PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016502533.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 469aa MW: 52349.1 Da PI: 7.8075

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016502533.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.4	3.9e-30	234	293	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt + +Cpv+k+v+r+ ed +++++tYeg+Hnh+ XP_016502533.1 234 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVSpSCPVRKQVQRCFEDMSILITTYEGTHNHP 293 58************************999**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.9E-31	219	295	IPR003657	WRKY domain
SuperFamily	SSF118290	1.57E-27	227	295	IPR003657	WRKY domain
PROSITE profile	PS50811	28.644	229	295	IPR003657	WRKY domain
SMART	SM00774	2.9E-36	234	294	IPR003657	WRKY domain
Pfam	PF03106	1.5E-26	235	293	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 469 aa Download sequence Send to blast
MIIFIYADLV SMSRGSFGNS LSTRRGRGKA TLTTTMNTNS RDSSLTYKKN QEDQLNSTKA 60 QIGEAKEENE KLKSMLSKIM KDYQSLQMHF QGISHKPQNS KDIIATSIEQ EEEVDLVSLS 120 LGRSSREFKQ DEKEYDQNEC KDIKKQSKLF DGLELGLDCR FSLDFTEVTK NYDDSPENSF 180 EESKKEHITE PCVQNYTSSK MPRICGDEDE DFLQQNPQKK ARVSIRAVCD TTTMNDGCQW 240 RKYGQKIAKG NPCPRAYYRC TVSPSCPVRK QVQRCFEDMS ILITTYEGTH NHPLPFSATA 300 MASTTSAAAS MLSCTSSSTS QQGITDANNN NLNGFNFTTS NCNNLATHAP NTFYLPKTSI 360 STSQTHPTIT LDFTTVPATT SSSTHTFSSQ RYSSTSLNFS TLPSTPPSSS FINSFKSQVG 420 ASYLGRPCFS QPFTSNNTRN TEDSDGARNS NMWIQKRSKV SHLGFDSVT

Sequence ? help Back to Top

Protein Sequence Length: 469 aa Download sequence Send to blast

MIIFIYADLV SMSRGSFGNS LSTRRGRGKA TLTTTMNTNS RDSSLTYKKN QEDQLNSTKA  60
QIGEAKEENE KLKSMLSKIM KDYQSLQMHF QGISHKPQNS KDIIATSIEQ EEEVDLVSLS  120
LGRSSREFKQ DEKEYDQNEC KDIKKQSKLF DGLELGLDCR FSLDFTEVTK NYDDSPENSF  180
EESKKEHITE PCVQNYTSSK MPRICGDEDE DFLQQNPQKK ARVSIRAVCD TTTMNDGCQW  240
RKYGQKIAKG NPCPRAYYRC TVSPSCPVRK QVQRCFEDMS ILITTYEGTH NHPLPFSATA  300
MASTTSAAAS MLSCTSSSTS QQGITDANNN NLNGFNFTTS NCNNLATHAP NTFYLPKTSI  360
STSQTHPTIT LDFTTVPATT SSSTHTFSSQ RYSSTSLNFS TLPSTPPSSS FINSFKSQVG  420
ASYLGRPCFS QPFTSNNTRN TEDSDGARNS NMWIQKRSKV SHLGFDSVT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	2e-20	226	295	2	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016502533.1	0.0	PREDICTED: probable WRKY transcription factor 72 isoform X1
Swissprot	A0A3Q7GFB5	7e-89	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1S4CMR3	0.0	A0A1S4CMR3_TOBAC; probable WRKY transcription factor 72 isoform X1
STRING	XP_009798626.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	6e-59	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]