PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016476596.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 209aa    MW: 23480 Da    PI: 9.6737
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016476596.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH26.51.1e-08126166954
                     HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
             HLH   9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                      r RR+ri +++  L++l+P       +K++ a++L +Av+Y+k L
  XP_016476596.1 126 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAVHYVKFL 166
                     699*****************87.....8****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.345117166IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.3E-14118180IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.01E-14121176IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.2E-13123172IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.0E-6127166IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000835.49E-6140171No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 209 aa     Download sequence    Send to blast
MNLQDIAQSL ELGFSSSNIE MIPLQPPVHK YSNYLMTSPP SNFSFMGNPI EEPNIPILSS  60
IDEIIASAHS SGNEYSCLQN RNSMEAMREM IFRMAMMQPI HIDPQSVKPP KRKNVKISKD  120
PQSVAARHRR ERISERIRIL QRLVPGGTKM DTASMLDEAV HYVKFLKKQL HSLEQAAVNN  180
KPNMVAGFSS TFSPVPMNYN SSSSAQMLS
Functional Description ? help Back to Top
Source Description
UniProtRequired for the female reproductive tract development and fertility. {ECO:0000269|PubMed:17855426}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269|PubMed:17855426}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016476596.11e-152PREDICTED: transcription factor HEC2-like
SwissprotQ9SND41e-47HEC2_ARATH; Transcription factor HEC2
TrEMBLA0A1S4AIX41e-151A0A1S4AIX4_TOBAC; transcription factor HEC2-like
STRINGXP_009605955.11e-150(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA75223101
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G50330.14e-44bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Zhu L, et al.
    A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis.
    Plant Cell, 2016. 28(4): p. 855-74
    [PMID:27073231]