PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016499286.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 254aa MW: 28123.6 Da PI: 8.6624

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016499286.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.1	1.6e-08	161	201	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L XP_016499286.1 161 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 201 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.218	152	201	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.8E-13	157	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.4E-14	157	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.3E-14	158	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	7.4E-6	162	201	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.45E-6	175	206	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 254 aa Download sequence Send to blast
MDIEMLKSAT ASEDQMELML MMQLDKLPDF STGNCSELPM MDFSPQGSCN SNSSGNGNTN 60 YFPHQIDHNS PNFLNIPSTN ISFTNSYQNP STLQNFLANN SSSSSSGAYN SHSMNRSNMA 120 AMREMIFRIA AMQPINIDPE SVKPPKRRNV KISTDPQSVA ARHRRERISE RIRILQRLVP 180 GGTKMDTASM LDEAIHYVKF LKNQVQSLER AGANRPSNSV AATGLGFPVP MSLSGNYLPV 240 SSKSYQNIQQ YADA

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975516	1e-107	HG975516.1 Solanum lycopersicum chromosome ch04, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009796053.1	0.0	PREDICTED: transcription factor HEC1-like
Refseq	XP_016499286.1	0.0	PREDICTED: transcription factor HEC1-like
Swissprot	Q9FHA7	3e-48	HEC1_ARATH; Transcription factor HEC1
TrEMBL	A0A1S4CDU8	0.0	A0A1S4CDU8_TOBAC; transcription factor HEC1-like
TrEMBL	A0A1U7XYR2	0.0	A0A1U7XYR2_NICSY; transcription factor HEC1-like
STRING	XP_009796053.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	4e-42	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Vercruyssen L, et al. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell, 2014. 26(1): p. 210-29 [PMID:24443518] Sparks EE,Benfey PN HEC of a job regulating stem cells. Dev. Cell, 2014. 28(4): p. 349-50 [PMID:24576420] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667]