PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016492389.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family WRKY
Protein Properties Length: 590aa    MW: 66026.6 Da    PI: 8.325
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016492389.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY106.81.1e-33266323260
                     --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
            WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                     +DgynWrKYGqK+vkgse+prsYY+Ct+++Cp+kkkvers  d++++ei+Y+g+Hnh+k
  XP_016492389.1 266 EDGYNWRKYGQKQVKGSENPRSYYKCTFPNCPTKKKVERSL-DGQITEIVYKGNHNHPK 323
                     7****************************************.***************85 PP
2WRKY106.41.4e-33432490159
                     ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                     ldDgy+WrKYGqK+vkg+++prsYY+Cts+gCpv+k+ver+++d + v++tYeg+Hnh+
  XP_016492389.1 432 LDDGYRWRKYGQKVVKGNPNPRSYYKCTSPGCPVRKHVERASQDIRSVITTYEGKHNHD 490
                     59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.804.1E-29253324IPR003657WRKY domain
PROSITE profilePS5081123.743260324IPR003657WRKY domain
SuperFamilySSF1182901.96E-25261324IPR003657WRKY domain
SMARTSM007741.1E-36265323IPR003657WRKY domain
PfamPF031062.1E-25266322IPR003657WRKY domain
Gene3DG3DSA:2.20.25.802.0E-37417492IPR003657WRKY domain
SuperFamilySSF1182905.1E-29424492IPR003657WRKY domain
PROSITE profilePS5081138.595427492IPR003657WRKY domain
SMARTSM007741.1E-38432491IPR003657WRKY domain
PfamPF031061.1E-25433490IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 590 aa     Download sequence    Send to blast
MEKQHSALQN TCSFFLLISH PLPQSQDHHI IQSSFLSLFL LIKPIMAASS TIIDTSSMQN  60
SSFSFPTSSS SFMTSSFTEL LASDDYPTKS KGLGDRIAER TGSGVPKFKS LPPPSLPLSP  120
PPFSPSSYFA IPPGLSPTEL LDSPVLLSAS NILPSPTTGT FPAQAFNWKS SRHQGVKQED  180
KNYSDFSFQP QFGQSFPSVS PSQTNLVPLK KQSWNYQESR NQNDQSSENA NGRTEFNTMQ  240
SLKNNGQSNQ YNNQSSQSIR EQKRSEDGYN WRKYGQKQVK GSENPRSYYK CTFPNCPTKK  300
KVERSLDGQI TEIVYKGNHN HPKPQSTRRS SSTASSLTVQ PYSTQTNEIP DHQSYGSNAT  360
PENSSISFGD DDHDHEQSSQ KSRSRGDDNE EEEPDSKRWK RESESEGLSA PGSRTVREPR  420
VVVQTTSDID ILDDGYRWRK YGQKVVKGNP NPRSYYKCTS PGCPVRKHVE RASQDIRSVI  480
TTYEGKHNHD VPAARGSGIN RPVAPNITYN NGANAMAIRP SVTSQIPLQS IRPQQSPFTL  540
EMLHKPSNYN GFSGYVNSED SYENQLQDNN VFSRAKDEPR DDMFMETLLC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-34257493878Probable WRKY transcription factor 4
2lex_A2e-34257493878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4453920.0AB445392.1 Nicotiana benthamiana NbWRKY8 mRNA for double WRKY type transfactor, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016492389.10.0PREDICTED: probable WRKY transcription factor 33
SwissprotQ6IEQ71e-130WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A1S4BU310.0A0A1S4BU31_TOBAC; probable WRKY transcription factor 33
STRINGXP_009790461.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA22862460
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.11e-111WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]