQRSKD RKGVITNQDS GLAIEMEIDV KIIGWDVMIR IQCGKKNHPG AKFMEALKDL 600 DLEVNHASLS VVNDLMIQQA TVKMGNRFFS QDQLKRALMA KVGEIQ

Sequence ? help Back to Top

Protein Sequence Length: 646 aa Download sequence Send to blast

MADYRQNQPT KGTTASINQW TTDDDASVME AFMGSDHSAL WPPATPHQQL SGGAHPQQPA  60
AAQSQFNEDT LQQRLQSLIE GAREPWTYAI FWQLSYDFPG GDGTALLGWG DGYYKGEEDK  120
GKSRKKCSSA SAAEQEHRKR VIRELNALIS GGEAVGAADD AGDEEVTDTE GFFLVSMTQS  180
FLNGTGLPGQ ASLNSRTIWL AGSGVLAGSG CERARQGQIY GLQTLVCIPS ENGVVELGST  240
EVIQQSSDLM EKVNTLFHFN DGGGEAGSWA FSLNPDEGEN DPALWISEPT TGIESGHVAP  300
TEAINNGNSN SNSNSNSHLF PKPGHFDNGG SSVENPGQNP QSDLNLSSSG LNQNGNYPDG  360
SRPKSGEILT SSEKRNGNGT GYSGQTSFMA GDSNKKRSPV SKGSNNEEGM LSFTCGVVIP  420
SAAAKSGDSD HSDVEASVAK EADSGRTVEP EKRPRKRGRK PANGREEPLN HVEAERQRRE  480
KLNQRFYALR AVVPNVSKMD KASLIGDAIS YISELKSKLQ TAESDKEELR QQLNKEESGK  540
DSRPQQRSKD RKGVITNQDS GLAIEMEIDV KIIGWDVMIR IQCGKKNHPG AKFMEALKDL  600
DLEVNHASLS VVNDLMIQQA TVKMGNRFFS QDQLKRALMA KVGEIQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rru_A	2e-91	14	253	1	227	Transcription factor MYC3
4ywc_A	2e-91	14	253	1	227	Transcription factor MYC3
4ywc_B	2e-91	14	253	1	227	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	451	459	KRPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. {ECO:0000269\|PubMed:21321051, ECO:0000269\|PubMed:21335373, ECO:0000269\|PubMed:23943862}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00086	PBM	Transfer from AT4G17880	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010538501.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV treatment. Not induced by jasmonic acid. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:21335373}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010538501.1	0.0	PREDICTED: transcription factor MYC4-like
Swissprot	O49687	0.0	MYC4_ARATH; Transcription factor MYC4
TrEMBL	E4MW10	0.0	E4MW10_EUTHA; mRNA, clone: RTFL01-05-E20
TrEMBL	V4L837	0.0	V4L837_EUTSA; Uncharacterized protein
STRING	XP_010538501.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1265	28	96

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17880.1	0.0	bHLH family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chico JM, et al. Repression of Jasmonate-Dependent Defenses by Shade Involves Differential Regulation of Protein Stability of MYC Transcription Factors and Their JAZ Repressors in Arabidopsis. Plant Cell, 2014. 26(5): p. 1967-1980 [PMID:24824488] Gasperini D, et al. Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth. PLoS Genet., 2015. 11(6): p. e1005300 [PMID:26070206] Qi T, et al. Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis. Plant Cell, 2015. 27(6): p. 1634-49 [PMID:26071420] de Torres Zabala M, et al. Novel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection. New Phytol., 2016. 209(3): p. 1120-34 [PMID:26428397] Yu J, et al. JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. J. Exp. Bot., 2016. 67(3): p. 751-62 [PMID:26547795] Chen X,Huang H,Qi T,Liu B,Song S New perspective of the bHLH-MYB complex in jasmonate-regulated plant fertility in arabidopsis. Plant Signal Behav, 2016. 11(2): p. e1135280 [PMID:26829586] Schmiesing A,Emonet A,Gouhier-Darimont C,Reymond P Arabidopsis MYC Transcription Factors Are the Target of Hormonal Salicylic Acid/Jasmonic Acid Cross Talk in Response to Pieris brassicae Egg Extract. Plant Physiol., 2016. 170(4): p. 2432-43 [PMID:26884488] Thatcher LF, et al. Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum. J. Exp. Bot., 2016. 67(8): p. 2367-86 [PMID:26896849] Gao C, et al. MYC2, MYC3, and MYC4 function redundantly in seed storage protein accumulation in Arabidopsis. Plant Physiol. Biochem., 2016. 108: p. 63-70 [PMID:27415132] Gimenez-Ibanez S, et al. JAZ2 controls stomata dynamics during bacterial invasion. New Phytol., 2017. 213(3): p. 1378-1392 [PMID:28005270] Lian TF,Xu YP,Li LF,Su XD Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA. Cell Rep, 2017. 19(7): p. 1334-1342 [PMID:28514654] Wang H, et al. The bHLH Transcription Factors MYC2, MYC3, and MYC4 Are Required for Jasmonate-Mediated Inhibition of Flowering in Arabidopsis. Mol Plant, 2017. 10(11): p. 1461-1464 [PMID:28827172] Song S, et al. MYC5 is Involved in Jasmonate-Regulated Plant Growth, Leaf Senescence and Defense Responses. Plant Cell Physiol., 2017. 58(10): p. 1752-1763 [PMID:29017003] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884]