PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016436245.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family TALE
Protein Properties Length: 513aa    MW: 57833.6 Da    PI: 7.3519
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016436245.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.92e-093273592254
                     SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS
        Homeobox  22 nrypsaeereeLAkklgLterqVkvWFqNrRak 54 
                     ++yp+ +++  LAk++gL+ +qV++WF N R +
  XP_016436245.1 327 HPYPTDTDKVMLAKQTGLSRNQVSNWFINARVR 359
                     89*****************************88 PP
2BELL104.11e-33187256372
            BELL   3 qelqkkkakLlslleeVdkrYkqyveqlqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeqi 72 
                      e+ kkk++L+ +l+eV++rYkqy++qlq+v+ sFe vaglg+a+p+++lAlk++S+hF cLk+ai++q+
  XP_016436245.1 187 DEHGKKKSRLILMLHEVYQRYKQYHQQLQMVVTSFESVAGLGNAAPFANLALKTMSKHFNCLKNAITDQL 256
                     5899***************************************************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005745.8E-42126254IPR006563POX domain
PfamPF075269.1E-34131253IPR006563POX domain
PROSITE profilePS5007111.872300363IPR001356Homeobox domain
SMARTSM003898.6E-10303367IPR001356Homeobox domain
CDDcd000861.03E-11303364No hitNo description
SuperFamilySSF466894.28E-17305369IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.6E-27306367IPR009057Homeodomain-like
PfamPF059201.1E-18320359IPR008422Homeobox KN domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 513 aa     Download sequence    Send to blast
MAEGFEPYHV PQQSRRDKLR VLVDDNLQLQ NYPSCLVPLY DPSIISSDLP SFQEINGTPF  60
FYTPQNLRFL DQSIRTSGED MVHNNNNNNN NTNGQGLSLS LSSLHHNTTN HDFLSKSSCV  120
PLGPFTGYSL ILKRSRFLKP AQLLLEELSC DVGREIYAEK LAADDFNLMD PSHENIVVDR  180
QDCSNGDEHG KKKSRLILML HEVYQRYKQY HQQLQMVVTS FESVAGLGNA APFANLALKT  240
MSKHFNCLKN AITDQLQFTN ESRHGQRNCE RDPIPRVGKG LYCQRPDQIH NNAGFADRTQ  300
PIWRPQRGLP ERAVTVLRAW LFDHFLHPYP TDTDKVMLAK QTGLSRNQVS NWFINARVRL  360
WKPMVEEIHM LETKEAHNKA SQREGHNSNN NNNSIEHFPT SNSHAACETP STSAPRLQDT  420
PPKRTRNDFP MGNADSISLS YGNLSTGTSG VSLTLGLHQN TGIGLSEPFP INAARRFGID  480
ANSDRFIVGG FEEQNGQFGR NFVGGQFLHD FAG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3k2a_A3e-15309367563Homeobox protein Meis2
3k2a_B3e-15309367563Homeobox protein Meis2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patterning by negatively regulating SHP expression in order to prevent replum cells from adopting a valve margin cell fate. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989, ECO:0000269|PubMed:15120075, ECO:0000269|PubMed:15155890, ECO:0000269|PubMed:16741748}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016436245.10.0PREDICTED: BEL1-like homeodomain protein 9
SwissprotQ9LZM81e-110BLH9_ARATH; BEL1-like homeodomain protein 9
TrEMBLA0A1S3X8A10.0A0A1S3X8A1_TOBAC; BEL1-like homeodomain protein 9
STRINGXP_009606015.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35202237
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02030.11e-111TALE family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  3. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]
  4. Andrés F, et al.
    Floral Induction in Arabidopsis by FLOWERING LOCUS T Requires Direct Repression of BLADE-ON-PETIOLE Genes by the Homeodomain Protein PENNYWISE.
    Plant Physiol., 2015. 169(3): p. 2187-99
    [PMID:26417007]
  5. Bencivenga S,Serrano-Mislata A,Bush M,Fox S,Sablowski R
    Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis.
    Dev. Cell, 2016. 39(2): p. 198-208
    [PMID:27666746]
  6. Sehra B,Franks RG
    Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development.
    Front Plant Sci, 2017. 8: p. 1712
    [PMID:29085379]
  7. Simonini S,Stephenson P,Østergaard L
    A molecular framework controlling style morphology in Brassicaceae.
    Development, 2018.
    [PMID:29440299]