PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_13167_iso_2

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

CAMTA

Protein Properties

Length: 1061aa MW: 117811 Da PI: 5.8833

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_13167_iso_2	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	117.2	8.3e-37	2	73	47	118
CG-1 47 vryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcywlLeeelekivlvhylevk 118 +ryfrkDG++w+kk+dgktv+E+he+LK g+v+vl+cyYah+een++fqrr+yw+Leee+++ivlvhy+evk cra_locus_13167_iso_2_len_3478_ver_3 2 LRYFRKDGHNWRKKRDGKTVKEAHERLKAGSVDVLHCYYAHGEENENFQRRSYWMLEEERSHIVLVHYREVK 73 79*******************************************************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01076	7.0E-29	1	73	IPR005559	CG-1 DNA-binding domain
PROSITE profile	PS51437	55.349	1	78	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	4.5E-30	2	71	IPR005559	CG-1 DNA-binding domain
SuperFamily	SSF81296	3.36E-11	470	556	IPR014756	Immunoglobulin E-set
SuperFamily	SSF48403	1.71E-16	651	767	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	5.55E-13	653	765	No hit	No description
Gene3D	G3DSA:1.25.40.20	1.4E-16	653	768	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50297	16.626	673	777	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	1.5E-7	678	768	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	9.458	706	738	IPR002110	Ankyrin repeat
SMART	SM00248	0.0018	706	735	IPR002110	Ankyrin repeat
SMART	SM00248	250	745	774	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	1.73E-8	877	932	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	0.11	881	903	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.261	883	911	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.002	883	902	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	7.5E-4	904	926	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.578	905	929	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	8.1E-5	907	926	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1061 aa Download sequence Send to blast
XLRYFRKDGH NWRKKRDGKT VKEAHERLKA GSVDVLHCYY AHGEENENFQ RRSYWMLEEE 60 RSHIVLVHYR EVKGNRTNLI RSREATEPIP DAQETEDDIR NSEAGSCSTS KFHPYDYQVA 120 SQVTDTASLN SAQASEYGDA ESAYNHQSSS SFHTYRDLQP PVMQKAEDRH SLPVPSIELV 180 LLVLLFFSFV CVAIVVAFGD EKSKFLLTDT YQVQFPGPPN MGFDPNATST GAPYMPEGQH 240 DFSTWRNVIE SGGLAGQPIN FQTSQVTNSS MMHGLLQQVL TDSLGTEPVS GSRTDGLGQW 300 QTSEGDPLYI SKWPMDQKLH PDSANKLVAS SSEDNIAGLH NSLAPYNVLS ANQNTPQNDL 360 PVHLGGANAG NSSKPAWNSN QTIEGKADYP TMKQVLLDGV LEGGLKKLDS FDRWMSRELG 420 DVNDSHIQSS STNYWESVGN EDDNSNITPP EQIDSYMMGP SLSQDQLFSI IDFAPNWAFS 480 GSEVKVXXXX XXXRAXEEAE KCNWACMFGE LEVPAEVIAN GVLRCSTPLH EPGRVPFYVT 540 CSNRCACSEV REFEFRISSV QNEDVAVMSS VSSEESHLLI RFTKLLTAGS LSNPTNVPGA 600 AGGLSHLTNK VDSSVLDDEN EWACIQNLIS EDKFSVKKVK DQLLQKLLRD KLHLWLIQKV 660 AEDGKGPLIL DEGGQGVLHF AAALGYDWAI PPTIAGGVSV NFRDVNGWTA LHWAASYGRE 720 RTVASLISLD ANPGALTDPT PKYPSGRTPA DLAYSNGHKG IAGYLAESAL SSHLSTIELK 780 DKKDGQDVEN SELKAVQTIT ERTATPSDYG DLPHGLSMKD SLAALRNATQ AAARIHQVFR 840 VQSFQRKQIK EYGDGGSGIS DERALSLLAM RSNRAGHPAE PVHAAAIRIQ NKFRGWKGRK 900 EFLLIRQRII KIQAHVRGHQ VRKNYKKIIW SVGILDKVIL RWRRKGSGLR GFKSEAITEG 960 SGGVERSSKE DDYDFLKEGR KQTEDRLQKA LARVKSMVQY PEARDQYRRL LNVVSEMQET 1020 KTKYDRLLNN SDETAADFDD DLIDIDALLE DDTSMAASSS T

Sequence ? help Back to Top

Protein Sequence Length: 1061 aa Download sequence Send to blast

XLRYFRKDGH NWRKKRDGKT VKEAHERLKA GSVDVLHCYY AHGEENENFQ RRSYWMLEEE  60
RSHIVLVHYR EVKGNRTNLI RSREATEPIP DAQETEDDIR NSEAGSCSTS KFHPYDYQVA  120
SQVTDTASLN SAQASEYGDA ESAYNHQSSS SFHTYRDLQP PVMQKAEDRH SLPVPSIELV  180
LLVLLFFSFV CVAIVVAFGD EKSKFLLTDT YQVQFPGPPN MGFDPNATST GAPYMPEGQH  240
DFSTWRNVIE SGGLAGQPIN FQTSQVTNSS MMHGLLQQVL TDSLGTEPVS GSRTDGLGQW  300
QTSEGDPLYI SKWPMDQKLH PDSANKLVAS SSEDNIAGLH NSLAPYNVLS ANQNTPQNDL  360
PVHLGGANAG NSSKPAWNSN QTIEGKADYP TMKQVLLDGV LEGGLKKLDS FDRWMSRELG  420
DVNDSHIQSS STNYWESVGN EDDNSNITPP EQIDSYMMGP SLSQDQLFSI IDFAPNWAFS  480
GSEVKVXXXX XXXRAXEEAE KCNWACMFGE LEVPAEVIAN GVLRCSTPLH EPGRVPFYVT  540
CSNRCACSEV REFEFRISSV QNEDVAVMSS VSSEESHLLI RFTKLLTAGS LSNPTNVPGA  600
AGGLSHLTNK VDSSVLDDEN EWACIQNLIS EDKFSVKKVK DQLLQKLLRD KLHLWLIQKV  660
AEDGKGPLIL DEGGQGVLHF AAALGYDWAI PPTIAGGVSV NFRDVNGWTA LHWAASYGRE  720
RTVASLISLD ANPGALTDPT PKYPSGRTPA DLAYSNGHKG IAGYLAESAL SSHLSTIELK  780
DKKDGQDVEN SELKAVQTIT ERTATPSDYG DLPHGLSMKD SLAALRNATQ AAARIHQVFR  840
VQSFQRKQIK EYGDGGSGIS DERALSLLAM RSNRAGHPAE PVHAAAIRIQ NKFRGWKGRK  900
EFLLIRQRII KIQAHVRGHQ VRKNYKKIIW SVGILDKVIL RWRRKGSGLR GFKSEAITEG  960
SGGVERSSKE DDYDFLKEGR KQTEDRLQKA LARVKSMVQY PEARDQYRRL LNVVSEMQET  1020
KTKYDRLLNN SDETAADFDD DLIDIDALLE DDTSMAASSS T

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027078238.1	0.0	calmodulin-binding transcription activator 3-like
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A068TZG3	0.0	A0A068TZG3_COFCA; Uncharacterized protein
STRING	XP_009613615.1	0.0	(Nicotiana tomentosiformis)

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]