PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_011074654.1

Organism

Sesamum indicum

Taxonomic ID

4182

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

ARF

Protein Properties

Length: 1012aa MW: 112083 Da PI: 5.0717

Description

ARF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011074654.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	74.2	1.5e-23	146	247	1	99
EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 f+k+lt sd++++g +++p++ ae+ + ++++ ++l+++d++ ++W +++iyr++++r++lt+GW+ Fv a++L++gD v+F ++++ XP_011074654.1 146 FCKTLTASDTSTHGGFSVPRRAAEKLfpqldySTQPPT-QELVVRDLHDNTWAFRHIYRGQPKRHLLTTGWSMFVGAKRLRAGDAVLFI--RDEK 237 99*******************99998444444.49**********************************************..4567 PP E..EEEEE-S CS B3 90 felvvkvfrk 99 +l+++v+r XP_011074654.1 238 SQLMLGVRRV 247 7789999985 PP
2	Auxin_resp	119.4	2.8e-39	272	355	1	83
Auxin_resp 1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 aahaa+++s+F+++YnPra++seFv++++k++ka++ +++++GmRf m+fete+ss+rr++Gt++g+sd+dp+rWpnSkWrsL+ XP_011074654.1 272 AAHAAANRSPFTIFYNPRACPSEFVIPLAKYRKAVYgTQLAIGMRFGMMFETEESSKRRYMGTIIGISDVDPLRWPNSKWRSLQ 355 79********************************9*******************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101936	6.8E-47	133	275	IPR015300	DNA-binding pseudobarrel domain
Gene3D	G3DSA:2.40.330.10	1.3E-40	139	260	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	3.09E-21	145	246	No hit	No description
Pfam	PF02362	5.2E-21	146	247	IPR003340	B3 DNA binding domain
SMART	SM01019	2.1E-22	146	248	IPR003340	B3 DNA binding domain
PROSITE profile	PS50863	12.957	146	248	IPR003340	B3 DNA binding domain
Pfam	PF06507	4.3E-34	272	355	IPR010525	Auxin response factor
Pfam	PF02309	2.9E-8	893	980	IPR033389	AUX/IAA domain
PROSITE profile	PS51745	25.774	894	977	IPR000270	PB1 domain
SuperFamily	SSF54277	1.31E-8	913	972	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009725	Biological Process	response to hormone
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1012 aa Download sequence Send to blast
MGSVEEKLKP GGLISGAHNI LEGMKLLKEM QDHTGVKKQI NSELWHACAG PLVTLPQVGS 60 LVYYFPQGHS EQVAVSTNRT ATTQVPNYPN LPSQLLCQVH NVTLHADKET DEIYAQMSLQ 120 PVNSEKDIFP IPDFGLKHSK HPTEFFCKTL TASDTSTHGG FSVPRRAAEK LFPQLDYSTQ 180 PPTQELVVRD LHDNTWAFRH IYRGQPKRHL LTTGWSMFVG AKRLRAGDAV LFIRDEKSQL 240 MLGVRRVNRQ QTTLPSSVLS ADSMHIGILA AAAHAAANRS PFTIFYNPRA CPSEFVIPLA 300 KYRKAVYGTQ LAIGMRFGMM FETEESSKRR YMGTIIGISD VDPLRWPNSK WRSLQVEWDE 360 PGCIDKQNRV SPWEIETPES LFIFPSLAAT LKRPFHTAFV GAQPEWETML NRPFLRVPDN 420 SLGDLQCPPI SSLWSEQLMK MLTKPPGLIA PGSIAYSMQE VKDVVPREAT SVMQPAMKQR 480 PELILQDVYP QGESNLQSVA GQPIITNPHI LAGSDLSKQE PVLTTDQLIQ FQSESQLNEE 540 RMPVKPLNPH NLINDFAVTN QHNGTVSLQT SSCITQSRLD SHALPAGKLT SAEAGSELSK 600 QEPVLATDQL SQFESEMQLN EKSMPVRPVN PQNVINDFAV TNQNNGMPAL HTSPYISHSR 660 LDPHILQTQQ IDPSQVTSAS ANDLPQYSSQ VEFNSYSSIY PPPSGSLRNP RPPSMLQKSD 720 QLSTSSDIVY PMLPSVEQEL WDPHYNDAKC VSQTNLPVLL PHQDMSNLQY SSCGLKDVSD 780 EENNQSDLYS CVNLDGSNSG STVIDPSVSS TILDDFCTLK NVDFSNPSDY FVGNFCSTQD 840 VQSQITSASL ADSQNFSLQE YADNSGGASS SNIDYDDNNL LQQSSFQQVT PRFRTYTKIQ 900 KAGSVGRSID VSGFRNYKEL LSEIECMFGL TGLLNDSGSG WKLVYVDFEN DVLLVGDDPW 960 EEFVGCVRCI RILSPSEVKQ MGEEGMQLLN SVGMQGVNGS TLEVGCAKDG SN

Sequence ? help Back to Top

Protein Sequence Length: 1012 aa Download sequence Send to blast

MGSVEEKLKP GGLISGAHNI LEGMKLLKEM QDHTGVKKQI NSELWHACAG PLVTLPQVGS  60
LVYYFPQGHS EQVAVSTNRT ATTQVPNYPN LPSQLLCQVH NVTLHADKET DEIYAQMSLQ  120
PVNSEKDIFP IPDFGLKHSK HPTEFFCKTL TASDTSTHGG FSVPRRAAEK LFPQLDYSTQ  180
PPTQELVVRD LHDNTWAFRH IYRGQPKRHL LTTGWSMFVG AKRLRAGDAV LFIRDEKSQL  240
MLGVRRVNRQ QTTLPSSVLS ADSMHIGILA AAAHAAANRS PFTIFYNPRA CPSEFVIPLA  300
KYRKAVYGTQ LAIGMRFGMM FETEESSKRR YMGTIIGISD VDPLRWPNSK WRSLQVEWDE  360
PGCIDKQNRV SPWEIETPES LFIFPSLAAT LKRPFHTAFV GAQPEWETML NRPFLRVPDN  420
SLGDLQCPPI SSLWSEQLMK MLTKPPGLIA PGSIAYSMQE VKDVVPREAT SVMQPAMKQR  480
PELILQDVYP QGESNLQSVA GQPIITNPHI LAGSDLSKQE PVLTTDQLIQ FQSESQLNEE  540
RMPVKPLNPH NLINDFAVTN QHNGTVSLQT SSCITQSRLD SHALPAGKLT SAEAGSELSK  600
QEPVLATDQL SQFESEMQLN EKSMPVRPVN PQNVINDFAV TNQNNGMPAL HTSPYISHSR  660
LDPHILQTQQ IDPSQVTSAS ANDLPQYSSQ VEFNSYSSIY PPPSGSLRNP RPPSMLQKSD  720
QLSTSSDIVY PMLPSVEQEL WDPHYNDAKC VSQTNLPVLL PHQDMSNLQY SSCGLKDVSD  780
EENNQSDLYS CVNLDGSNSG STVIDPSVSS TILDDFCTLK NVDFSNPSDY FVGNFCSTQD  840
VQSQITSASL ADSQNFSLQE YADNSGGASS SNIDYDDNNL LQQSSFQQVT PRFRTYTKIQ  900
KAGSVGRSID VSGFRNYKEL LSEIECMFGL TGLLNDSGSG WKLVYVDFEN DVLLVGDDPW  960
EEFVGCVRCI RILSPSEVKQ MGEEGMQLLN SVGMQGVNGS TLEVGCAKDG SN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldu_A	0.0	1	380	5	392	Auxin response factor 5
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. {ECO:0000269\|PubMed:12036261, ECO:0000269\|PubMed:14973283, ECO:0000269\|PubMed:17553903}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011074654.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011074654.1	0.0	auxin response factor 5
Refseq	XP_011074656.1	0.0	auxin response factor 5
Refseq	XP_011074657.1	0.0	auxin response factor 5
Swissprot	P93024	0.0	ARFE_ARATH; Auxin response factor 5
TrEMBL	A0A191T8S8	0.0	A0A191T8S8_SALMI; Auxin response factor
STRING	XP_009778804.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5859	23	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19850.1	0.0	ARF family protein

Publications ? help Back to Top
Chen MK,Wilson RL,Palme K,Ditengou FA,Shpak ED ERECTA family genes regulate auxin transport in the shoot apical meristem and forming leaf primordia. Plant Physiol., 2013. 162(4): p. 1978-91 [PMID:23821653] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Qi J, et al. Auxin depletion from leaf primordia contributes to organ patterning. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(52): p. 18769-74 [PMID:25512543] Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Zhang Y, et al. Regulation of oncogene expression in T-DNA-transformed host plant cells. PLoS Pathog., 2015. 11(1): p. e1004620 [PMID:25615824] Robert HS, et al. Plant embryogenesis requires AUX/LAX-mediated auxin influx. Development, 2015. 142(4): p. 702-11 [PMID:25617434] Krogan NT,Berleth T The identification and characterization of specific ARF-Aux/IAA regulatory modules in plant growth and development. Plant Signal Behav, 2015. 10(4): p. e992748 [PMID:25830553] Ckurshumova W,Berleth T Overcoming recalcitrance - Auxin response factor functions in plant regeneration. Plant Signal Behav, 2015. 10(7): p. e993293 [PMID:26098229] Wendrich JR, et al. A set of domain-specific markers in the Arabidopsis embryo. Plant Reprod, 2015. 28(3-4): p. 153-60 [PMID:26216537] Wu MF, et al. Auxin-regulated chromatin switch directs acquisition of flower primordium founder fate. Elife, 2015. 4: p. e09269 [PMID:26460543] Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis. Plant Physiol., 2016. 170(1): p. 283-93 [PMID:26537561] Müller CJ, et al. PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis. Plant Physiol., 2016. 170(2): p. 956-70 [PMID:26637548] Herud O,Weijers D,Lau S,Jürgens G Auxin responsiveness of the MONOPTEROS-BODENLOS module in primary root initiation critically depends on the nuclear import kinetics of the Aux/IAA inhibitor BODENLOS. Plant J., 2016. 85(2): p. 269-77 [PMID:26714008] Luo S, et al. Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis. Front Plant Sci, 2015. 6: p. 1156 [PMID:26734051] Yamaguchi N,Wu MF,Winter CM,Wagner D LEAFY and Polar Auxin Transport Coordinately Regulate Arabidopsis Flower Development. Plants (Basel), 2014. 3(2): p. 251-65 [PMID:27135503] Krogan NT,Marcos D,Weiner AI,Berleth T The auxin response factor MONOPTEROS controls meristem function and organogenesis in both the shoot and root through the direct regulation of PIN genes. New Phytol., 2016. 212(1): p. 42-50 [PMID:27441727] Fendrych M,Leung J,Friml J TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls. Elife, 2018. [PMID:27627746] Matthes M,Torres-Ruiz RA Boronic acid treatment phenocopies monopteros by affecting PIN1 membrane stability and polar auxin transport in Arabidopsis thaliana embryos. Development, 2016. 143(21): p. 4053-4062 [PMID:27697905] Bhatia N, et al. Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis. Curr. Biol., 2016. 26(23): p. 3202-3208 [PMID:27818174] Wójcikowska B,Gaj MD Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis. Plant Cell Rep., 2017. 36(6): p. 843-858 [PMID:28255787] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Carey NS,Krogan NT The role of AUXIN RESPONSE FACTORs in the development and differential growth of inflorescence stems. Plant Signal Behav, 2017. 12(4): p. e1307492 [PMID:28340328] Guan C, et al. Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis. Curr. Biol., 2017. 27(19): p. 2940-2950.e4 [PMID:28943086] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667] Zheng K, et al. Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis. Front Plant Sci, 2017. 8: p. 1813 [PMID:29114256] Liu Z, et al. ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis. Plant Cell Physiol., 2018. 59(1): p. 179-189 [PMID:29145642]