PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016453845.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 198aa MW: 22796.6 Da PI: 8.9269

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016453845.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	57.8	2.2e-18	135	181	2	45
--SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSST CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedp 45 dDgy+WrKYGqK+ g+++prsYYrC+++ +C+++k ++ +++p XP_016453845.1 135 DDGYSWRKYGQKDTFGAKYPRSYYRCAHRymqNCEATKYIQSLKQQP 181 8*************************9999*******998876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.5E-18	126	182	IPR003657	WRKY domain
PROSITE profile	PS50811	16.157	129	175	IPR003657	WRKY domain
SuperFamily	SSF118290	9.29E-17	132	183	IPR003657	WRKY domain
SMART	SM00774	9.2E-17	134	190	IPR003657	WRKY domain
Pfam	PF03106	9.3E-16	135	179	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 198 aa Download sequence Send to blast
MDFSINPEYN SLINELTQGM EHTKQLRAYL RTVPSTSETT QEVLLQKIIY SYEQSLLILK 60 WSGSTPKSSL PLPPTIGAIE SPSFANGSPK SDDMKRSFIH HPELIDNSKR SKKSQPIWSE 120 EVRVSAESGS EGPIDDGYSW RKYGQKDTFG AKYPRSYYRC AHRYMQNCEA TKYIQSLKQQ 180 PNEWFWNSSQ LATFRIIP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:20409006). May regulate the early events of leaf senescence (PubMed:17369373, PubMed:20409006). Negatively regulates the expression of ESR/ESP (PubMed:20409006). Together with WRKY46 and WRKY70, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). {ECO:0000269\|PubMed:17369373, ECO:0000269\|PubMed:20409006, ECO:0000269\|PubMed:22325892}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Strong accumulation during leaf senescence (PubMed:22268143). Down-regulated by jasmonate. Triggered by P.syringae (PubMed:22325892). {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11506370, ECO:0000269\|PubMed:17369373, ECO:0000269\|PubMed:22268143, ECO:0000269\|PubMed:22325892}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016453845.1	1e-147	PREDICTED: probable WRKY transcription factor 53 isoform X2
Swissprot	Q9SUP6	2e-35	WRK53_ARATH; Probable WRKY transcription factor 53
TrEMBL	A0A1S3YPD0	1e-145	A0A1S3YPD0_TOBAC; probable WRKY transcription factor 53 isoform X2
STRING	XP_009628594.1	1e-125	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G23810.1	9e-35	WRKY family protein

Publications ? help Back to Top
Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Zhang H, et al. Arabidopsis AtERF15 positively regulates immunity against Pseudomonas syringae pv. tomato DC3000 and Botrytis cinerea. Front Plant Sci, 2015. 6: p. 686 [PMID:26388886] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Chen X, et al. POWERDRESS interacts with HISTONE DEACETYLASE 9 to promote aging in Arabidopsis. Elife, 2017. [PMID:27873573] Nie P, et al. Induced Systemic Resistance against Botrytis cinerea by Bacillus cereus AR156 through a JA/ET- and NPR1-Dependent Signaling Pathway and Activates PAMP-Triggered Immunity in Arabidopsis. Front Plant Sci, 2017. 8: p. 238 [PMID:28293243] Ren Y,Li Y,Jiang Y,Wu B,Miao Y Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. Mol Plant, 2017. 10(5): p. 749-763 [PMID:28412544] Sarkar S, et al. Interaction of Arabidopsis TGA3 and WRKY53 transcription factors on Cestrum yellow leaf curling virus (CmYLCV) promoter mediates salicylic acid-dependent gene expression in planta. Planta, 2018. 247(1): p. 181-199 [PMID:28913593] Crespo-Salvador Ó,Escamilla-Aguilar M,López-Cruz J,López-Rodas G,González-Bosch C Determination of histone epigenetic marks in Arabidopsis and tomato genes in the early response to Botrytis cinerea. Plant Cell Rep., 2018. 37(1): p. 153-166 [PMID:29119291] Yuan N, et al. STRESS INDUCED FACTOR 2, a Leucine-Rich Repeat Kinase Regulates Basal Plant Pathogen Defense. Plant Physiol., 2018. 176(4): p. 3062-3080 [PMID:29463771]