PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016434433.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 607aa    MW: 67390.9 Da    PI: 6.8441
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016434433.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.86.9e-12438484455
                     HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                     +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ +I +Lq
  XP_016434433.1 438 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAHITELQ 484
                     799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142158.9E-5652240IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.475434483IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474594.84E-18437499IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.69E-13437488No hitNo description
Gene3DG3DSA:4.10.280.102.2E-17438498IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.2E-9438484IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.6E-16440489IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 607 aa     Download sequence    Send to blast
MKIEMGLGKM LWGDEDKAMV AAVLGTKAFD YLMSSSVSAE CSLMAMGNDE NLQNKLSDLV  60
ERPNGANFSW NYAIFWQISR SKSGELVLGW GDGCCREPRE GEGSEVSRIL NLRLENEAQQ  120
RMRKRVLEKL HMLFGGTDED NYAFGLDKVT DTEMFFLASM YFSFPRGEGG PGKCFGSGKH  180
VWLSDVMKSS VDYCSRSFLM KSAGMQTIVL IPTDVGVVEL GSVRAISESL ELVQSIESCF  240
SSFLSLVRAK QAGSVTVVAE KKDGNGSPYS SSFVSEQPNG IPKIFGQNLN SGCTPFREKL  300
AVRKAEDRAL EMYQNGNRAQ FMNARNGLRA ASWASFSNVK PVNSMDPYRP QIPANNIRDF  360
VNGTREEFHI NNFQHQKSAS MQIDFTNSRP VISPAQTVES EHSDVEASCK EDHTGPADDK  420
RPRKRGRKPA NGREEPLNHV EAERQRREKL NQRFYALRAV VPNISKMDKA SLLGDAIAHI  480
TELQKKLRDM ESERERLGST SRDANASASD CPNSETQNRV PDINIEAAND EVVVRVRCAL  540
ETHPVSRVIE AFKEARVNVV ESKLAAGNDT VYHTFVVESS GSEQLTKEKL MAAFSGESNA  600
LRPSPVR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-28432494264Transcription factor MYC2
5gnj_B3e-28432494264Transcription factor MYC2
5gnj_E3e-28432494264Transcription factor MYC2
5gnj_F3e-28432494264Transcription factor MYC2
5gnj_G3e-28432494264Transcription factor MYC2
5gnj_I3e-28432494264Transcription factor MYC2
5gnj_M3e-28432494264Transcription factor MYC2
5gnj_N3e-28432494264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1419427KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009770264.10.0PREDICTED: transcription factor bHLH13-like
RefseqXP_016434433.10.0PREDICTED: transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1S3X4040.0A0A1S3X404_TOBAC; transcription factor bHLH13-like
TrEMBLA0A1U7W6I50.0A0A1U7W6I5_NICSY; transcription factor bHLH13-like
STRINGXP_009770264.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]