PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016512542.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 155aa MW: 17830.9 Da PI: 10.4732

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016512542.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.1	7.8e-09	56	96	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR++i +++ L++l+P +K++ a++L +Av+Y+k L XP_016512542.1 56 ARHRREKISERIRILQRLVPGG-----TKMDTASMLDEAVHYVKFL 96 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.358	47	96	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.8E-14	48	106	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.31E-9	49	101	No hit	No description
SuperFamily	SSF47459	1.15E-14	50	107	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.2E-13	53	102	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.5E-6	57	96	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 155 aa Download sequence Send to blast
MHDETLDIEK RSSMDAMREM VFRMAMMQPI HIDPESVKPP KRKNAKISKD PQSVAARHRR 60 EKISERIRIL QRLVPGGTKM DTASMLDEAV HYVKFLKKQL KSLEQAAVNR PMVSGFSPKL 120 LAQPVDYLSS FRSCQTPQLM SSNVQMLYKL SEVKE

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009798816.1	1e-110	PREDICTED: transcription factor HEC2-like
Refseq	XP_016512542.1	1e-111	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	3e-46	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A1S4DGD2	1e-109	A0A1S4DGD2_TOBAC; transcription factor HEC2-like
TrEMBL	A0A1U7YA47	1e-109	A0A1U7YA47_NICSY; transcription factor HEC2-like
STRING	XP_009798816.1	1e-109	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	1e-48	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]