PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zjn_sc00007.1.g05310.1.sm.mk
Organism
Zoysia japonica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia
Family E2F/DP
Protein Properties Length: 339aa    MW: 36933.2 Da    PI: 9.8102
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Zjn_sc00007.1.g05310.1.sm.mkgenomeZGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.22.9e-2358123171
                       E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                                   rk+ksL+ll+++f++l+++ + +++ l+++a++L    v  +rRRiYDi+NVLe+++++ +k+kn ++w+g
  Zjn_sc00007.1.g05310.1.sm.mk  58 RKQKSLGLLCSNFVALYNRDHVEHIGLDKAAQSL---GV--ERRRIYDIVNVLESIGILVRKAKNLYTWIG 123
                                   79*****************999************...**..****************************98 PP
2E2F_TDP76.42.8e-24202281170
                       E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwk 70 
                                   rkeksL+lltq+f+kl+ ++e ++++l+e++k L+ e     ++++k+RR+YDi+NVL++lnl+ek     ++k+++rw 
  Zjn_sc00007.1.g05310.1.sm.mk 202 RKEKSLGLLTQNFVKLFLTKEVDTISLDEASKLLLGEgheetNMRTKVRRLYDIANVLSSLNLLEKvhqanTKKPAFRWL 281
                                   79*****************999************************************************999******6 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.1E-2654124IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.35E-1657122IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.0E-2858123IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.5E-2059123IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.4E-22199282IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.0E-31202282IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.9E-19203281IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-11204281IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 339 aa     Download sequence    Send to blast
MATTPAMAAA ASSVAQACAA AAAAAAGMES ALWQQERPRA KVAEGGGPKG ARHHAYSRKQ  60
KSLGLLCSNF VALYNRDHVE HIGLDKAAQS LGVERRRIYD IVNVLESIGI LVRKAKNLYT  120
WIGFDGIPIA LRELKDRALR EKSGLAPSQM EQLSAANVSD DEDDDKLGDT DGDTDSEKLS  180
QTVDNPSDKP GASQCRLRSD HRKEKSLGLL TQNFVKLFLT KEVDTISLDE ASKLLLGEGH  240
EETNMRTKVR RLYDIANVLS SLNLLEKVHQ ANTKKPAFRW LAKAGKPKTE TGVAFAVSPS  300
AKSRLVIFFP ITLKLGSLGI LIWRKAATLC GNTWGSQER
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-37572693223Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022682371.11e-154E2F transcription factor-like E2FE
SwissprotQ8LSZ44e-77E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A368PRM91e-153A0A368PRM9_SETIT; Uncharacterized protein
STRINGSi019635m1e-149(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.11e-78DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]