PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016483495.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family ARF
Protein Properties Length: 636aa    MW: 70670 Da    PI: 8.3873
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016483495.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B331.53.2e-1019625398
                    EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE- CS
              B3 53 rkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkvfr 98
                    +++++r++l++GW+ Fv++++L +gD ++F   + +++el+v+v+ 
  XP_016483495.1 19 SGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGENGELRVGVRH 62
                    778999*************************..4499999***985 PP
2Auxin_resp121.85.1e-4088170183
      Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                     a+ha++tk++F+v+Y+Pr+s+++F+v+++++++++k+++s+GmRfkm+fe+e+++e+r++Gt+vg++d dp rWp+SkWr+Lk
  XP_016483495.1  88 AWHAIQTKTMFTVYYKPRTSPADFIVPYDQYMESVKNNYSIGMRFKMRFEGEEAPEQRFTGTIVGIEDGDPNRWPESKWRCLK 170
                     89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS508638.952164IPR003340B3 DNA binding domain
SuperFamilySSF1019361.22E-101891IPR015300DNA-binding pseudobarrel domain
CDDcd100172.47E-61861No hitNo description
Gene3DG3DSA:2.40.330.107.5E-151877IPR015300DNA-binding pseudobarrel domain
PfamPF023621.9E-71962IPR003340B3 DNA binding domain
PfamPF065076.3E-3788170IPR010525Auxin response factor
PfamPF023096.3E-10531622IPR033389AUX/IAA domain
SuperFamilySSF542777.36E-12536615No hitNo description
PROSITE profilePS5174521.79538622IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 636 aa     Download sequence    Send to blast
LVVPVMFPTF CFHAISQISG QPRRHLLQSG WSVFVSSKRL VAGDAFIFLR GENGELRVGV  60
RHAMRQQGNA PSSVISSHSM HLGVLATAWH AIQTKTMFTV YYKPRTSPAD FIVPYDQYME  120
SVKNNYSIGM RFKMRFEGEE APEQRFTGTI VGIEDGDPNR WPESKWRCLK VRWDETSAIP  180
RPDRVSPWKI EPALSPPALN PLPIPRPKRP RSNVLPSSPD SSVLTREGSS KRTAGPSQAS  240
GFSRVLQGQE ISTLRGNFVE NNGSDSSEKP IVWPPSLDDE KTDVHSASRR CLSDKWLPLG  300
RPESSFTDLL SGFGVQVSSS HGLHLPAGGQ TALPASLVKR QALDKENDFS LLGKQWSLAS  360
SGLSLNLMDS GLKGADTLYQ MRETSKCSGF NEYPTLPGHR IDNQQGNWLM PQSVLPYIQM  420
STHSGEIMPK PMALLQPEAV KPKEGNCKLF GIPLVSKSAS IDPVKLQNNS LIDSASNMHF  480
GIHPHQFPAT ESDLRSEQSK GSKVLDNGIT VNDQEKQFQT SHLGTRDREG KGLINSTRSC  540
TKVHKHGTAL GRSVDLAKFN NYEELIAELD HLFYFNGELK AQNKNWLVVY TDDEGDMMLV  600
GDDPWQEFCG MVCKIFIYTK EEVQRMNPGS LNSKGS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A9e-8120192182354Auxin response factor 1
4ldw_A9e-8120192182354Auxin response factor 1
4ldw_B9e-8120192182354Auxin response factor 1
4ldx_A1e-8020192182354Auxin response factor 1
4ldx_B1e-8020192182354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor. Involved in the control of fruit ripening process. Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26716451, PubMed:26959229). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression is up-regulated by plant hormone auxin in tomato fruits. {ECO:0000269|PubMed:26716451}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHM1439400.0HM143940.1 Solanum lycopersicum auxin response factor 11-like (ARF11) mRNA, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016483495.10.0PREDICTED: auxin response factor 2-like, partial
SwissprotK4DF010.0ARF2B_SOLLC; Auxin response factor 2B
TrEMBLA0A1S4B3J40.0A0A1S4B3J4_TOBAC; Auxin response factor
STRINGXP_009798135.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA26182444
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]