PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zpz_sc01706.1.g00120.1.sm.mkhc
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia
Family E2F/DP
Protein Properties Length: 326aa    MW: 35560.1 Da    PI: 8.6966
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Zpz_sc01706.1.g00120.1.sm.mkhcgenomeZGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP56.73.9e-1889147871
                         E2F_TDP   8 lltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                                      l+ +f++l+ +++ ++v l+++ak+L    v  +rRRiYDi+NVLe+++++ +++kn++ w g
  Zpz_sc01706.1.g00120.1.sm.mkhc  89 RLSCSFVALYDREDVEAVGLDDAAKRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYAWLG 147
                                     58899******9999************...**..****************************87 PP

2E2F_TDP726.5e-23204270162
                         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliekk 62 
                                     rkeksL+lltq+f+kl+ + e ++++l+e+a+ L+ e     ++++k+RR+YDi+NVL++lnliek 
  Zpz_sc01706.1.g00120.1.sm.mkhc 204 RKEKSLGLLTQNFVKLFLTMEVETISLDEAARLLLGEghaesNMRTKVRRLYDIANVLSSLNLIEKL 270
                                     79****************************************************************4 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.9E-204560IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.9E-2349147IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.0E-1689147IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.04E-1389146IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.9E-2094148IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.7E-19201270IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.7E-23204281IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467855.85E-11204272IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023198.6E-18205270IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 326 aa     Download sequence    Send to blast
MDAAAAAAVA GPSSSSGAGA SAQPQPKVPQ AAVQGAAASK SCRHHAYSRK QKSLGLLCSK  60
CAPFSFRSRL SLARDARSGR SVALTQVSRL SCSFVALYDR EDVEAVGLDD AAKRLGVERR  120
RIYDIVNVLE SVGILVRRAK NRYAWLGFGG VTAALKELKA SDDEDDDKLG DADEDNENEK  180
LSQSVDNLSD KPGALPCRLR SDHRKEKSLG LLTQNFVKLF LTMEVETISL DEAARLLLGE  240
GHAESNMRTK VRRLYDIANV LSSLNLIEKL GQGSRSDFVY GPFHPSGAKK QEIGDHSARE  300
ERKSIQDWEN LAVTFRPQYQ NQVVGL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-32482703222Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapZpz_sc01706.1.g00120.1.sm.mkhc
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002436789.11e-115E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ48e-65E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLC5Z7K61e-114C5Z7K6_SORBI; Uncharacterized protein
STRINGSb10g008800.11e-115(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.12e-62DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]