PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016510911.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 89aa MW: 9968.23 Da PI: 4.4866

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016510911.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	19	2.5e-06	14	54	14	54
HHHHHHHHHHHCTSCCC...TTS-.STCHHHHHHHHHHHHHH CS HLH 14 driNsafeeLrellPkaskapskK.lsKaeiLekAveYIksL 54 d+iN+ +L++llP++ + +++ + i+e++++YI++L XP_016510911.1 14 DEINDLVLKLQSLLPNS-SSRCTStVPAPKIVEETCNYIRML 54 78************6.36777779999*********99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	9.743	1	54	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	9.42E-8	13	73	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	9.9E-6	13	69	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 89 aa Download sequence Send to blast
MSSSRRSSSR FSQDEINDLV LKLQSLLPNS SSRCTSTVPA PKIVEETCNY IRMLHNEVDD 60 LSERLSQILA SVDTNTVDLL DTLISLLQQ

Functional Description ? help Back to Top
Source	Description
UniProt	Atypical and probable non DNA-binding bHLH transcription factor required for MONOPTEROS-dependent root initiation in embryo. Promotes the correct definition of the hypophysis cell division plane. Transcriptionally controlled by MONOPTEROS. Moves from its site of synthesis in pro-embryos cells into the hypophysis. Regulates brassinosteroid (BR) signaling by sequestering negative BR signaling components. May function as positive regulator of gibberellin signaling. May play a role in the regulation of light signaling and possibly auxin signaling. {ECO:0000269\|PubMed:16527868, ECO:0000269\|PubMed:20023194, ECO:0000269\|PubMed:20220754, ECO:0000269\|PubMed:22339648}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by exogenous gibberellin. {ECO:0000269\|PubMed:16527868}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009616651.1	2e-56	PREDICTED: transcription factor ILI5-like
Refseq	XP_016510911.1	2e-56	PREDICTED: transcription factor ILI5-like
Swissprot	Q9CA64	3e-20	PRE3_ARATH; Transcription factor PRE3
TrEMBL	A0A1S4DBY2	5e-55	A0A1S4DBY2_TOBAC; transcription factor ILI5-like
STRING	XP_009616651.1	8e-56	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA353	24	161

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G74500.1	4e-22	activation-tagged BRI1(brassinosteroid-insensitive 1)-suppressor 1

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Lu KJ,De Rybel B,van Mourik H,Weijers D Regulation of intercellular TARGET OF MONOPTEROS 7 protein transport in the Arabidopsis root. Development, 2018. [PMID:29358212] Baesso B, et al. Transcription factors PRE3 and WOX11 are involved in the formation of new lateral roots from secondary growth taproot in A. thaliana. Plant Biol (Stuttg), 2018. 20(3): p. 426-432 [PMID:29450949]