PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_013894873.1
Organism
Monoraphidium neglectum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae; Sphaeropleales; Selenastraceae; Monoraphidium
Family E2F/DP
Protein Properties Length: 199aa    MW: 22294.4 Da    PI: 4.7357
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_013894873.1genomeBUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.21.2e-2746110170
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwk 70 
                     r ++sL++lt+kfl+l+ek+e+gi++ln++a+eL   +v  ++RRiYDi+NVLe+++liekk+kn+i wk
  XP_013894873.1  46 RFDSSLGMLTKKFLNLIEKAEDGILDLNQAAEEL---QV--QKRRIYDITNVLEGVGLIEKKSKNNILWK 110
                     6789******************************...99..****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.2E-2744110IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.29E-1846109IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.3E-3346111IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.0E-2548110IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.1E-9131189No hitNo description
PfamPF164212.7E-6134190IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 199 aa     Download sequence    Send to blast
MREDHEDDQD WQSPTRLGKR KTSRRMARSP DEKPSRETAN YGTGCRFDSS LGMLTKKFLN  60
LIEKAEDGIL DLNQAAEELQ VQKRRIYDIT NVLEGVGLIE KKSKNNILWK PMVMEPAVLP  120
GPDADAQQEM LDALNQQTAM LRDQEGALDA QIASVMDALR GMTEHPANKP YLFVTDEDIT  180
GLPCFAHGLT MSLIGLNCC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-2542110372PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013894873.11e-148hypothetical protein MNEG_12111
SwissprotQ9FV712e-39E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A0D2KJ481e-147A0A0D2KJ48_9CHLO; Uncharacterized protein
STRINGEDP095265e-47(Chlamydomonas reinhardtii)
STRINGEFX604963e-49(Daphnia pulex)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
ChlorophytaeOGCP32581314
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.37e-42E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Bogen C, et al.
    Reconstruction of the lipid metabolism for the microalga Monoraphidium neglectum from its genome sequence reveals characteristics suitable for biofuel production.
    BMC Genomics, 2013. 14: p. 926
    [PMID:24373495]
  4. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]