PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016452522.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family MIKC_MADS
Protein Properties Length: 246aa    MW: 28689.9 Da    PI: 9.7732
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016452522.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF95.22.8e-302777151
                    S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
          SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                    krien++nrqvtf+kRrng+lKKA+ELSvLC+ae+a+i+fss+g++yeys+
  XP_016452522.1 27 KRIENNTNRQVTFCKRRNGLLKKAYELSVLCEAEIALIVFSSRGRVYEYSN 77
                    79***********************************************95 PP
2K-box101.21.4e-33971918100
           K-box   8 s..leeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100
                     +  ++e +a+ +qqe++kL+++i+++q+++Rhl+Ge+L+sL+++eL+qLe++Le+++++iRskK+e++l+++e+lqk+e +l++en  Lr+k++e
  XP_016452522.1  97 ActTQELNAQFYQQESKKLRQQIQMIQNSNRHLVGEGLSSLNVRELKQLENRLERGITRIRSKKHEMILAETENLQKREIQLEQENAFLRSKIAE 191
                     24478899************************************************************************************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006633.3471979IPR002100Transcription factor, MADS-box
SMARTSM004328.6E-411978IPR002100Transcription factor, MADS-box
SuperFamilySSF554552.88E-322094IPR002100Transcription factor, MADS-box
CDDcd002652.02E-412092No hitNo description
PROSITE patternPS0035002175IPR002100Transcription factor, MADS-box
PRINTSPR004041.1E-312141IPR002100Transcription factor, MADS-box
PfamPF003191.8E-252875IPR002100Transcription factor, MADS-box
PRINTSPR004041.1E-314156IPR002100Transcription factor, MADS-box
PRINTSPR004041.1E-315677IPR002100Transcription factor, MADS-box
PfamPF014861.0E-26101189IPR002487Transcription factor, K-box
PROSITE profilePS5129715.891105195IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0080155Biological Processregulation of double fertilization forming a zygote and endosperm
GO:0090376Biological Processseed trichome differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 246 aa     Download sequence    Send to blast
MCTKFPLCMR FGEKPDHKMG RGKIEIKRIE NNTNRQVTFC KRRNGLLKKA YELSVLCEAE  60
IALIVFSSRG RVYEYSNNNI KATIDRYKKA TSETSNACTT QELNAQFYQQ ESKKLRQQIQ  120
MIQNSNRHLV GEGLSSLNVR ELKQLENRLE RGITRIRSKK HEMILAETEN LQKREIQLEQ  180
ENAFLRSKIA ENERLQELSM MPTGGQDYSA IQQYLARNML QLNMMEGGIP SYHQLPTDKK  240
SLELHE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tqe_P5e-201987169Myocyte-specific enhancer factor 2B
1tqe_Q5e-201987169Myocyte-specific enhancer factor 2B
1tqe_R5e-201987169Myocyte-specific enhancer factor 2B
1tqe_S5e-201987169Myocyte-specific enhancer factor 2B
6c9l_A5e-201987169Myocyte-specific enhancer factor 2B
6c9l_B5e-201987169Myocyte-specific enhancer factor 2B
6c9l_C5e-201987169Myocyte-specific enhancer factor 2B
6c9l_D5e-201987169Myocyte-specific enhancer factor 2B
6c9l_E5e-201987169Myocyte-specific enhancer factor 2B
6c9l_F5e-201987169Myocyte-specific enhancer factor 2B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in seed development (PubMed:21447172, Ref.1, PubMed:29853599). Plays a role in seed morphogenesis by promoting the correct development of endotesta cell layer, which directs the further development of the seed coat, the endosperm, and consequently the embryo (Ref.1, PubMed:29853599). {ECO:0000269|PubMed:21447172, ECO:0000269|PubMed:29853599, ECO:0000269|Ref.1}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankX816510.0X81651.1 P.hybrida mRNA for MADS box containing protein.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016452522.10.0PREDICTED: agamous-like MADS-box protein AGL11
SwissprotF6I4571e-114AG11C_VITVI; Agamous-like MADS-box protein AGL11
TrEMBLA0A1S3YKP80.0A0A1S3YKP8_TOBAC; agamous-like MADS-box protein AGL11
STRINGXP_009770275.11e-165(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA4024625
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G09960.11e-100MIKC_MADS family protein
Publications ? help Back to Top
  1. Jaillon O, et al.
    The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla.
    Nature, 2007. 449(7161): p. 463-7
    [PMID:17721507]
  2. Díaz-Riquelme J,Lijavetzky D,Martínez-Zapater JM,Carmona MJ
    Genome-wide analysis of MIKCC-type MADS box genes in grapevine.
    Plant Physiol., 2009. 149(1): p. 354-69
    [PMID:18997115]
  3. Mejía N, et al.
    Molecular, genetic and transcriptional evidence for a role of VvAGL11 in stenospermocarpic seedlessness in grapevine.
    BMC Plant Biol., 2011. 11: p. 57
    [PMID:21447172]
  4. Grimplet J,Martínez-Zapater JM,Carmona MJ
    Structural and functional annotation of the MADS-box transcription factor family in grapevine.
    BMC Genomics, 2016. 17: p. 80
    [PMID:26818751]
  5. Malabarba J, et al.
    The MADS-box gene Agamous-like 11 is essential for seed morphogenesis in grapevine.
    J. Exp. Bot., 2017. 68(7): p. 1493-1506
    [PMID:28369525]
  6. Royo C, et al.
    The Major Origin of Seedless Grapes Is Associated with a Missense Mutation in the MADS-Box Gene VviAGL11.
    Plant Physiol., 2018. 177(3): p. 1234-1253
    [PMID:29853599]