PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016432452.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 494aa    MW: 57088.5 Da    PI: 7.8501
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016432452.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2187.8e-06187207323
                     ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   3 CpdCgksFsrksnLkrHirtH 23 
                     C+ Cg sF  + +Lk+H+++H
  XP_016432452.1 187 CEECGVSFQKPAHLKQHMQSH 207
                     *******************99 PP
2zf-C2H217.51.2e-05213237123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     ++C+  dC  s++rk++L+rH+  H
  XP_016432452.1 213 FVCHidDCQSSYRRKDHLTRHLLQH 237
                     89*******************9887 PP
3zf-C2H215.54.9e-05242267123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     ++Cp   C++sFs + n++rH +  H
  XP_016432452.1 242 FECPvdGCKRSFSIQGNMTRHVKEmH 267
                     89********************9988 PP
4zf-C2H218.84.5e-06281305123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C+   Cgk+F+  s Lk+H  +H
  XP_016432452.1 281 YVCSepGCGKVFKFASKLKKHEDSH 305
                     89*******************9888 PP
5zf-C2H218.65.1e-06372396223
                     EET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                     kC+  dC  +Fs+ksnL +H +  H
  XP_016432452.1 372 KCEfqDCQHTFSTKSNLIKHVKAvH 396
                     79999***************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF003855.8E-6940IPR023780Chromo domain
SMARTSM0035548138161IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.75E-9184237No hitNo description
SMARTSM003550.0095185207IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.884185212IPR007087Zinc finger, C2H2
PROSITE patternPS000280187207IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.7E-7187211IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
Gene3DG3DSA:3.30.160.608.7E-9212239IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.411213242IPR007087Zinc finger, C2H2
SMARTSM003550.027213237IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280215237IPR007087Zinc finger, C2H2
SuperFamilySSF576673.44E-6223267No hitNo description
Gene3DG3DSA:3.30.160.604.5E-5240267IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.91242267IPR007087Zinc finger, C2H2
SMARTSM003556.5E-4242267IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280244267IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.5E-8276305IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.79E-5279307No hitNo description
SMARTSM003550.0038281305IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.136281310IPR007087Zinc finger, C2H2
PROSITE patternPS000280283305IPR007087Zinc finger, C2H2
SMARTSM003558.8313338IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280315338IPR007087Zinc finger, C2H2
SMARTSM0035513341362IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.24E-10353409No hitNo description
PROSITE profilePS5015713.609371401IPR007087Zinc finger, C2H2
SMARTSM003559.3E-4371396IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.0E-6372398IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280373396IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.0E-4399424IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003559.8402428IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280404428IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 494 aa     Download sequence    Send to blast
MVKVNNGVSV KVLVQWANLK AEDATWEDWG YLKSKFPEFV EVTNIIHLQD QKLSIKKGDY  60
ATSKRTGEEF VVVTVSFNKT FAGATVIYCD EVAVMERVSS EEVLPKDFPL GFWCFVAVQI  120
LGEMGEEREV IFRDIRRYYC EFCGICRSKQ SLISSHILSY HQDEMEKRKD EANEDAKIKK  180
CPKLNICEEC GVSFQKPAHL KQHMQSHSLE RLFVCHIDDC QSSYRRKDHL TRHLLQHQGK  240
LFECPVDGCK RSFSIQGNMT RHVKEMHDHC ASPEANLPKH YVCSEPGCGK VFKFASKLKK  300
HEDSHVKLET MEALCLEPGC MKHFTNEKCL KEHIESCHQH IVCEICGTKQ LKKNIKRHLR  360
THEEESTSER IKCEFQDCQH TFSTKSNLIK HVKAVHLGDK PFSCSIVGCD MKFAFKHVRD  420
RHEKSGCHVY TPGDFIEADE QFRSRPRGGR KRKLPVFEAI MRKRITPPCG TDPVFYQGSE  480
YLSWLLSAES DEEL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A3e-1518933319155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D3e-1518933319155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1444452RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKX0986000.0KX098600.1 Nicotiana benthamiana transcription factor IIIA 9ZF mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016432452.10.0PREDICTED: transcription factor IIIA-like
SwissprotQ84MZ41e-124TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1S3WXV90.0A0A1S3WXV9_TOBAC; transcription factor IIIA-like
STRINGXP_009761650.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA36442447
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-126transcription factor IIIA