PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_015868935.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus
Family HSF
Protein Properties Length: 217aa    MW: 23803.2 Da    PI: 8.2424
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_015868935.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind75.59.7e-241877261
                    HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTT CS
    HSF_DNA-bind  2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYg 61
                    Fl k+y++++d++++e++sws+ ++sfvv+++ efa+ +Lp++Fkh+nf+SF+RQLn+Y 
  XP_015868935.1 18 FLLKTYDMVDDSSTDEIVSWSSVKTSFVVWNPPEFARLLLPTFFKHNNFSSFIRQLNTYT 77
                    9**********************************************************5 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.7E-251177IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467855.03E-221478IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004154.9E-271497IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.3E-131841IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004474.2E-201877IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.3E-135668IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.3E-136981IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF533835.72E-3578208IPR015424Pyridoxal phosphate-dependent transferase
PfamPF004641.5E-2779157IPR001085Serine hydroxymethyltransferase
Gene3DG3DSA:3.90.1150.101.7E-5180209IPR015422Pyridoxal phosphate-dependent transferase, major region, subdomain 2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0016740Molecular Functiontransferase activity
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 217 aa     Download sequence    Send to blast
MDGAQAAGSG SSGGPAPFLL KTYDMVDDSS TDEIVSWSSV KTSFVVWNPP EFARLLLPTF  60
FKHNNFSSFI RQLNTYTSPH KLVTGGTENH LVLWDLRPLG LTGNKVEKLC DLCNITVNKN  120
AVFGDSSALA PGGVRIGTPA MTSRGLLEKD FEQIGEFLHR AVTITLSIQK EHGKLLKDFN  180
KGLGKNKDIE ALKADVEKFS SSFHMPGFQM SAMKYKD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1bj4_A1e-3680208337470PROTEIN (SERINE HYDROXYMETHYLTRANSFERASE)
6fl5_A1e-3680208337470Serine hydroxymethyltransferase, cytosolic
6fl5_D1e-3680208337470Serine hydroxymethyltransferase, cytosolic
6fl5_G1e-3680208337470Serine hydroxymethyltransferase, cytosolic
6fl5_J1e-3680208337470Serine hydroxymethyltransferase, cytosolic
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtCatalyzes the interconversion of serine and glycine. {ECO:0000250}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_015868935.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation. {ECO:0000269|PubMed:10806255}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015868935.11e-161serine hydroxymethyltransferase 4-like
SwissprotO232542e-77GLYC4_ARATH; Serine hydroxymethyltransferase 4
TrEMBLA0A067DKJ34e-86A0A067DKJ3_CITSI; Uncharacterized protein (Fragment)
TrEMBLA0A161Y5N41e-85A0A161Y5N4_DAUCS; Serine hydroxymethyltransferase
STRINGevm.model.supercontig_157.476e-85(Carica papaya)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G13980.12e-28HSF family protein
Publications ? help Back to Top
  1. McClung CR, et al.
    Integrated temporal regulation of the photorespiratory pathway. Circadian regulation of two Arabidopsis genes encoding serine hydroxymethyltransferase.
    Plant Physiol., 2000. 123(1): p. 381-92
    [PMID:10806255]
  2. Bauwe H,Kolukisaoglu U
    Genetic manipulation of glycine decarboxylation.
    J. Exp. Bot., 2003. 54(387): p. 1523-35
    [PMID:12730263]
  3. Wienkoop S, et al.
    Cell-specific protein profiling in Arabidopsis thaliana trichomes: identification of trichome-located proteins involved in sulfur metabolism and detoxification.
    Phytochemistry, 2004. 65(11): p. 1641-9
    [PMID:15276459]
  4. Nikiforova VJ,Daub CO,Hesse H,Willmitzer L,Hoefgen R
    Integrative gene-metabolite network with implemented causality deciphers informational fluxes of sulphur stress response.
    J. Exp. Bot., 2005. 56(417): p. 1887-96
    [PMID:15911562]
  5. Noir S,Bräutigam A,Colby T,Schmidt J,Panstruga R
    A reference map of the Arabidopsis thaliana mature pollen proteome.
    Biochem. Biophys. Res. Commun., 2005. 337(4): p. 1257-66
    [PMID:16242667]
  6. Holmes-Davis R,Tanaka CK,Vensel WH,Hurkman WJ,McCormick S
    Proteome mapping of mature pollen of Arabidopsis thaliana.
    Proteomics, 2005. 5(18): p. 4864-84
    [PMID:16247729]
  7. Sivanandan C, et al.
    T-DNA tagging and characterization of a cryptic root-specific promoter in Arabidopsis.
    Biochim. Biophys. Acta, 2005. 1731(3): p. 202-8
    [PMID:16307804]
  8. Rajjou L, et al.
    Proteomic investigation of the effect of salicylic acid on Arabidopsis seed germination and establishment of early defense mechanisms.
    Plant Physiol., 2006. 141(3): p. 910-23
    [PMID:16679420]
  9. Mull L,Ebbs ML,Bender J
    A histone methylation-dependent DNA methylation pathway is uniquely impaired by deficiency in Arabidopsis S-adenosylhomocysteine hydrolase.
    Genetics, 2006. 174(3): p. 1161-71
    [PMID:16951055]
  10. Ichikawa T, et al.
    The FOX hunting system: an alternative gain-of-function gene hunting technique.
    Plant J., 2006. 48(6): p. 974-85
    [PMID:17227551]
  11. Marmagne A, et al.
    A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.
    Mol. Cell Proteomics, 2007. 6(11): p. 1980-96
    [PMID:17644812]
  12. Hajduch M, et al.
    Systems analysis of seed filling in Arabidopsis: using general linear modeling to assess concordance of transcript and protein expression.
    Plant Physiol., 2010. 152(4): p. 2078-87
    [PMID:20118269]
  13. Zhang Y,Sun K,Sandoval FJ,Santiago K,Roje S
    One-carbon metabolism in plants: characterization of a plastid serine hydroxymethyltransferase.
    Biochem. J., 2010. 430(1): p. 97-105
    [PMID:20518745]
  14. Lozano-Juste J,Colom-Moreno R,León J
    In vivo protein tyrosine nitration in Arabidopsis thaliana.
    J. Exp. Bot., 2011. 62(10): p. 3501-17
    [PMID:21378116]
  15. Zhou H, et al.
    Ubiquitin-specific protease16 modulates salt tolerance in Arabidopsis by regulating Na(+)/H(+) antiport activity and serine hydroxymethyltransferase stability.
    Plant Cell, 2012. 24(12): p. 5106-22
    [PMID:23232097]
  16. Schenck CA, et al.
    A proteomics approach identifies novel proteins involved in gravitropic signal transduction.
    Am. J. Bot., 2013. 100(1): p. 194-202
    [PMID:23281391]
  17. Wei Z, et al.
    Folate polyglutamylation eliminates dependence of activity on enzyme concentration in mitochondrial serine hydroxymethyltransferases from Arabidopsis thaliana.
    Arch. Biochem. Biophys., 2013. 536(1): p. 87-96
    [PMID:23800877]