PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016469257.1
Common NameAn1b
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 662aa    MW: 73296.8 Da    PI: 5.024
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016469257.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH43.84.6e-14462507454
                     HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                     +h  +ErrRR+++N++f  Lr+l+P       +K++Ka+iL  ++eY+k+L
  XP_016469257.1 462 NHVLAERRRREKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQL 507
                     7999**********************8.....8*****************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142154.1E-3510154IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.688458507IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.44E-18462522IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.2E-11462507IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.13E-15462512No hitNo description
Gene3DG3DSA:4.10.280.103.8E-19462524IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.9E-18464513IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010026Biological Processtrichome differentiation
GO:0010214Biological Processseed coat development
GO:2000029Biological Processregulation of proanthocyanidin biosynthetic process
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 662 aa     Download sequence    Send to blast
MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCSQQGVLVW RDGYYNGAIK TRKTVQPMEV  60
SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI  120
GLPGKAYSKK HHIWIMCANE VDSKVFCRAI LAKVQEDIGF INHVKSFFTE QQQPQPPKPA  180
LSEHSTSNST TFSEPHFYSG NTPPSGNADI AQQDGGAAGE EDEEEEEEED DEAELDSDSI  240
AIQSEVGGAA NPIAAEASEL MQLDMSEAIR LGSPDDGSNN MDSDFHLVGA GNTADYQRQP  300
DSFKAETAIS WAHFQDLQHL PGGSSYEELS QEDTHYSQTV STILEHFSNR SSKFSSTTMG  360
CISHDSAQSA FTLCPSTTVD CSPNPAHCRR RHDDSLLDGG GASPSSQWLL KSILFTVPFL  420
HTKYQSEASP KSVDVATVDS SSTASRFRKG CSITSQEEPS GNHVLAERRR REKLNERFII  480
LRSLVPFVTK MDKASILGDT IEYVKQLHKK VQDLEARARH TEQSKDAVTK DQKSGTATVK  540
VLQGRGKRRM NTVEAGNIGG GQAKMTAFPL STTEDEEVVQ VEVSIIESDA LLELRCPYKE  600
GLLLDVMQML RELKVEVVAI QSSLNNGIFL AELRAKVKEN IYGRKASIVE VKKSIHQIIP  660
RD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rru_A7e-131013548174Transcription factor MYC3
4ywc_A7e-131013548174Transcription factor MYC3
4ywc_B7e-131013548174Transcription factor MYC3
5gnj_A7e-14456516362Transcription factor MYC2
5gnj_B7e-14456516362Transcription factor MYC2
5gnj_E7e-14456516362Transcription factor MYC2
5gnj_F7e-14456516362Transcription factor MYC2
5gnj_G7e-14456516362Transcription factor MYC2
5gnj_I7e-14456516362Transcription factor MYC2
5gnj_M7e-14456516362Transcription factor MYC2
5gnj_N7e-14456516362Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1466471ERRRRE
2467472RRRREK
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator involved in the control of flavonoid pigmentation. {ECO:0000269|PubMed:20949001}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHQ5892090.0HQ589209.1 Nicotiana tabacum anthocyanin 1b (An1b) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016469257.10.0PREDICTED: basic helix-loop-helix protein A-like isoform X4
SwissprotE3SXU40.0BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBLA0A1S3ZXY10.0A0A1S3ZXY1_TOBAC; basic helix-loop-helix protein A-like isoform X4
STRINGXP_009602346.10.0(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G09820.12e-74bHLH family protein
Publications ? help Back to Top
  1. Hellens RP, et al.
    Identification of Mendel's white flower character.
    PLoS ONE, 2010. 5(10): p. e13230
    [PMID:20949001]
  2. Bai Y, et al.
    Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active.
    Planta, 2011. 234(2): p. 363-75
    [PMID:21484270]