PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016435385.1

Common Name

ZFT1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 253aa MW: 27033.1 Da PI: 7.8259

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016435385.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	10.9	0.0014	93	115	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC+ Cgk F + L H +H XP_016435385.1 93 YKCSVCGKGFGSYQALGGHKASH 115 9*********9999998888777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13912	3.0E-13	92	117	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.48E-9	92	115	No hit	No description
Gene3D	G3DSA:3.30.160.60	9.5E-4	93	115	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.019	93	115	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.325	93	115	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	95	115	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.48E-9	150	177	No hit	No description
Pfam	PF13912	3.0E-11	154	179	IPR007087	Zinc finger, C2H2
SMART	SM00355	1.8	155	177	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.058	155	177	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	157	177	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 253 aa Download sequence Send to blast
MALETLNSPT TTTPPTFQFE NNGQLRYLEN WTKGKRSKRP RSMERQPTEE EYLALCLIML 60 ARSDGSANQE QSLTPPPAPV MKIHAPPEEK MVYKCSVCGK GFGSYQALGG HKASHRKLVA 120 GGGGGDDQST TSTTTNATGT TSSANGNGNG SGKTHECSIC HKCFPTGQAL GGHKRCHYDG 180 GNSNASVSVS ASVGVTSSEG VGSTVSHRDF DLNIPALPEF WPRFGFGEDE VESPHPAKKS 240 RLSLPPKFEL FGE

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. {ECO:0000269\|PubMed:12032082, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:17112521, ECO:0000269\|PubMed:18216250, ECO:0000269\|PubMed:20140232, ECO:0000269\|PubMed:8662738}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salt, cold and drought stresses. Down-regulated by gibberellin. {ECO:0000269\|PubMed:10806347, ECO:0000269\|PubMed:11351099, ECO:0000269\|PubMed:12837949, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:17112521, ECO:0000269\|PubMed:8662738}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB186899	0.0	AB186899.1 Nicotiana tabacum ZFT1 mRNA for Cys2-His2 type zinc finger protein, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001311653.1	0.0	zinc finger protein ZAT10-like
Refseq	XP_009771319.1	0.0	PREDICTED: zinc finger protein ZAT10-like
Swissprot	Q96289	1e-66	ZAT10_ARATH; Zinc finger protein ZAT10
TrEMBL	A0A1U7W9J1	0.0	A0A1U7W9J1_NICSY; zinc finger protein ZAT10-like
TrEMBL	Q4AEC3	0.0	Q4AEC3_TOBAC; Cys2-His2 type zinc finger protein
STRING	XP_009771319.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA735	24	95

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G27730.1	2e-51	salt tolerance zinc finger

Publications ? help Back to Top
Uehara Y, et al. Tobacco ZFT1, a transcriptional repressor with a Cys2/His2 type zinc finger motif that functions in spermine-signaling pathway. Plant Mol. Biol., 2005. 59(3): p. 435-48 [PMID:16235109] Li C,Chang PP,Ghebremariam KM,Qin L,Liang Y Overexpression of tomato SpMPK3 gene in Arabidopsis enhances the osmotic tolerance. Biochem. Biophys. Res. Commun., 2014. 443(2): p. 357-62 [PMID:24275141] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Shi H,Chan Z The cysteine2/histidine2-type transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activated C-REPEAT-BINDING FACTOR pathway is essential for melatonin-mediated freezing stress resistance in Arabidopsis. J. Pineal Res., 2014. 57(2): p. 185-91 [PMID:24962049] Munekage YN,Inoue S,Yoneda Y,Yokota A Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana. Plant Cell Environ., 2015. 38(6): p. 1116-26 [PMID:25293694] van Buer J,Cvetkovic J,Baier M Cold regulation of plastid ascorbate peroxidases serves as a priming hub controlling ROS signaling in Arabidopsis thaliana. BMC Plant Biol., 2016. 16(1): p. 163 [PMID:27439459] Corrales AR, et al. Multifaceted role of cycling DOF factor 3 (CDF3) in the regulation of flowering time and abiotic stress responses in Arabidopsis. Plant Cell Environ., 2017. 40(5): p. 748-764 [PMID:28044345] Nguyen HM, et al. Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice. Front Plant Sci, 2017. 8: p. 1001 [PMID:28717360] Geilen K,Heilmann M,Hillmer S,Böhmer M WRKY43 regulates polyunsaturated fatty acid content and seed germination under unfavourable growth conditions. Sci Rep, 2017. 7(1): p. 14235 [PMID:29079824] Liu X, et al. Histone Deacetylase AtSRT1 Links Metabolic Flux and Stress Response in Arabidopsis. Mol Plant, 2017. 10(12): p. 1510-1522 [PMID:29107034] Huang K, et al. Arabidopsis calcium-dependent protein kinase AtCPK1 plays a positive role in salt/drought-stress response. Biochem. Biophys. Res. Commun., 2018. 498(1): p. 92-98 [PMID:29196259]