PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_10077_iso_7

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

M-type_MADS

Protein Properties

Length: 89aa MW: 10312.3 Da PI: 10.1145

Description

M-type_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_10077_iso_7	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	101.3	3.7e-32	28	78	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fss+g++yey++ cra_locus_10077_iso_7_len_264_ver_3 28 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRVYEYAN 78 79***********************************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	4.0E-41	20	79	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	33.207	20	80	IPR002100	Transcription factor, MADS-box
CDD	cd00265	3.01E-43	21	88	No hit	No description
SuperFamily	SSF55455	8.89E-33	21	88	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	22	76	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	1.5E-33	22	42	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	1.4E-27	29	76	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	1.5E-33	42	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	1.5E-33	57	78	IPR002100	Transcription factor, MADS-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 89 aa Download sequence Send to blast
XMGMGCPNQE FHESSQLRKT GRGKIEIKRI ENTTNRQVTF CKRRNGLLKK AYELSVLCDA 60 EVALIVFSSR GRVYEYANNN IRSTIDRYX

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1egw_A	1e-21	21	88	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_B	1e-21	21	88	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_C	1e-21	21	88	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_D	1e-21	21	88	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1tqe_P	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
1tqe_Q	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
1tqe_R	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
1tqe_S	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
3mu6_A	1e-21	21	88	1	68	Myocyte-specific enhancer factor 2A
3mu6_B	1e-21	21	88	1	68	Myocyte-specific enhancer factor 2A
3mu6_C	1e-21	21	88	1	68	Myocyte-specific enhancer factor 2A
3mu6_D	1e-21	21	88	1	68	Myocyte-specific enhancer factor 2A
6c9l_A	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
6c9l_B	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
6c9l_C	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
6c9l_D	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
6c9l_E	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
6c9l_F	1e-21	21	88	2	69	Myocyte-specific enhancer factor 2B
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Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the control of organ identity during the early development of flowers. Is required for normal development of stamens and carpels in the wild-type flower. Plays a role in maintaining the determinacy of the floral meristem. Acts as C class cadastral protein by repressing the A class floral homeotic genes like APETALA1. Forms a heterodimer via the K-box domain with either SEPALATTA1/AGL2, SEPALATTA2/AGL4, SEPALLATA3/AGL9 or AGL6 that could be involved in genes regulation during floral meristem development. Controls AHL21/GIK, a multifunctional chromatin modifier in reproductive organ patterning and differentiation (PubMed:19956801). Induces microsporogenesis through the activation of SPL/NZZ (PubMed:15254538). {ECO:0000269\|PubMed:15254538, ECO:0000269\|PubMed:19956801}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by the A class floral homeotic protein APETALA2 and by other repressors like LEUNIG, SEUSS, SAP or CURLY LEAF. Positively regulated by both LEAFY and APETALA1. Repressed by silencing mediated by polycomb group (PcG) protein complex containing EMF1 and EMF2. Up-regulated by HUA2. {ECO:0000269\|PubMed:10198637, ECO:0000269\|PubMed:11058164, ECO:0000269\|PubMed:1675158, ECO:0000269\|PubMed:17794879, ECO:0000269\|PubMed:18281509, ECO:0000269\|PubMed:19783648, ECO:0000269\|PubMed:9783581}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009762632.1	2e-46	PREDICTED: floral homeotic protein AGAMOUS isoform X1
Refseq	XP_016486557.1	2e-46	PREDICTED: floral homeotic protein AGAMOUS-like isoform X1
Refseq	XP_027060990.1	5e-47	floral homeotic protein AGAMOUS-like
Swissprot	P17839	1e-42	AG_ARATH; Floral homeotic protein AGAMOUS
TrEMBL	Q08711	5e-46	Q08711_PETHY; Fbp6 protein
TrEMBL	Q40900	4e-46	Q40900_PETIN; Agamous protein
STRING	XP_009762632.1	8e-46	(Nicotiana sylvestris)

Publications ? help Back to Top
Huang Z, et al. APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol., 2017. 215(3): p. 1197-1209 [PMID:27604611] Rong XF, et al. Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 756-764 [PMID:29186581] Uemura A, et al. Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis. Plant Reprod, 2018. 31(1): p. 89-105 [PMID:29218596]