PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_13167_iso_5

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

CAMTA

Protein Properties

Length: 1097aa MW: 121839 Da PI: 6.1207

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_13167_iso_5	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	117.1	8.7e-37	2	73	47	118
CG-1 47 vryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcywlLeeelekivlvhylevk 118 +ryfrkDG++w+kk+dgktv+E+he+LK g+v+vl+cyYah+een++fqrr+yw+Leee+++ivlvhy+evk cra_locus_13167_iso_5_len_3584_ver_3 2 LRYFRKDGHNWRKKRDGKTVKEAHERLKAGSVDVLHCYYAHGEENENFQRRSYWMLEEERSHIVLVHYREVK 73 79*******************************************************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01076	7.0E-29	1	73	IPR005559	CG-1 DNA-binding domain
PROSITE profile	PS51437	55.349	1	78	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	4.6E-30	2	71	IPR005559	CG-1 DNA-binding domain
SuperFamily	SSF81296	3.5E-11	506	592	IPR014756	Immunoglobulin E-set
SuperFamily	SSF48403	1.48E-16	686	803	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	1.4E-16	689	804	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	5.81E-13	689	801	No hit	No description
PROSITE profile	PS50297	16.626	709	813	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	1.5E-7	714	804	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	9.458	742	774	IPR002110	Ankyrin repeat
SMART	SM00248	0.0018	742	771	IPR002110	Ankyrin repeat
SMART	SM00248	250	781	810	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	1.67E-8	913	968	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	0.11	917	939	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0021	919	938	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.261	919	947	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	7.5E-4	940	962	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.578	941	965	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	8.4E-5	943	962	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1097 aa Download sequence Send to blast
XLRYFRKDGH NWRKKRDGKT VKEAHERLKA GSVDVLHCYY AHGEENENFQ RRSYWMLEEE 60 RSHIVLVHYR EVKGNRTNLI RSREATEPIP DAQETEDDIR NSEAGSCSTS KFHPYDYQVA 120 SQVTDTASLN SAQASEYGDA ESAYNHQSSS SFHTYRDLQP PVMQKAEDRH SLPVPNTYQV 180 QFPGPPNMGF DPNATSTGAP YMPEGQHDFS TWRNVIESGG LAGQPINFQT SQVTNSSMMH 240 GLLQQVLTDS LGTEPVSGSR TDGXGTVAGS ISLLHFQYSL CGNYTQQNFH ASALLFLFIV 300 ASFPQSILWL LSTDLMSLHV PNFALHTSDY SYLICKQTSE GDPLYISKWP MDQKLHPDSA 360 NKLVASSSED NIAGLHNSLA PYNVLSANQN TPQNDLPVHL GGANAGNSSK PAWNSNQTIE 420 GKADYPTMKQ VLLDGVLEGG LKKLDSFDRW MSRELGDVND SHIQSSSTNY WESVGNEDDN 480 SNITPPEQID SYMMGPSLSQ DQLFSIIDFA PNWAFSGSEV KVXXXXXXXR AXEEAEKCNW 540 ACMFGELEVP AEVIANGVLR CSTPLHEPGR VPFYVTCSNR CACSEVREFE FRISSVQNED 600 VAVMSSVSSE ESHLLIRFTK LLTAGSLSNP TNVPGAAGGL SHLTNKVDSS VLDDENEWAC 660 IQNLISEDKF SVKKVKDQLL QKLLRDKLHL WLIQKVAEDG KGPLILDEGG QGVLHFAAAL 720 GYDWAIPPTI AGGVSVNFRD VNGWTALHWA ASYGRERTVA SLISLDANPG ALTDPTPKYP 780 SGRTPADLAY SNGHKGIAGY LAESALSSHL STIELKDKKD GQDVENSELK AVQTITERTA 840 TPSDYGDLPH GLSMKDSLAA LRNATQAAAR IHQVFRVQSF QRKQIKEYGD GGSGISDERA 900 LSLLAMRSNR AGHPAEPVHA AAIRIQNKFR GWKGRKEFLL IRQRIIKIQA HVRGHQVRKN 960 YKKIIWSVGI LDKVILRWRR KGSGLRGFKS EAITEGSGGV ERSSKEDDYD FLKEGRKQTE 1020 DRLQKALARV KSMVQYPEAR DQYRRLLNVV SEMQETKTKY DRLLNNSDET AADFDDDLID 1080 IDALLEDDTS MAASSST

Sequence ? help Back to Top

Protein Sequence Length: 1097 aa Download sequence Send to blast

XLRYFRKDGH NWRKKRDGKT VKEAHERLKA GSVDVLHCYY AHGEENENFQ RRSYWMLEEE  60
RSHIVLVHYR EVKGNRTNLI RSREATEPIP DAQETEDDIR NSEAGSCSTS KFHPYDYQVA  120
SQVTDTASLN SAQASEYGDA ESAYNHQSSS SFHTYRDLQP PVMQKAEDRH SLPVPNTYQV  180
QFPGPPNMGF DPNATSTGAP YMPEGQHDFS TWRNVIESGG LAGQPINFQT SQVTNSSMMH  240
GLLQQVLTDS LGTEPVSGSR TDGXGTVAGS ISLLHFQYSL CGNYTQQNFH ASALLFLFIV  300
ASFPQSILWL LSTDLMSLHV PNFALHTSDY SYLICKQTSE GDPLYISKWP MDQKLHPDSA  360
NKLVASSSED NIAGLHNSLA PYNVLSANQN TPQNDLPVHL GGANAGNSSK PAWNSNQTIE  420
GKADYPTMKQ VLLDGVLEGG LKKLDSFDRW MSRELGDVND SHIQSSSTNY WESVGNEDDN  480
SNITPPEQID SYMMGPSLSQ DQLFSIIDFA PNWAFSGSEV KVXXXXXXXR AXEEAEKCNW  540
ACMFGELEVP AEVIANGVLR CSTPLHEPGR VPFYVTCSNR CACSEVREFE FRISSVQNED  600
VAVMSSVSSE ESHLLIRFTK LLTAGSLSNP TNVPGAAGGL SHLTNKVDSS VLDDENEWAC  660
IQNLISEDKF SVKKVKDQLL QKLLRDKLHL WLIQKVAEDG KGPLILDEGG QGVLHFAAAL  720
GYDWAIPPTI AGGVSVNFRD VNGWTALHWA ASYGRERTVA SLISLDANPG ALTDPTPKYP  780
SGRTPADLAY SNGHKGIAGY LAESALSSHL STIELKDKKD GQDVENSELK AVQTITERTA  840
TPSDYGDLPH GLSMKDSLAA LRNATQAAAR IHQVFRVQSF QRKQIKEYGD GGSGISDERA  900
LSLLAMRSNR AGHPAEPVHA AAIRIQNKFR GWKGRKEFLL IRQRIIKIQA HVRGHQVRKN  960
YKKIIWSVGI LDKVILRWRR KGSGLRGFKS EAITEGSGGV ERSSKEDDYD FLKEGRKQTE  1020
DRLQKALARV KSMVQYPEAR DQYRRLLNVV SEMQETKTKY DRLLNNSDET AADFDDDLID  1080
IDALLEDDTS MAASSST

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028076108.1	0.0	calmodulin-binding transcription activator 3-like, partial
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2R6RDE6	0.0	A0A2R6RDE6_ACTCH; Calmodulin-binding transcription activator 3 like
STRING	VIT_07s0141g00250.t01	0.0	(Vitis vinifera)

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]