PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010913427.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Arecales; Arecaceae; Arecoideae; Cocoseae; Elaeidinae; Elaeis
Family E2F/DP
Protein Properties Length: 398aa    MW: 44320.1 Da    PI: 9.5109
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010913427.1genomeOGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.83.7e-232085171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rk+ksL+ll+++f++l+ + + + v l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++w+g
  XP_010913427.1 20 RKQKSLGLLCSNFVSLYDRDDVESVGLDDAARRL---GV--ERRRIYDIVNVLESVGVLARKAKNRYSWIG 85
                    79****************9999************...**..****************************98 PP

2E2F_TDP79.33.4e-25160240171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     r+eksL+lltq+f+kl+ ++++++v+l+e+a+ L+ +     ++++k+RR+YDi+NVL+++nliek     ++k+++rw g
  XP_010913427.1 160 RREKSLGLLTQNFVKLFLTTDADTVSLDEAARLLLGDghdssQMRTKVRRLYDIANVLSSMNLIEKtqqleTRKPAFRWLG 240
                     689*******************************************************************99*******87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.6E-261686IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467853.27E-161984IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.4E-282085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.0E-202185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.104.8E-23157241IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.7E-32160240IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.39E-13162241IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.2E-20162240IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 398 aa     Download sequence    Send to blast
MASLPSPFLE SGCRHHTYSR KQKSLGLLCS NFVSLYDRDD VESVGLDDAA RRLGVERRRI  60
YDIVNVLESV GVLARKAKNR YSWIGFSGIP KALDELKEEA LKEISGTDGQ CVKVLEDEDE  120
GKLSDQNGNF GDYKPSPAAI GAASSLCTVA CKARSVTDNR REKSLGLLTQ NFVKLFLTTD  180
ADTVSLDEAA RLLLGDGHDS SQMRTKVRRL YDIANVLSSM NLIEKTQQLE TRKPAFRWLG  240
TKGKPKADTG VTVAIPPATK QWNKRAFGND ITNVDHKRSK LNNPVDKKPS KACLRSDDLK  300
ECNLTAQKQL QSSKGSYVFG PFRPAGVTKR NGDVEEKGGN KVQDWESLAS SFRPQYHNQA  360
LSELFVHYVE AWKSWYVEVA QGSSNFQQPR KSVINQLL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-40192323228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010913427.10.0E2F transcription factor-like E2FE isoform X4
SwissprotQ8LSZ41e-110E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2H3YFG20.0A0A2H3YFG2_PHODC; E2F transcription factor-like E2FE
STRINGXP_008798029.10.0(Phoenix dactylifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-107DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]