PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016472275.1
Common NameERF189
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family ERF
Protein Properties Length: 232aa    MW: 26149 Da    PI: 6.3673
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016472275.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP245.91.4e-14106159155
             AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                     ++y GV +++ +g + Ae rdps  g   +r +lg++ tae+Aa a+++a+ k++g
  XP_016472275.1 106 TRYIGVKRRP-WGTFSAETRDPSRKG-EgARLWLGTYETAEDAALAYDQAAFKIRG 159
                     589****9*9.**********85533.35*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000189.69E-26106169No hitNo description
PfamPF008471.5E-10106159IPR001471AP2/ERF domain
SuperFamilySSF541714.64E-18107168IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.102.3E-26107168IPR001471AP2/ERF domain
SMARTSM003808.9E-28107173IPR001471AP2/ERF domain
PROSITE profilePS5103221.535107167IPR001471AP2/ERF domain
PRINTSPR003678.8E-8108119IPR001471AP2/ERF domain
PRINTSPR003678.8E-8133149IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 232 aa     Download sequence    Send to blast
MEMNLADETL FFSESHLLES IKQHLLDDSD FSEIFSPMSS SNEILPNSPS SSFSSFDCSF  60
LNWDENFEET LIPTDQNPSH EKCSESEEQT QGPAVVREKN APRDWTRYIG VKRRPWGTFS  120
AETRDPSRKG EGARLWLGTY ETAEDAALAY DQAAFKIRGS RARLNFPHLI GSNMPKPARV  180
TARRSRTRSP EPSSSSSTSS SENVPRKRNI DVINSIAKAK FLCHSLNLQR LA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A8e-24108167360ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A1e-23108172668ATERF1
3gcc_A1e-23108172668ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional activator and may be involved in disease resistance pathways. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase cascade, and to be influenced by methyl-jasmonate. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:10792818, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by ethephon (ethylene-releasing compound) in buds and to a lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemic expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Wound induction is reduced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by both protein kinases and protein phosphatases. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:12090623, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB8279510.0AB827951.1 Nicotiana tabacum ERF189 mRNA for ethylene response factor 189, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001312507.11e-171ethylene-responsive transcription factor 13-like
RefseqXP_009625878.11e-171PREDICTED: ethylene-responsive transcription factor 13-like
SwissprotQ404794e-36ERF2_TOBAC; Ethylene-responsive transcription factor 2
TrEMBLA0A060N1851e-170A0A060N185_TOBAC; Ethylene response factor 189
STRINGXP_009625878.11e-171(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA21241165
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G44840.12e-22ethylene-responsive element binding factor 13
Publications ? help Back to Top
  1. Nakano T,Nishiuchi T,Suzuki K,Fujimura T,Shinshi H
    Studies on transcriptional regulation of endogenous genes by ERF2 transcription factor in tobacco cells.
    Plant Cell Physiol., 2006. 47(4): p. 554-8
    [PMID:16452120]
  2. Shoji T,Kajikawa M,Hashimoto T
    Clustered transcription factor genes regulate nicotine biosynthesis in tobacco.
    Plant Cell, 2010. 22(10): p. 3390-409
    [PMID:20959558]