PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016646989.1

Organism

Prunus mume

Taxonomic ID

102107

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus

Family

E2F/DP

Protein Properties

Length: 184aa MW: 20587.9 Da PI: 5.1884

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016646989.1	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	30.5	5.9e-10	115	162	1	46
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse..dvknkrRRi 46 r ++sL+llt+kf++l++++e+gi++ln++a++L ++ + ++ RR+ XP_016646989.1 115 RFDSSLGLLTKKFINLIKHAEDGILDLNNAADTLEAQveNLSDEERRL 162 6789******************************44377666677875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF48452	2.39E-5	4	39	IPR011990	Tetratricopeptide-like helical domain
Gene3D	G3DSA:1.10.10.10	1.7E-8	113	161	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	0.0074	115	170	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.0E-6	117	162	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	1.62E-6	146	184	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 184 aa Download sequence Send to blast
MPELLWKAYI DFELSEGEFE RARELYERLL DRTKHLKLKR KSDAADYEAE SSDRTAATGY 60 TEAVTSPLQT PVSSKVGRAN KTSRLTKCSR SGPQTPASNV GSPSGANLTP AGPCRFDSSL 120 GLLTKKFINL IKHAEDGILD LNNAADTLEA QVENLSDEER RLDQQIREMQ ERLRDLSEDE 180 SNKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_016646989.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016646989.1	1e-133	PREDICTED: transcription factor E2FB-like
Swissprot	Q9FV71	2e-36	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A314Z8V3	6e-86	A0A314Z8V3_PRUYE; Transcription factor E2FB isoform X2
TrEMBL	M5WJS3	5e-86	M5WJS3_PRUPE; Uncharacterized protein (Fragment)
STRING	XP_008245828.1	7e-89	(Prunus mume)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.3	5e-39	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]