PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_18915_iso_1

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

WRKY

Protein Properties

Length: 466aa MW: 50346.8 Da PI: 7.7585

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_18915_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.6	1.7e-30	122	181	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed +++++tYeg+Hnh+ cra_locus_18915_iso_1_len_1612_ver_3 122 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApNCPVRKQVQRCAEDMSILITTYEGTHNHT 181 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	8.3E-32	108	183	IPR003657	WRKY domain
SuperFamily	SSF118290	1.7E-27	114	183	IPR003657	WRKY domain
PROSITE profile	PS50811	28.001	117	183	IPR003657	WRKY domain
SMART	SM00774	1.5E-36	122	182	IPR003657	WRKY domain
Pfam	PF03106	6.7E-27	123	180	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 466 aa Download sequence Send to blast
XNNNNNSTSH DHIVKKDDQS ATNKSSSKEK DHEEDDNAGA NLALGLDCKF DLANNNNNQS 60 PNPSPETSLE EVKEDAGETW PPQKGLNKRS SNGGGDDEVL SQQNPAKRAR VSVRVRCDTP 120 TMNDGCQWRK YGQKIAKGNP CPRAYYRCTV APNCPVRKQV QRCAEDMSIL ITTYEGTHNH 180 TLPISATAMA STTSAAASML ISGSSTSAST STQSSSAPNL TSANINGLNF YLSDNSKPKP 240 FYLPNSSISS PPNSFPTITL DLTTNSSNKL LGNNLMNFPP RSYSSSTNLS FNSLESNSLP 300 ISWSNGVLNY GNIHQPYNNK NNNPIINSLS FARNPNQETL YQSYLQKTNN ILNSSQQQFH 360 QQQLPQETIA AATKAITSDP NFQSALAAAL STIIGSGNNQ QQNHNLSETF PVLSSFPVAS 420 TSNATNKCAP SSTNSQPGSL MFLSPSLPFS TSNNKSTSPD NRDQIS

Sequence ? help Back to Top

Protein Sequence Length: 466 aa Download sequence Send to blast

XNNNNNSTSH DHIVKKDDQS ATNKSSSKEK DHEEDDNAGA NLALGLDCKF DLANNNNNQS  60
PNPSPETSLE EVKEDAGETW PPQKGLNKRS SNGGGDDEVL SQQNPAKRAR VSVRVRCDTP  120
TMNDGCQWRK YGQKIAKGNP CPRAYYRCTV APNCPVRKQV QRCAEDMSIL ITTYEGTHNH  180
TLPISATAMA STTSAAASML ISGSSTSAST STQSSSAPNL TSANINGLNF YLSDNSKPKP  240
FYLPNSSISS PPNSFPTITL DLTTNSSNKL LGNNLMNFPP RSYSSSTNLS FNSLESNSLP  300
ISWSNGVLNY GNIHQPYNNK NNNPIINSLS FARNPNQETL YQSYLQKTNN ILNSSQQQFH  360
QQQLPQETIA AATKAITSDP NFQSALAAAL STIIGSGNNQ QQNHNLSETF PVLSSFPVAS  420
TSNATNKCAP SSTNSQPGSL MFLSPSLPFS TSNNKSTSPD NRDQIS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	6e-21	109	183	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027168798.1	1e-167	probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	1e-115	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A068VJ04	1e-164	A0A068VJ04_COFCA; Uncharacterized protein
STRING	XP_010256554.1	1e-127	(Nelumbo nucifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]