PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_015902932.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus
Family E2F/DP
Protein Properties Length: 208aa    MW: 23831.4 Da    PI: 6.3631
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_015902932.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP46.27.6e-1541694270
         E2F_TDP 42 krRRiYDilNVLealnliekkekneirwk 70
                     +RRiYDi+NVLe+++liek++k++irwk
  XP_015902932.1 41 LKRRIYDITNVLEGIRLIEKTSKSHIRWK 69
                    69**************************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013725.2E-6870IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.9E-133269IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.16E-93469IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.8E-124069IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146609.67E-3285187No hitNo description
SuperFamilySSF1440743.92E-2585187No hitNo description
PfamPF164212.3E-2288186IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 208 aa     Download sequence    Send to blast
MILSSFIHKA HNFPSNTQIP QKAQTKPRSK PNTETGLIVV LKRRIYDITN VLEGIRLIEK  60
TSKSHIRWKR SEASGLQRVD DRGAIQELQA EVEGLYAEEY RMDETIKEKQ DLIRALAEDE  120
NFKKKLYLTA EDILTLPCFQ DETVIAIKAP RTSYIEVPGP DQDNESSGEY KMIVRSHMGP  180
IDLYLLSCVF CFSCMDIHME IPLVRTTG
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_015902932.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015902932.11e-155transcription factor E2FC-like
SwissprotQ9FV706e-47E2FC_ARATH; Transcription factor E2FC
TrEMBLW9SD412e-57W9SD41_9ROSA; Transcription factor E2FC
STRINGXP_010104441.13e-58(Morus notabilis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.22e-49E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]