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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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| Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
| Basic Information? help Back to Top | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| TF ID | XP_015898821.1 | ||||||||
| Organism | |||||||||
| Taxonomic ID | |||||||||
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus
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| Family | E2F/DP | ||||||||
| Protein Properties | Length: 472aa MW: 52156.1 Da PI: 4.8256 | ||||||||
| Description | E2F/DP family protein | ||||||||
| Gene Model |
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| Signature Domain? help Back to Top | |||||||
|---|---|---|---|---|---|---|---|
| No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
| 1 | E2F_TDP | 86.1 | 2.5e-27 | 147 | 212 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg
XP_015898821.1 147 RYDSSLGLLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 212
6899******************************...99..****************************98 PP
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| Protein Features ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Database | Entry ID | E-value | Start | End | InterPro ID | Description |
| Gene3D | G3DSA:1.10.10.10 | 3.1E-29 | 144 | 214 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
| SuperFamily | SSF46785 | 5.08E-17 | 147 | 210 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
| SMART | SM01372 | 2.0E-34 | 147 | 212 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
| Pfam | PF02319 | 2.4E-24 | 149 | 212 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
| SuperFamily | SSF144074 | 1.73E-33 | 225 | 329 | No hit | No description |
| Pfam | PF16421 | 1.4E-32 | 228 | 327 | IPR032198 | E2F transcription factor, CC-MB domain |
| CDD | cd14660 | 3.43E-47 | 228 | 329 | No hit | No description |
| Gene Ontology ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| GO Term | GO Category | GO Description | ||||
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
| GO:0005667 | Cellular Component | transcription factor complex | ||||
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
| Sequence ? help Back to Top |
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| Protein Sequence Length: 472 aa Download sequence Send to blast |
MSGNPRAPNR PTPPPPVPSG GGQILPPLRR HLAFASTKPP FLPPDDYHRF SGDAHRAADQ 60 EPEAIVVRSP QLKRKNGIDN SEVEHGDWMS GSGYTNVINS PLNTPVSAKG GRAYNRSKTS 120 KGNRSAPQTP VSNAGSPSPL TPAGSCRYDS SLGLLTKKFI NLIKHAEDGI LDLNKAAETL 180 EVQKRRIYDI TNVLEGIGLI EKKLKNRIRW KGLDASRPGE VDGDITTLQA EVDNLSMEER 240 RLDDRIREMQ ERLRDLSEDE NNQKWLFVTE DDIKGLPCFQ NETLIAIKAP HGTTLEVPDP 300 DEAVDYPQRR YRIILRSTMG PVDVYLVSQF EEKFEEMNGV VPPASFPLAS SSGSNEHPVT 360 EVVTMDNTRK DIEPQVQNDH QMCSDINASQ EFGGGMMKIV PSDVDNDADY WLLSDAEVSI 420 TDMWRTDSGV DWNGADILHA DFGMTDVSTP RSQDPPSGIA EAPTSNVHFS PR |
| 3D Structure ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
| 1cf7_A | 2e-23 | 142 | 213 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
| Search in ModeBase | ||||||
| Functional Description ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Description | |||||
| UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. | |||||
| Binding Motif ? help Back to Top | |||
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| Motif ID | Method | Source | Motif file |
| MP00661 | PBM | Transfer from Pp3c1_6880 | Download |
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| Cis-element ? help Back to Top | |
|---|---|
| Source | Link |
| PlantRegMap | XP_015898821.1 |
| Regulation -- PlantRegMap ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Source | Upstream Regulator | Target Gene | ||||
| PlantRegMap | Retrieve | Retrieve | ||||
| Annotation -- Protein ? help Back to Top | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-value | Description | ||||
| Refseq | XP_015898821.1 | 0.0 | transcription factor E2FA isoform X1 | ||||
| Swissprot | Q9FNY0 | 0.0 | E2FA_ARATH; Transcription factor E2FA | ||||
| TrEMBL | A0A2P5D9W8 | 0.0 | A0A2P5D9W8_PARAD; E2F Family | ||||
| STRING | EMJ05533 | 0.0 | (Prunus persica) | ||||
| Orthologous Group ? help Back to Top | |||
|---|---|---|---|
| Lineage | Orthologous Group ID | Taxa Number | Gene Number |
| Fabids | OGEF1947 | 34 | 90 |
| Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
|---|---|---|---|---|---|---|
| Hit ID | E-value | Description | ||||
| AT2G36010.1 | 0.0 | E2F transcription factor 3 | ||||
| Publications ? help Back to Top | |||
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